Qijing Zhang
 |
Qijing Zhang
BVsc, MS, PhD
Professor, Frank Ramsey Endowed Chair, and Departmental Officer of Graduate Education
Vet Microbiology & Preventive Medicine
(515) 294-2038
1116 Vet Med
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Expertise / Research Area
Food safety; antibiotic resistance; bacterial genetics; pathogen-host interactions; prevention and control of infectious diseases
Teaching
VMPM 586: Medical Bacteriology
Objectives: 1) Develop an understanding of pathogenic bacteria that cause infectious diseases in human beings but do not have enough veterinary importance to warrant coverage in VMPM 386; 2) Explore topics currently of high interest in human and veterinary bacteriology; 3) Develop an understanding of and ability to critique current research relevant to the study of pathogenic bacteria; and 4) Design and present an original research proposal.
Education
B.V.Sc Shandong Agricultural University (China) 1983 Vet Medicine
M.S. National Inst. Veterinary Biologics (China) 1986 Vet Microbiology
Ph.D. Iowa State University 1994 Immunobiology
Postdoc University of Missouri-Columbia 1994-1997 Molecular Microbiology
Selected Publications
Han, Jing, Orhan Sahin, Yi-Wen Barton, and Qijing Zhang. 2008. Key role of Mfd in the development of fluoroquinolone resistance in Campylobacter. PLoS Pathog 4(6): e1000083. doi:10.1371/journal.ppat.1000083.
Baoqing Guo, Ying Wang, Feng Shi, Yi-Wen Barton, Paul Plummer, Donald L. Reynolds, Dan Nettleton, Tara Grinnage-Pulley, Jun Lin and Qijing Zhang. 2008. CmeR functions as a pleiotropic regulator and is required for optimal colonization of Campylobacter jejuni in vivo. J. Bact. 190:1879-1890.
Jeon Byeonghwa, Wayne Muraoka, Qijing Zhang. 2008. Role of Cj1211 in natural transformation and emergence of antibiotic resistance in Campylobacter jejuni. Antimicrob. Agents Chemother. 52:2699-2708.
Orhan Sahin, Paul J. Plummer, Dianna M. Jordan, Kapllan Sulaj, Sonia Pereira, Suelee Robbe-Austerman, Liping Wang, Michael J. Yaeger, Lorraine J. Hoffman, and Qijing Zhang. 2008 Emergence of a tetracycline-resistant Campylobacter jejuni clone associated with ovine abortion in the United States. J. Clin. Microbiol. 46:1663-1671.
Gu Rouyu, Chih-Chia Su, Feng Shi, Ming Li, Gerry McDermott, Qijing Zhang and Edward W. Yu. 2007. Crystal Structure of the transcriptional regulator CmeR from Campylobacter jejuni. J. Mol. Biol. 372:583-593.
Lin Jun, Meiguan Yan, Orhan Sahin, Sonia Pereira, Yun-Juan Chang, and Qijing Zhang. 2007. Effect of macrolide usage on the emergence of erythromycin-resistant Campylobacter in chickens. Antimicrob. Agents Chemother. 51: 1678-1686.
Jeon B. and Qijing Zhang. 2007. Cj0011c, a periplasmic single- and double-stranded DNA binding protein, contributes to natural transformation in Campylobacter jejuni. J. Bact. 189:7399-7407.
Yan, M., O, Sahin, J. Lin, and Q. Zhang. 2006. Role of the CmeABC efflux pump in the emergence of fluoroquinolone-resistant Campylobacter under selection pressure. J. Antimicrobial. Chemother. 58:1154-1159.
Zhang, Q., O. Sahin, P. F. McDermott, and S. Payot. 2006. Fitness of antimicrobial resistant Campylobacter and Salmonella. Microbes Infect.
Lin, J., M. Akiba, O. Sahin, and Q. Zhang. 2005. CmeR functions as a transcriptional repressor for the multidrug efflux pump CmeABC in Campylobacter jejuni. Antimicrob. Agents Chemother. 49:1067-1075.
Luo N, S. Pereira, O. Sahin, J. Lin, S. Huang, L. Michel, and Q. Zhang. 2005. Enhanced in vivo fitness of fluoroquinolone-resistant Campylobacter jejuni in the absence of antibiotic selection pressure. Proc. Natl. Acad. Sci. U. S. A. 102:541-546.
Raphael, B. H., S. Pereira, E. Dave, G. A. Flom, Q. Zhang, J. M. Ketley, and M. E. Konkel. 2005. The Campylobacter jejuni response regulator, CBbrR, modulates sodium deoxycholate resistance and chicken colonization. J. Bact. 187(11):3662-70.
Lin, J., C. Cagliero, B. Guo, Y-W., Barton, M. C. Maurel, S. Payot, and Q. Zhang. 2005. Bile salts modulate the expression of multidrug efflux pump CmeABC in Campylobacter jejuni. J. Bacteriol. 187:7417-7424.
Leadership
Departmental Officer of Graduate Education, Veterinary Microbiology and Preventivie Medicine
Chair, CVM International Development Committee
Chair, Division Z (Animal Health), American Society for Microbiology, 2009-2010
Editorial Board: Avian Diseases
Applied and Environmental Microbiology
Honors & Awards
Endowed Frank K. Ramsey Chair in Veterinary Medicine, Iowa State University, since 2003.
Pfizer Award for Research Excellence, Iowa State University, 2007
Memberships
American Society for Microbiology
Conference of Research Workers in Animal Diseases
American Association for the Advancement of Science
American Veterinary Medical Association
American Association of Avian Pathologists
