header shadow

Age

PMWS is observed most often in pigs between 5 and 18 weeks of age with most cases occurring between 6 and 10 weeks of age. Reports of PMWS in adult pigs are rare. PCV2-associated lesions are typically observed from 14 to 35 days post PCV2 inoculation in experimental studies. This suggests that pigs in the field are most likely infected between 1 and 10 weeks of age. Studies investigating the influence of age on PCV2-infection are lacking. In experimental models described to date in the literature, pigs that were singularly-infected with PCV2 (no coinfection or immune stimulation) and developed clinical PMWS were between 1-21 days of age when inoculated. PMWS in older pigs was observed only in purebred Landrace pigs (35-39 days of age) (Opriessnig et al., 2006) or with additional coinfections or immune stimulation (i.e. vaccination).

References:
Opriessnig T, Fenaux M, Thomas P, Hoogland MJ, Rothschild M, Meng XJ, Halbur PG: Evidence of breed-dependent differences in susceptibility to porcine circovirus type 2-associated disease and lesions. Vet Pathol. In press, 2006a

FACTORS

Coinfections

Immunostimulation

Immunosuppression

Gender

Host Susceptibility

Antibody Levels

PCV2 Isolates

PCV2

General Info

Research

Control

Diagnosis

Factors

PCVAD

Molecular Organization

Pathogenesis

Host Range

Epidemiology

Related Links