The main interest of our laboratory is in the areas of innate immunology and diseases of aquatic organisms, but we also perform research in mammalian and bird innate immunology, as well as aquatic ecosystem health. Some of current and past research projects include: dietary immunomodulation of β-glucans and yeast compounds in fish; neutrophil extracellular trap formation in fish, birds and mammals; heterophil function in chickens exposed to Salmonella enteritidis infection; effects of tulathromycin on bovine neutrophils; development of GFP transgenic zebrafish neutrophil research model and it’s applications in information-rich in vivo imaging; effects of field runoff on neutrophil function in fish and development of GIS flow path analysis model; and stress effects on immunology of fish species of special concern. I am also a member of the teams working on development of the National Veterinary Accreditation Program education modules for aquatic animals, and veterinary aquaculture biosecurity certification.

Member of Interdepartmental Graduate programs in Immunobiology, Toxicology, and Neuroscience

Member of Graduate College in areas of: Biomedical Sciences; Fisheries Biology; Immunobiology; Toxicology; Veterinary Microbiology; and Veterinary Preventive Medicine

Jovanović B., Goetz, F. W., Goetz G. W., and Palić, D. (2011). Different Immunological Stimuli Can Change Gene Expression and Neutrophil Function in Fathead Minnow (Pimephales promelas Rafinesque, 1820). Journal of Fish Biology (accepted).

Palić, D., Beck, L. S., Palić, J., and Andreasen C. B. (2011). Use of Rapid Cytochemical Staining to Characterize Fish Blood Leukocytes in Species of Special Concern and Determine Potential for Neutrophil Functional Testing. Fish and Shellfish Immunology. doi:10.1016/j.fsi.2010.12.024.

Jovanović B., Anastasova, L. Rowe W. E., Zhang, Y., Clapp A. R., and Palić, D. (2011). Effects of Nanosized Titanium Dioxide on Innate Immune System of Fathead Minnow (Pimephales promelas Rafinesque, 1820). Ecotoxicology and Environmental Safety, doi:10.1016/j.ecoenv.2010.10.017

Jovanović B., Rowe W. E., Anastasova, L., and Palić, D. (2011). Hydroxylated Fullerenes Inhibit Neutrophil Function in Fathead Minnow (Pimephales promelas Rafinesque, 1820). Aquatic Toxicology 101, 474-482.

Redmond, S.B., Tell, R.M., Coble, D., Mueller, C., Palić, D., Andreasen, C.B., and Lamont, S.J. (2010). Differential splenic cytokine responses to dietary immune modulation by diverse chicken lines. Poultry Science 89, 1635-1641.

Redmond, S. B., Chuammitri, P. Claire B. Andreasen, C. B., Palić, D., and Lamont, S. J. (2009). Chicken Heterophils from Commercially Selected and Non-selected Genetic Lines Express Cytokines Differently After in vitro Exposure to Salmonella enteritidis. Veterinary Immunology and Immunopathology 132, 129-134.

Chuammitri, P., Ostojić, J., Andreasen, C. B., Redmond, S. B., Lamont, S. J., and Palić, D. (2009). Chicken Heterophil Extracellular Traps (HETs): Novel defense mechanism of chicken heterophils.Veterinary Immunology and Immunopathology 129, 126-131.

Palić, D., Ostojić, J., Andreasen, C. B. and Roth, J. A. (2007). Fish cast NETs: Neutrophil Extracellular Traps are Released from Fish Neutrophils. Developmental and Comparative Immunology 31, 805-816.

Palić, D., Helland, L., Pedersen, B., Pribil, J., Grajeda, R., Loan-Wilsey, A. and Pierce, C. L. (2007). Fish Assemblages of the Upper Little Sioux River Basin, Iowa, USA: Relationships with Stream Size and Comparison with Historical Assemblages. Journal of Freshwater Ecology 22(1), 69-79.

Palić, D., Andreasen, C. B., Ostojić, J., Tell, R. M. and Roth, J. A. (2007). Zebrafish (Danio rerio) Whole Kidney Assays to Measure Degranulation of Primary Granules and Neutrophil Extracellular Trap Release. Journal of Immunological Methods 319, 87-97.

Starling, D. E., Palić, D. and Scarfe, A. D. (2007). Refinement and use of Certificates of Veterinary Inspection (Health Certificates) for Optimal Assurance of Disease Freedom in Aquatic Animals. In Dodet B., the OIE Scientific & Technical Department (eds): The OIE Global Conference on Aquatic Animal Health. Developments in Biologicals 129, 103‑113.

Palić, D., Andreasen, C. B., Herolt, D. M., Menzel,B. W. and Roth, J. A. (2006). Immunomodulatory Effects of β-glucan on Neutrophil Function in Fathead Minnows (Pimephales promelas Rafinesque, 1820). Developmental and Comparative Immunology 30(9), 817-830.

Palić, D., Herolt, D. M., Andreasen, C. B., Menzel,B. W. and Roth, J. A. (2006). Anesthetic Efficacy of Tricaine Methanesulphonate, Metomidate and Eugenol: Effects on Plasma Cortisol Levels and Neutrophil Function in Fathead Minnow (Pimephales promelas Rafinesque, 1820). Aquaculture 254(1-4), 675-685.

Palić, D., Andreasen, C. B., Menzel,B. W. and Roth, J. A. (2005). A rapid, direct assay to measure degranulation of primary granules in neutrophils from kidney of fathead minnow (Pimephales promelas Rafinesque, 1820). Fish and Shellfish Immunology 19(3), 217-227.

Palić, D., Andreasen, C. B., Frank, D. E., Menzel,B. W. and Roth, J. A. (2005). Gradient separation and cytochemical characterization of neutrophils from kidney of fathead minnow (Pimephales promelas Rafinesque, 1820). Fish and Shellfish Immunology 18(3), 263-267.