Dr. Thoen conducts investigations on the pathogenesis of Mycobacterium bovis, M. tuberculosis, M. avium ss paratuberculosis, M. avium ss avium and M. avium ss intracellulare in domestic and captive wild animals. The focus of research is to provide an improved understanding of host immune responses that can be used in developing more reliable diagnostic tests.

Infectious Diseases of Captive Wild Animals -- VMPM 409 - Instructor
Zoo Medicine Preceptorship -- VMPM 494 - Instructor in Charge
Zoonosis -- VMPM 536 (Graduate Course) - Instructor in Charge
Wild Animal Health and Conservation -- VMPM 496 -- Instructor in Charge
Pathogenic Bacteriology - VMPM 586 - Lecturer
 

D.V.M.: University of Minnesota, 1961.
Ph.D.: University of Minnesota, Mayo Graduate School of Medicine, 1971.
Honorary Diplomate: American Veterinary Epidemiology Society, 2005

Thoen, C. O., LoBue, P. A., Enarson, D. L., Kaneene, J. and de Kantor, I. 2009.  (Invited). Tuberculosis: a reemerging disease in animals and humans.  Vet. Italiania 45(1): 135-181

Thoen, C.O. 2010.  Tuberculosis In: Merck Veterinary Manual, Tenth Edition. Ed. Cynthia Kahn & S. Line, Merck and Co. Inc. Whitehouse Station N.J. (In Press)

Thoen, C.O., Williams, D. E. and Thoen, T. C. . 2008 (Invited). Discovery of Streptomycin for the Treatment of Tuberculosis. One Health Newsletter. 1(3): 5-6

Olsen, I. Barletta, R. & Thoen, C. O., 2010.  Mycobacterium. In: Pathogenesis of Bacterial Infections in Animals.  Blackwell- Willey, Inc.  (In Press).

Wilkins, M.J. Bartlett, P. C., Berry, D. E., Perry, R. L. Fitzgerald, S. D., Bernardo, T. M., Thoen, C. O. and Kaneene, J. B. 2008. Absence of Mycobacterium bovis infection in dogs and cats residing on infected cattle farms: Michigan, 2002. Epidemiol. Infect. 1:1-7.

Thoen, C. O. and LoBue, P. A. 2007 (Invited). Mycobacterium bovis tuberculosis: Forgotten, but Not Gone. Lancet 369(9569):1236-1238

Thoen, C. O., 2007. Johne's Disease. In: McGraw-Hill Encyclopedia of Science and Technology ed. L. Geller. Tenth Edition. McGraw-Hill Professional New York 9:515-516

Thoen, C.O. and Barletta, R. 2006. Pathogenesis of Mycobacterium bovis. In. Mycobacterium bovis Infection in Animals and Humans. Eds. C. O.Thoen, J. H. Steele and M. J. Gilsdorf. Chapter 4. pp 18-33. Blackwell Publishing, Ames, IA

Platt, R., Roth, J. A., Royer, R. L. and Thoen, C. O. 2006. Monitoring
responses by use of five-color flow cytometry in subsets of peripheral T
cells obtained from cattle inoculated with a killed Mycobacterium avium
subsp paratuberculosis vaccine. Amer. Jour. Vet. Res. 67(12): 2050 - 2058

Thoen, C.O., LoBue, P. A. and de Kantor, I. 2006. The importance of
Mycobacterium bovis as a Zoonosis. Vet. Microbiol. 112: 339 – 345.

Thoen, C. O., Robbe-Austerman, S., Whitlock, R. H., Hoards Rubl. 2006. Don't overlook vaccination for control of Johne's. p. 666, Hoard's Dairyman Journal

Thoen, C.O., Steele, J. H. and Gilsdorf, M. J. 2006. Mycobacterium bovis
infection in Animals and Humans. Second Edition, pp. 329, Blackwell
Publishing, Ames, IA.

Helgerson, J. L., Weston, K. D., Jarnagin, J. L. and Thoen, C.O., 2006.
Natural exposure of purchased heifers in Johne's positive herd. In:
Proceedings of the 39th Annual Conference of American Assoc. Bovine
Practitioners, Saint Paul, MN

Thoen, C.O. 2006. Tuberculosis. In: Diseases of Swine. Eds. B. E.Straw, J. J. Zimmerman, S. D'Allaire and D. J. Taylor. Ninth edition. Chapter 49. pp. 807– 816. Blackwell, Publishing, Ames, IA

Robbe-Austerman, S., Gardner, I. A, Thomsen, B. V., Morrical, D. G., Martin, B. M., Palmer, M. V., Thoen, C. O. and Ewing, C. E. 2006. Sensitivity and specificity of the agar-gel-immunodiffusion test, ELISA and the skin test for detection of paratuberculosis in United States Midwest sheep populations. Vet. Res. 37: 553- 564.

Thoen, C.O. and Ebel, E. D. 2006. Diagnostic Tests for Bovine Tuberculosis. In: Mycobacterium bovis Infection in Animals and Humans, Chapter 6. pp. 49-53, Blackwell, Publishing, Ames, IA

Thoen, C.O. 2005. Tuberculosis. The Merck Veterinary Manual. Ed. Cynthia Kahn. pp. 549 - 555. Merck and Co. Inc. Whitehouse Station, NJ.

Thoen, C.O. and Barletta, R. 2004. Mycobacterium. In: Pathogenesis of
Bacterial Infections in Animals. Editors: C. L. Gyles, J. F. Prescott, J. G.
Songer, C. O. Thoen. Third Edition. Chapter 6. pp 69 – 76. Blackwell
Publishing, Ames, IA.

Kaneene, J.and Thoen, C.O. 2004. Tuberculosis. Invited. Zoonosis Updates. Jour. Amer. Vet. Med.Assoc. 224:695 -691.

Olsen, S. C., Thoen, C. O. and Cheville, N. F. 2004. Brucella. In: Pathogenesis of Bacterial Infections in Animals. Eds. C. L. Gyles, J. F. Prescott, J. G. Songer and C. O. Thoen. Chapter 22. pp. 309-319.

Fulton, R. M. and Thoen, C. O. 2003. Tuberculosis. In: Diseases of Poultry. pp. 836-844. Iowa State Press. Ames, IA.

Steadham, E.M., Martin, B.M., and Thoen, C.O. 2002. Production of a Mycobacterium avium ssp. paratuberculosis purified protein derivative (PPD) and evaluation of potency in guinea pigs. Biologicals. 30:93-95.

Kaneene, J.B., Bruning-Fann, C.S., Dunn, J., Mullaney, T.P., Berry, D., Massey, J.P., Thoen, C.O., Halstead, S., and Schwartz, K. 2002. Epidemiologic investigation of Mycobacterium bovis in a population of cats. Am.Jour.Vet.Res. 11: 1507-1511.

Thoen, C.O. and Garcia-Marin, J.F. 2002. Mycobacterium. Invited. Animal Health and Production Compendium. CAB International..

Mikota, S.K., Peddie, L., Peddie, J., Issasa, R., Thoen, C.O., et al. 2001. Epidemiology and Diagnosis of Mycobacterium tuberculosis in elephants. Journal of Zoo Wildlife Medicine. 32(1): 1 -16.

Just, S.D., Thoen, C.O., Thacker, B.J., Thomson, J.U. 2001. Monitoring of Lawsonia intracellularis by indirect serum immunofluorescence assay in a commercial swine production system. Journal of Swine Health Production. 9(2):57-61.

Gilsdorf, M.J., Thoen, C.O., Temple, R.M.S. et al. 2001. Experimental exposure of llamas (Lama glama) to Brucella abortus: Humoral antibody response. Vet. Microbiol. 81:85-91.

Capsel, R.L., Olsen, S.C., Cheville, N.F., Thoen, C.O. 2000. Survival of Brucella abortus Strain RB51 lyophilized and as liquid vaccine under different storage conditions. Biologicals 28:209-215.

Hornsby, R.L., Jensen, A.E., Olsen, S.B., Thoen, C.O. 2000. Selective Media for Isolation of Brucella abortus strain RB51. Vet. Microbiol. 43:51-60.

Brees, D.J., Reimer, S.B., Cheville, N.F., Florence, A. and Thoen, C.O. 2000. Immunochemical Detection of Mycobacterium paratuberculosis in formalin-fixed, paraffin-embedded bovine tissue sections. Jour. Vet Diagn. Invest. 12:60-63.

Associate Editor, The International Journal of Tuberculosis and Lung Disease: 2002 to present.

Editor, Mycobacterium bovis Infection in Animals and Humans.  2006. Second Edition,  Blackwell Publishing.

Associate Editor, Pathogenesis of Bacterial Infections.  2010.  Fourth Edition.  Blackwell Publishing, Ames

Chair, Department of Veterinary Microbiology, College of Veterinary Medicine, ISU.  1998 -2001.

Chair, Admissions Committee, College of Veterinary Medicine, 2000 to 2007

Investigator, Johne’s Disease Integrated Program, U.S. Department of Agriculture, 2004 to present

Chair, Scientific Committee on Tuberculosis in Animals, International Union Against Tuberculosis and Lung Disease. 1997-2005.

United States Animal Health Association. Member of the following committees:
a.) Paratuberculosis, b.) Tuberculosis, c.) Infectious Diseases of bison, llama and cattle, d.) Wildlife Disease, and e.) Alternate Species

American Association of Veterinary Laboratory Diagnosticians
National Tuberculosis Advisory Committee for Zoo Animals
National Johne's Working Group - member
National Elephant Tuberculosis Advisory Panel - member
National Johne's Integrated Program - member

Karl F. Meyer - James H. Steele Gold Cane Award, (2009) - American Epidemiology Society - American Veterinary Medical Association.

Iowa Board of Regents Award for Faculty Excellence  1999.

Honary Diplomate, American Veterinary Epidemiology Society.  2005.

Outstanding Academic Advisor, 1996.

American Veterinary Medical Association
International Union Against Tuberculosis and Lung Disease
American Society for Microbiology
Conference Research Workers in Animal Disease
American Association of Veterinary Laboratory Diagnosticians
United States Animal Health Association
Iowa Veterinary Medical Association