Dr. Petersen’s Research Interests
 • Investigation of host-pathogen interaction between the murine or canine immune system/dendritic cells    and Leishmania species.
• Characterization of key signaling events required to induce clearance of disease vs. chronicity

• Understanding of processing of and immune responses to carbohydrates

• Development of diagnostics and epidemiological studies of Brucella canis

•Prevention of Infectious Diseases in kennel/animal shelter settings

2005-present   Co-major Professor, Maddie’s Shelter Animal Medicine course, VCS 305, Iowa State University, College of Veterinary Medicine.  Teach four hour long lectures on shelter design, zoonoses, infection control in animal shelters and disaster medicine.

2007-present   Guest Lecturer, Medical Immunology, BBMB 615,  Iowa State University, College of Liberal Arts and Sciences.  Teach hour long lecture on Immunologic tolerance.

2005-present   Guest Lecturer, Zoonoses, VMPM 536, Iowa State University, College of                                      Veterinary Medicine.  Teach Cryptosporidiosis, Giardiasis and Trypanosomiasis.

2004 - Ph.D. (Immunology and Infectious Diseases), Harvard School of Public Health, Boston, MA 02115
1998 - D.V.M., Cornell University, Ithaca, NY 14853
1994 - B.A. (Biology) with departmental honors, Johns Hopkins University, Baltimore, MD 21218

1.  Mukbel, R. M., Petersen C. A., and Jones D. E. (2006) “Soluble factors from Leishmania major-specific CD4⁺ T cells and B cells limit L. amazonensis amastigote survival within infected macrophages.”  Microbes Infect., Vol 8(9-10), 2547-2555.  (PMID: 16934514- free online).

2.   Mukbel R.M., Patten C., Ghosh, M, Gibson-Corley, K, Petersen C. and Jones D.E. (2007) “Macrophage killing of Leishmania amazonensis amastigotes requires both nitric oxide and superoxide.” Am. J. Trop. Med. Hygiene, Vol 76(4), 669-675.  (PMID: 17426168- Free online).

3.   Fisch, S., Grey, S, Heymans, S, Wang, B, Haldar, S, Pfister, O, Cui, L, Kumar, A, Lin, Z, Sen-Banerjee, S, Das, H,    Petersen C.A., Mende, U, Burleigh, B.A., Zhu, Y, Pinto, Y, Liao, R, and Jain M.K. (2007) “The Kruppel-like factor KLF15 is a novel regulator of cardiomyocyte hypertrophy.”  Proc. Nat. Acad. Sci., Vol 104, 7074-7079.  (PMC1855421).

4.   Gibson-Corley, K. N., Hostetter, J.M., Hostetter, S.J., Mullin, K., Ramer-Tait, A.E., Boggiatto, M.P., Petersen, C.A. (2008) “Disseminated Leishmania infantum Infection in Two Sibling Foxhound Dogs from Potential Vertical Transmission.”  Can. Vet. J., Vol. 49, 1005-1008.  (PMC2553493).

5.   Boggiatto, M. P., Ghosh, M., Gibson-Corley, K. N., Jie, F., Ramer-Tait, A. E., Jones, D. E., Petersen, C. A.  (2009) “Altered dendritic cell phenotype in response to L. amazonensis is mediated by MAP kinase ERK.”  Am. J. Path., Vol. 174(5), 1818-1826. (PMC2671270).

6.  Petersen, C.A.  (2009) “New means of Canine Leishmaniasis transmission in North America; the possibility of transmission to humans still unknown.”  Interdisc. Perspect. Infect. Dis., Article ID 802712, 5 pages. (doi:10.1155/2009/802712).  (PMC2695953).

7.  Petersen, C.A.  (2009) “Leishmaniasis: An Emerging Disease Found in Companion Animals in the United States.” Top. Comp. An. Med., Nov; Vol. 24(4),182-8.  (PMC2805016 [Available on 2010/11/1]).

8.  Petersen, C.A., Barr, S. C., (2009) “Canine Leishmaniasis in North America: Emerging or Newly Recognized?”  In:  Vet Clin. of N. Am.; Small An. Pract., Elsevier publishing, edited by Lindsey, D and Zajac, A, Nov; 39(6):1065-74, vi. (PMC2824922 [Available on 2010/11/1]).

9. Boggiatto, M.P., Ramer-Tait, A.E., Gallup, J., Gibson-Corley, K.N., Metz, K., Kramer, E.E., Hostetter, J.M., Jones, D.E., Petersen, C.A. (2010) “Immunologic indicators of clinical progression during canine Leishmania infantum infection.” Clin. Vacc. Immunol., Vol. 17(2), 267-73. (PMC2815526).

10.  Gibson-Corley K.N., Boggiatto P.M., Petersen C.A., Jones D.E.  (2010) Co-infection with Leishmania major and Leishmania amazonensis in Two Murine Models; a role for B cells in the Cell-Mediated Immune Response.  Inter.J. Parasit., Vol. 40,157-161. (PMC2814795 [Available on 2011/2/1])

11.  E. Song, A. Osanya, P. Boggiatto, C. Petersen and N. Pohl. (2010) “Synthesis of multivalent Leishmania-associated capping carbohydrates and evaluation of structure-dependent immune responses.”   Journal of the American Chemical Society, Vol. 132 (33): 11428-30. (PMC Journal- in process)

Organized and chaired first annual Biological Sciences in Public Health Alumni Career Panel and Career Mentoring Day, Harvard School of Public Health, April 18, 2003.  

2006-present Volunteer Veterinarian, United Animal Nations, Emergency Animal Rescue Service. Responded to Louisiana post-hurricanes Katrina and Rita, 2005.

Coordinated symposium for Annual meeting of the American Society of Tropical Medicine and Hygiene, Atlanta, GA, Nov. 2006, on elimination of Leishmania infantum from US foxhounds, raised $4000 total honoraria for 5 speakers.

Coordinated Breeders symposium sponsored by the American Kennel Club Canine Health Foundation held at ISU CVM, Ames, IA, Nov. 17-18, 2007, on important health topics for dog breeders, 60 attendees, and 10 speakers.   Repeated success in June of 2010.

2007- 2010 Co-chairman (2008-2010) Student Faculty Relations Committee, CVM, ISU.

2008-present Volunteer Veterinarian, Iowa Veterinary Rapid Response Team. Responded to Cedar Rapids, IA post-flooding, 2008. Helped coordinate ISU CVM response to disaster.

2003-2007 NIH Health Disparities Scholar.

2006-2007, President, Veterinary Honor society, Phi Zeta, gamma chapter, Iowa State University.

2004-present, member Veterinary Honor society, Phi Zeta, gamma chapter, Iowa State University.

1998 Leonard Pearson Veterinary Prize, for professional and academic leadership, Cornell University.

Inaugural International Society for Companion Animal Infectious Diseases Symposium invited speaker, Toulouse, France, 2010.

American Association for the Advancement of Science

American Society of Microbiologists

American Society of Parasitologists

American Society for Tropical Medicine and Hygiene

American Veterinary Medical Association

Association of Shelter Veterinarians

Iowa Veterinary Medical Association