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Probiotic Effects in Canine IBD

CLINICAL TRIAL:

Probiotic Effects in Canine IBD

BY Johnna Decker

 

Dr. Al Jergens, professor of internal medicine, is conducting a clinical research trial evaluating the effects of human probiotic VSL#3 in dogs with IBD (Inflammatory Bowel Disease). This study will assess the utility of probiotics as an adjunct to standard treatment using diet and drugs. 

The trial is an eight-week monitoring period with clinic-pathologic evaluations performed on the third and eighth week. Dogs are randomized to receive standard therapy with or without probiotic VSL#3.

For study enrollment, dogs must be diagnosed with IBD which includes mucosal biopsy with histopathologic evidence of intestinal inflammation. Pilot observations indicate that the probiotic is palatable and well tolerated, that it reduces histologic inflammation and clinical disease activity, and that it promotes alterations in mucosal-associated bacteria.

Dogs with chronic enteropathy might serve as potential study candidates.

 

 

 

  Albert Jergens DVM, MS, PhD, DACVIM (Small Animal) Professor and Associate Chair of Research and Graduate Studies

>> For more information
please email Dr. Jergens
or call 515 294-4900.