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Prevalence of Anti-PCV2-Antibodies

The mean PCV2-antibody half-life in weanling pigs is estimated to be 19.0 days and the window for PCV2-passive antibody decay within a population is relatively wide (Opriessnig et al., 2004). Serological studies have demonstrated that passively-acquired PCV2 antibodies decay during lactation and early postweaning periods to negative or near negative levels at the end of the nursery period (7 weeks of age) followed by active seroconversion of the majority of the population starting around 12 weeks of age (Roríguez-Arrioja et al., 2002). Allan et al. (1994) showed a similar trend for PCV1 passive antibody decay. Larochelle et al. (2003) did a comparative serologic and virologic study in 5 PMWS-affected herds and 2 herds without PMWS in Quebec. Sixty blood samples were collected in each herd in 4-week-intervals from 3-to 23-week-old pigs and it was found that all herds had similar PCV2 profiles: low PCV2-antibody levels were present at 3 weeks of age and reached very low-to-negative levels by 11 weeks of age. PCV2-infection as determined by PCR took place from 11 to 15 weeks of age at which time PCV2 seroconversion occurred. All pigs were seropositive at 23 week of age.

PCV2-passively-acquired antibodies present at 1-2 weeks of age were found to decay below ELISA cutoff level by approximately 4.9 ± 1.2 weeks of age in piglets with low levels of antibodies at weaning, by approximately 8.1 ± 1.9 weeks of age in piglets with moderate levels of antibodies at weaning, and by approximately 11.1 ± 2.5 weeks of age in piglets with high levels of antibodies at weaning (Opriessnig et al., 2004).

Serological surveys found that PCV-antibodies are present globally in almost all swine herds tested and in up to 100% of individual pigs within herds. There is a high prevalence of PCV infection in the global swine populations of Canada, France, Germany, New Zealand, Northern Ireland, United Kingdom, and the United States (Allan et al., 1994; Dulac and Afshar,1989; Edwards and Sands, 1994; Hines and Lukert, 1995; Horner, 1991; Magar et al., 2000; Tischer et al., 1982, 1986, 1995a; 1995b; Walker et al., 2000). Magar et al. (2000) found that PCV2 appeared to be the main PCV2 type circulating in Canadian pig herds and that serological evaluation using PCV1 underestimated the seroprevalence of PCV2. Most U.S. breeding herds and the majority of the sows within those herds were found to be seropositive for PCV2 (Opriessnig et al., 2004). Sibila et al. (2004) determined the presence of PCV2-antibodies by ELISA in 5 farms without a history of PMWS and in 4 farms with PMWS. Serum antibodies were detected in a higher percentage of pigs from PMWS farms but overall a high prevalence of PCV2 infection was found (Sibila et al., 2004)


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Walker IW, Konoby CA, Jewhurst VA, McNair I, McNeilly F, Meehan BM, Cottrell TS, Ellis JA, Allan GM: Development and application of a competitive enzyme-linked immunosorbent assay for the detection of serum antibodies to porcine circovirus type 2. J Vet Diagn Invest. 12:400-405, 2000




Derivation of PCV2-free pigs

Examples of typical Herd Profiles

General Info






Molecular Organization


Host Range


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