Dr. Minion's research focuses on molecular mechanisms of microbial pathogenesis, pathogenomics, proteomics, gene expression profiling and molecular vaccines. Current projects include the role of biofilms of E. coli O157:H7 in persistence in ruminants; gene expression profiling of Listeria monocytogenes, E. coli 0157:H7, and Mycoplasma hyopneumoniae; and the development of novel vaccines against Yersinia pestis.

MICRO 552 Bacterial Molecular Genetics and Physiology. (1-0) Cr. 1. F. Prereq: 302, Biol 313. Review of the molecular genetics and physiology of model organisms.

V MPM 625. Mechanisms of Bacterial Pathogenesis. (4-0) Cr. 4. Alt. S., offered 2009. Prereq: Credit in Biochemistry and Microbiology. Review of current concepts in specific areas of microbial pathogenesis including the genetic basis for bacterial disease, genetic regulation and control of virulence factors and their mechanisms of action, and host-pathogen interactions at the cellular and molecular levels. The application of microbial genetics to understanding pathogenesis.

University of Alabama in Birmingham - Ph.D. in Molecular and Cellular Biology, 1983, Department of Microbiology

University of Memphis - M.S. in Cell Biology, 1977

University of Memphis - B.S. in Chemistry, 1972

Minion, F. C., E. L. Lefkowitz, M. L. Madsen, B J. Cleary, S. M. Swartzell, and G. G. Mahairas. 2004. The genome sequence of Mycoplasma hyopneumoniae strain 232, the agent of swine mycoplasmosis. J. Bacteriol. 186:7123-7133.

Stakenborg, T., Vicca, J., Butaye, P., Maes, D., Minion, C., Peeters, J., de Kruif, A, Haesebrouck, F. 2005. Characterization of in vivo acquired resistance of Mycoplasma hyopneumoniae to macrolides and lincosamides. Microbial Drug Resistance 3:290-294.

Adams, C., J. Pitzer, and F. C. Minion. 2005. In vivo expression analysis of the P97 and P102 paralog families of Mycoplasma hyopneumoniae. Infect. Immun. 73:7784-7787.

Madsen, M. L., D. Nettleton, E. L. Thacker, R. Edwards, and F. C. Minion. 2006. Transcriptional profiling of Mycoplasma hyopneumoniae during heat shock using microarrays. Infect. Immun. 74: 160-166.

Jenkins, C., J. L. Wilton, F. C. Minion, L. Falconer, M. J. Walker, and S. P. Djordjevic. 2006. Two domains within the Mycoplasma hyopneumoniae cilium adhesin bind heparin. Infect. Immun. 74:481-487.

Burnett, T.A., K. Dinkla, M. Rohde, G.S. Chhatwal, M. Srivastava, S.J. Cordwell, S. Geary, F. C. Minion, M. J. Walker, S. P. Djordjevic. 2006. P159 is a proteolytically processed, surface adhesin of Mycoplasma hyopneumoniae: defined domains of P159 bind heparin and promote adherence to eukaryotic cells. Mol. Microbiol. 60:669-686.

Madsen, M. L., D. Nettleton, E. L. Thacker, and F. C. Minion. 2006. Transcriptional profiling of Mycoplasma hyopneumoniae during iron depletion using microarrays. Microbiology 152:937-944.

Schafer, E. R., M. J. Oneal, M. L. Madsen, F. C. Minion. 2007. Global transcriptional analysis of Mycoplasma hyopneumoniae following exposure to hydrogen peroxide. Microbiol. 153:3785-3790.

Madsen, M. L., M. J. Oneal, S. W. Gardner, E. L. Strait, D. Nettleton, E. L. Thacker, and F. C. Minion. 2007. Array-based genomic comparative hybridization of field strains of Mycoplasma hyopneumoniae. J. Bacteriol. 189:7977-7982.

Vicca, J., D. Maes, T. Stakenborg, P. Butaya, F. Minion, J. Peeters, A. De Kruif, A. Decostere, and F. Haesebrouck. 2007. Resistance mechanism against fluoroquinolones in Mycoplasma hyopneumoniae field isolates. Microb. Drug Resist. 13:166-170.

Madsen, M. L., S. Puttamreddy, E. L. Thacker, M. D. Carruthers, F. C. Minion. 2008. Transcriptome changes in Mycoplasma hyopneumoniae during infection. Infect. Immun. 76:658-663.

Chang, L.-J., W.-H. Chen, F. C. Minion and D. Shiuan. 2008. Mycoplasmas regulate the expression of heat shock protein genes through CIRCE-HrcA interactions. Biochem. Biophys. Res. Commun. 367:213-218.

Puttamreddy, S., M. D. Carruthers, M;. L. Madsen, and F. C. Minion. 2008. Transcriptome analysis of organisms with food safety relevance. Foodborne Pathog. Dis. 5:517-529.

Strait, E. L., M. L. Madsen, F. C. Minion, J. Christopher-Hennings, M. Dammen, K. R. Jones, E. L. Thacker. 2008. Real-time PCR assays to address genetic diversity in Mycoplasma hyopneumoniae. J. Clin. Microbiol. 46:2491-2498.

Oneal, M. J., E. R. Schafer, M. L. Madsen and F. C. Minion. 2008. Global Transcriptional Analysis of Mycoplasma hyopneumoniae Following Exposure to Norepinephrine. Microbiol. 154:2581-2588.

Wilton, J., C. Jenkins, S. Cordell, L. Falconer, F. Minion, D. Oneal, M. Djordjevic, A. Connolly, I. Barchia, M. Walker, and S. P. Djordjevic. 2009. Mhp493 (P216) is a proteolytically processed, cilium and heparin binding protein of Mycoplasma hyopneumoniae. Mol. Micro. 71: 566-582.

Information Officer, International Organization for Mycoplasmology, 2002-present. Chair, University Biohazards and Public Health Committee, 1999-2006. Editorial Board for Infection and Immunity (2001-2009) Editorial Board for Foodborne Pathogens and Disease (2004-present) President, Iowa State University Graduate Council, 2001-2003. Information Officer, International Organization for Mycoplasmology, 2002-present. Chair, International Research Programme for Comparative Mycoplasmology, 1996-2000. Councilor at Large, American Society for Microbiology, 1998-2000. Chair, Division G, American Society for Microbiology, 1996-1997.

NIH Research Career Development Award, 1991-1996 Louis Dienes Award in Mycoplasmology, 1992 SmithKline Beecham Award for Research Excellence, 1993

American Society for Microbiology

International Organization for Mycoplasmology

American Association for the Advancement of Science

Phi Zeta

Sigma Xi