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Dr. Tanja Opriessnig - Publications

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Porcine circovirus type 2 (PCV2)

Opriessnig T, Prickett JR, Madson DM, Shen HG, Juhan NM, Pogranichniy RM, Meng XJ, Halbur PG: Porcine circovirus type 2 (PCV2)-infection and re-inoculation with homologous or heterologous strains: Virological, serological, pathological and clinical effects in growing pig. Veterinary Research. 41:31, 2010

Opriessnig T, Patterson AR, Madson DM, Pal N, Ramamoorthy S, Meng XJ, Halbur PG: Comparison of the efficacy of passive (dam) versus active (piglet) vaccination against porcine circovirus type 2 (PCV2) and impact of passively-derived PCV2 vaccine-induced antibodies on vaccination. Veterinary Microbiology. Available online.

Juhan NM, LeRoith T, Opriessnig T, Meng XJ: The open reading frame 3 (ORF3) of porcine circovirus type 2 (PCV2) is dispensable for virus infection but evidence of reduced pathogenicity is limited in pigs infected by an ORF3-null PCV2 mutant. Virus Research. 147:60-66, 2010.

Gillespie J, Opriessnig T, Meng XJ, Pelzer K, Buechner-Maxwell V: Porcine circovirus type 2 and porcine circovirus associated disease. Journal of Veterinary Internal Medicine. 23:1151-1163, 2009.

Baker RB, Madson DM, Patterson AR, Opriessnig T: Evaluation of the safety of different porcine circovirus type 2 (PCV2) tissue homogenate vaccines in a pig bioassay. Veterinary Record. 165:262-265, 2009

Madson DM, Patterson AR, Ramamoorthy S, Pal N, Meng XJ, Opriessnig T: Effect of natural or vaccine induced porcine circovirus type 2 (PCV2) immunity on fetal infection after artificial insemination with PCV2 spiked semen. Theriogenology. 72:747-754, 2009. [View publication]

Madson DM, Patterson AR, Ramamoorthy S, Meng XJ, Opriessnig T: Effect of porcine circovirus type 2 (PCV2) vaccination of the dam on replication of PCV2 in utero. Clinical and Vaccine Immunology. 16:830-834, 2009 [View publication]

Madson DM, Patterson AR, Pal N, Ramamoorthy S, Meng XJ, Opriessnig T: Reproductive failure experimentally induced in sows via artificial insemination with semen spiked with porcine circovirus type 2 (PCV2). Veterinary Pathology. 46:707-716, 2009.

 

 

Opriessnig T, Patterson AR, Madson DM, Pal N, Rothschild M, Kuhar D, Lunney J, Juhan NM, Meng XJ, Halbur PG: Difference in severity of porcine circovirus type 2 (PCV2)-induced pathological lesions between selected Landrace and Pietrain pigs. Journal of Animal Science. 87:1582-1590, 2009.

Opriessnig T, Patterson AR, Madson DM, Pal N, Halbur PG: Comparison of efficacy of commercial one dose and two dose PCV2 vaccines using a mixed PRRSV-PCV2-SIV clinical infection model 2-3 month post vaccination. Vaccine. 27:1002–1007, 2009. [View publication] 

Opriessnig T, Patterson AR, Meng XJ, Halbur PG: Porcine circovirus type 2 in muscle and bone marrow is infectious and transmissible to naïve pigs by oral consumption. Veterinary Microbiology. 133:54-64, 2009. [View publication]

Patterson AR, Johnson J, Ramamoorthy S, Meng XJ, Halbur PG, Opriessnig T: Comparison of the ability of three ELISAs to detect porcine circovirus-2 (PCV2)-specific antibodies after vaccination or inoculation with genetically distinct PCV1 or PCV2 isolates. Journal of Veterinary Diagnostic Investigation. 20: 744-751, 2008. [View publication

Madson DM, Ramamoorthy S, Kuster C, Pal N, Meng XJ, Halbur PG, Opriessnig T: Characterization of shedding patterns of porcine circovirus type 2a and PCV2b in inoculated mature boars. Journal of Veterinary Diagnostic Investigation. 20:725-734, 2008. [View publication]

Opriessnig T, Ramamoorthy S, Madson DM, Patterson AR, Pal N, Carman S, Meng XJ, Halbur PG. Porcine circovirus type 2a and 2b isolates are similar in virulence and prior infection with either 2a or 2b isolate provides heterologous protection. Journal of General Virology. 89:2482-2491, 2008. [View publication]

Opriessnig T, Madson DM, Prickett JR, Kuhar D, Lunney JK, Elsener J, Halbur PG. Effect of porcine circovirus type 2 (PCV2) vaccination on porcine reproductive and respiratory syndrome virus (PRRSV) and PCV2 coinfection. Veterinary Microbiology. 131:103-114, 2008. [View publication]

Opriessnig T, Patterson AR, Elsener, J, Meng XJ, Halbur PG: Influence of porcine circovirus type 2 (PCV2) maternal antibodies on efficacy of PCV2 vaccination to protect pigs from experimental infection with PCV2. Clinical and Vaccine Immunology. 15:397-401, 2008.  [View publication]

Rapp-Gabrielson VJ, Hoover T, Sornsen S, Kesl L, Taylor L, Jolie R, Runnels P, Weigel D, Yu S, Opriessnig T, Ruebling-Jass K, Strait E, Halbur PG: Effect of Mycoplasma hyopneumoniae vaccination in pigs co-infected with M. hyopneumoniae and porcine circovirus type 2. Journal of Swine Health and Production. 16:16-26, 2008.  [View publication]

Pal N, Huang WY, Madson DM, Kuster C, Meng XJ, Halbur PG, Opriessnig T: Development of a duplex real-time PCR for the simultaneous detection and quantification of porcine circovirus type 2 and an internal control on porcine semen samples. Journal of Virological Methods. 149:217-225, 2008. [View publication]

Opriessnig T, Meng XJ, Halbur PG. Porcine circovirus type 2 associated disease (PCVAD): Update on current terminology, clinical manifestations, pathogenesis, diagnosis, and intervention strategies. Journal of Veterinary Diagnostic Investigation, 19:591-615, 2007.  [View publication]

Thomas PJ, Opriessnig T, Juhan NE, Meng XJ, Halbur PG: Planned exposure to porcine circovirus type 2 by serum injection is not effective at preventing porcine circovirus associated disease. Journal of Swine Health and Production 15:330-338, 2007.  [View publication]

Lager KM, Gauger PC, Vincent AL, Opriessnig T, Kehrli  M, Cheung AK. Mortality in pigs given PCV2 subgroup 1 and 2 virus derived from DNA clones. Veterinary Record, 161:428-429, 2007. 

Yu S, Vincent A, Opriessnig T, Carpenter S, Kitikoon P, Halbur PG, Thacker E. Quantification of PCV2 capsid transcript in peripheral blood mononuclear cells (PBMCs) in vitro. Veterinary Microbiology 123:34-42, 2007.

Yu S, Opriessnig T, Kitikoon P, Nilubol D, Halbur PG, Thacker E. Porcine circovirus type 2 (PCV2) distribution and replication in tissues and immune cells in early infected pigs. Veterinary Immunology and Immunopathology, 115:261-272, 2007. [View publication]

McKeown NE, Opriessnig T, Thomas P, Guenette DK, Elvinger F, Fenaux M, Halbur PG, Meng X-J.  Effects of porcine circovirus (PCV2) maternal antibodies on experimental infection of piglets with PCV2. Clinical and Diagnostic Laboratory Immunology, 12:1347-1351, 2006. [View publication]

Opriessnig T, McKeown NE, Zhou EM, Meng XJ, Halbur PG. Genetic and experimental comparison of porcine circovirus type 2 (PCV2) isolates from cases with and without PCV2-associated lesions provides evidence for differences in virulence. Journal of General Virology, 87:2923-2932, 2006.  

Opriessnig T, McKeown NE, Harmon KL, Meng XJ, Halbur PG. Porcine circovirus type 2 infection decreases the efficacy of a modified live porcine reproductive and respiratory syndrome virus vaccine. Clinical and Vaccine Immunology, 13:923-929, 2006. [View publication

Opriessnig T, Fenaux M, Thomas P, Hoogland MJ, Rothschild M, Meng XJ, Halbur PG. Evidence of breed-dependent differences in susceptibility to porcine circovirus type 2-associated disease and lesions.  Veterinary Pathology, 43:281-293, 2006. [View publication

Hoogland MJ, Opriessnig T, Halbur PG. Effects of adjuvants on porcine circovirus type 2-associated lesions. Journal of Swine Health and Production, 14:133-139, 2006. [View publication

Opriessnig T, Halbur PG, Yu S, Thacker EL, Fenaux M, Meng XJ. Effects of the timing of the administration of Mycoplasma hyopneumoniae bacterin on the development of lesions associated with porcine circovirus type 2. Veterinary Record, 158:149-154, 2006.

Opriessnig T, Kuster C, Halbur PG. Demonstration of porcine circovirus type 2 in the testes and accessory sex glands of a boar. Journal of Swine Health and Production, 14:42-45, 2006.  [View publication]

Opriessnig T, Janke BH, Halbur PG. Cardiovascular lesions in pigs naturally or experimentally infected with porcine circovirus type 2. Journal of Comparative Pathology, 134:105-110, 2006.  [View publication]

Yu S, Carpenter S, Opriessnig T, Halbur PG, Thacker E. Development of a reverse transcription-PCR assay to detect porcine circovirus type 2 transcription as a measure of replication. Journal of Virological Methods 123:109-112, 2005.  [View publication]

Fenaux M, Opriessnig T, Halbur PG, Elvinger F, Meng XJ. Two amino acid mutations in the capsid protein of type 2 porcine circovirus (PCV2) enhanced PCV2 replication in vitro and attenuated the virus in vivo. Journal of Virology 78:13440-13446, 2004. [View publication

Fenaux M, Opriessnig T, Halbur PG, Xu Y, Potts B, Meng XJ. Detection and in vitro and in vivo characterization of porcine circovirus DNA from a porcine-derived commercial pepsin product. Journal of General Virology. 85:3377-82, 2004.   [View publication]

Opriessnig T, Thacker EL, Yu S, Fenaux M, Meng XL, Halbur PG. Experimental reproduction of postweaning multisystemic wasting syndrome in pigs by dual-infection with Mycoplasma hyopneumoniae and porcine circovirus type 2. Veterinary Pathology. 41:624-640, 2004. [View publication]

Opriessnig T, Yu S, Thacker E, Halbur PG. Derivation of porcine circovirus type 2-negative pigs from positive breeding herds. Journal of Swine Health and Production 12:186-191, 2004.  [View publication]

Fenaux M, Opriessnig T, Halbur PG, Elvinger F, Meng XJ. A chimeric porcine circovirus (PCV) with the immunogenic capsid gene of the pathogenic PCV type 2 (PCV2) cloned into the genomic backbone of the nonpathogenic PCV1 induced protective immunity against PCV2 infection in pigs. Journal of Virology 78:6297-6303, 2004. [View publication]

Opriessnig T, Fenaux M, Yu S, Evans RB, Cavanaugh D, Gallup JM, Pallares FJ, Thacker EL, Lager KM, Meng X-J, Halbur PG. Effect of porcine parvovirus vaccination on the development of PMWS in segregated early weaned pigs coinfected with type 2 porcine circovirus and porcine parvovirus. Veterinary Microbiology 98:209-220, 2004.  [View publication]

Fenaux M, Opriessnig T, Halbur PG, Meng X-J. Immunogenicity and pathogenicity of chimeric infectious DNA clones of pathogenic type 2 porcine circovirus (PCV2) and nonpathogenic PCV1 in weanling pigs.  Journal of Virology 77:11232-11243, 2003.  [View publication]

Opriessnig T, Yu S, Gallup JM, Evans RB, Fenaux M, Pallares F, Thacker EL, Brockus CW, Ackermann MR, Thomas P, Meng X-J, Halbur PG. Effect of vaccination with selective bacterins on conventional pigs infected with type 2 porcine circovirus. Veterinary Pathology 40:521-529, 2003.  [View publication]

Pallares FJ, Halbur PG, Opriessnig T, Sorden SD, Villar D, Janke BH, Yaeger MJ, Larson DJ, Schwartz KJ, Yoon KJ, Hoffman LJ. Porcine circovirus type 2 (PCV-2) co-infections in U. S. field cases of postweaning multisystemic wasting syndrome (PMWS). Journal of Veterinary Diagnostic Investigation 14:515-519, 2002.   [View publication]

Schmoll F, Opriessnig T, Schilcher F, Leeb B, Bauder B, Schuh M. Erstmalige Beschreibung des "Postweaning multisystemic wasting syndrome" (PMWS) in einem österreichischen Schweinebetrieb. Wiener Tierärztliche Monatsschrift 89:50-56, 2002.
 

Hepatitis E virus (HEV)

Pudupakam RS, Huang YW, Opriessnig T, Halbur PG, Pierson FW, Meng XJ: Deletions of the hypervariable region (HVR) in open reading frame 1 of hepatitis E virus do not abolish virus infectivity: evidence for attenuation of HVR deletion mutants in vivo. Journal of Virology. 83:384-395, 2009.   [View publication]

Feagins AR, Opriessnig T, Huang YW, Halbur PG, Meng XJ: Cross-species infection of specific-pathogen-free pigs by a genotype 4 strain of human hepatitis E virus. Journal of Medical Virology. 80:1379-1386, 2008.   [View publication]Feagins AR, Opriessnig T, Guenette DK, Halbur PG, Meng XJ: Inactivation of infectious hepatitis E virus present in commercial pig livers sold in local grocery stores in the United States. International Journal of Food Microbiology 23:32-37, 2008.  [View publication]

Feagins AR, Opriessnig T, Guenette DK, Halbur PG, Meng XJ. Detection and characterization of infectious Hepatitis E virus from commercial pig livers sold in local grocery stores in the USA. Journal of General Virology 88:912-917, 2007.  [View publication]

Huang YW, Opriessnig T, Halbur PG, Meng XJ. Initiation at the third in-frame AUG codon of open reading frame 3 of the Hepatitis E virus is essential for viral infectivity in vivo. Journal of Virology, 81:3018-3026, 2007.   [View publication]
 
Kasorndorkbua C, Opriessnig T, Huang FF, Guenette DK, Thomas PJ, Meng XJ, Halbur PG. Infectious swine hepatitis E virus (HEV) is present in pig manure storage facilities on U.S. farms but evidence of water contamination is lacking. Applied and Environmental Microbiology, 71:7831-7837, 2005.   [View publication]

Porcine reproductive and respiratory syndrome virus (PRRSV)

Patel D, Opriessnig T, Stein DA, Halbur PG, Meng XJ, Iversen PL, Zhang YJ: Characterization of Morpholino Oligomer Inhibition of Porcine Reproductive and Respiratory Syndrome Virus. Antiviral Research. 77:95–107, 2008. [View publication]

Opriessnig T, Baker RB, Halbur PG: Use of an experimental model to test the efficacy of planned exposure to live porcine reproductive and respiratory syndrome virus (PRRSV). Clinical and Vaccine Immunology. 14:1572-1577, 2007.    [View publication]

Grosse Beilage E, Opriessnig T, Brakmann B, Nathues H, Fiebig K, Greiser-Wilke I, Baumgärtner W. Die Infektion mit dem EU-Typ des PRRSV als Ursache zentralnervöser Störungen bei Saugferkeln [Infection with the EU genotype of PRRSV as cause of central-nervous disorders in suckling pigs – A case report]. Tierärztliche Praxis Großtiere 35:294-298, 2007.

Opriessnig T, Pallarés FJ, Nilubol D, Vincent AL, Thacker EL, Vaughn EM, Roof M, Halbur PG.  Genomic homology of ORF 5 gene sequence between modified live vaccines and porcine reproductive and respiratory syndrome virus challenge isolates is not predictive of vaccine efficacy.  Journal of Swine Health and Production, 13:246-253, 2005.  [View publication]

Opriessnig T, Halbur PG, Yoon K-J, Pogranichniy RM, Harmon KM, Evans R, Key KF, Pallares FJ, Thomas P, Meng X-J. Comparison of molecular and biological characteristics of a modified live porcine reproductive and respiratory syndrome vaccine (Ingelvac PRRS MLV), the parent strain of the vaccine (ATCC VR2332), ATCC VR2385, and two recent field isolates of PRRSV. Journal of Virology 76:11837-11844, 2002.   [View publication]

Pallares FJ, Halbur PG, Opriessnig T, Vaughn EM, Paul PS. Effects of dual infection of SPF pigs with low virulent isolates of porcine respiratory coronavirus (PRCV) and porcine reproductive and respiratory syndrome virus (PRRSV). Anaporc Científico, Spain. 2:8-13, 2002.

Erysipelothrix rhusiopathiae

Opriessnig T, Bender JS, Halbur PG: Development and validation of an immunohistochemical method for the rapid diagnosis of swine erysipelas in formalin-fixed paraffin-embedded tissue samples. Journal of Veterinary Diagnostic Investigation. 22:86-90, 2010.

Pal N, Bender SB, Opriessnig T: Rapid detection and differentiation of Erysipelothrix spp. by a novel multiplex real-time PCR assay. Journal of Applied Microbiology. 108:1083–1093, 2010.

Bender JS, Kinyon JM, Kariyawasam S, Halbur PG, Opriessnig T: Comparison of conventional direct and enrichment culture methods for Erysipelothrix spp. from experimentally and naturally infected swine.  Journal of Veterinary Diagnostic Investigation. 21:863-868, 2009.

Opriessnig T, Hoffman LJ, Harris DL, Gaul SB, Halbur PG. Erysipelothrix rhusiopathiae: genetic characterization of midwest US isolates and live commercial vaccines using pulsed-field gel electrophoresis. Journal of Veterinary Diagnostic Investigation 16:101-107, 2004. [View publication]

Opriessnig T, Vance RK, Halbur PG. Erysipelothrix rhusiopathiae septicemia in a Laughing Kookaburra (Dacelo novaeguineae). Journal of Veterinary Diagnostic Investigation, 17:497-499, 2005.  [View publication]

Streptococcus suis

Pallares FJ, Halbur PG, Schmitt CS, Roth JA, Opriessnig T, Thomas PJ, Kinyon JM, Murphy D, Frank DE, Hoffman LJ. Comparison of experimental models for Streptococcus suis infection of conventional pigs. Canadian Journal of Veterinary Research 67:225-228, 2003.  [View publication]

Porcine respiratory coronavirus (PRCV)

Halbur PG, Pallares FJ, Opriessnig T, Vaughn EM, Paul PS. Pathogenicity of three isolates of porcine  respiratory coronavirus in the USA. Veterinary Record 152:358-361, 2003.  [View publication]

Case reports

Madson DM, Loynachan AT, Kariyawasam S, Opriessnig T: Systemic Conidiobolus incongruus infection and hypertrophic osteopathy in a white-tailed deer (Odocoileus virginianus). Journal of Veterinary Diagnostic Investigation. 21:167-170, 2009. [View publication

Madson DM, Opriessnig T: Multicentric T-cell lymphosarcoma in a white-tailed deer. Journal of Wildlife Disease. 45:791-794, 2009

 

Madson DM, Ramamoorthy S, Kuster C, Pal N, Meng XJ, Halbur PG, Opriessnig T: Infectivity of porcine circovirus type 2 DNA present in semen of experimentally infected boars. Journal of Veterinary Research. 40:10, 2009. [View publication]

 

 

 

Opriessnig T, Patterson A, Jones, Juhan N, Meng XJ, Halbur P: Susceptibility of three different mouse (Mus musculus) lines to porcine circovirus type 2 infection and associated lesions. The Canadian Journal of Veterinary Research. 73:81-86, 2009.