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Nancy Cornick

Nancy Cornick
Nancy Cornick

Associate Professor
Vet Microbiology & Preventive Medicine
(515) 294-6499
2130 Vet Med
Expertise / Research Area

Pre-harvest food safety, bacterial colonization mechanisms, zoonotic transmission of bacterial pathogens, pathogenesis of enteric E. coli diseases and the microbial ecology of gastrointestinal systems.  Currently projects include defining colonization mechanisms used by E. coli O157:H7 in ruminants and understanding the pathogenesis of Shiga toxin-producing E. coli infections.




Micro 553. Pathogenic microorganisms.   Fall; 1 credit.  Review and comparison/contrast of common bacterial pathogens of plants and animals and their mechanisms of virulence, including toxins, protein secretion, host invasion and iron acquisition strategies.  An overview of eukaryotic cell biology that is relevant to pathogenesis will also be included.

VMPM 525.  Intestinal microbiology. Alt. Spring, offered 2012; 3 credits. Overview of the role of commensal microbiota in the maintenance of health and well-being of vertebrates.  Topics include diversity of digestive systems, microbial diversity/function, innate immune development, community interactions and metabolic diseases associated with alterations of the microbiome.

Work-in-progress.  WIP is a weekly presentation of current research by graduate students and post docs working in the areas of microbiology, immunology and infectious disease at the College of Veterinary Medicine.



MS & PhD Microbiology,  Iowa State University


Educational interests. Graduate education in microbiology, microbial pathogenesis, and food safety.  Development of critical thinking skills, collaborative learning and delivery of educational material in blended classrooms and on-line settings. 


Selected Publications

Cornick, NA, I Matise, JE Samuel, BT Bosworth and HW Moon. 2000. Shiga toxin-producing Escherichia coli infection: temporal and quantitative relationships among colonization, toxin production, and systemic disease. J. Infect. Dis. 181:242-251.

Cornick, NA, SL Booher, TA Casey and HW Moon. 2000. Persistent colonization of sheep by Escherichia coli O157:H7 and other E. coli pathotypes. Appl. Environ. Microbiol. 66:4926-4934

Pruimboom-Brees, IM, TW Morgan, MR Ackerman, ED Nystrom, JE Samuel, NA Cornick and HW Moon. 2000. Cattle lack receptors to Escherichia coli O157:H7 Shiga toxin.  Proc. Nat. Acad. Sci. USA  97:10325-10329. 

Cornick, NA, SL Booher and HW Moon. 2002. Intimin facilitates colonization by Escherichia coli O157:H7 in ruminants. Infect. Immun. 70:2704-2707.

Booher, SL, NA Cornick, and HW Moon. 2002. Persistence of Escherichia coli O157:H7 in swine. Vet. Microbiol. 89:69-81.

Cornick, NA, and AF Helgerson. 2004. Transmission and infectious dose of E. coli O157:H7 for swine. Appl. Environ. Microbiol. 70:5331-5335.

Cornick, NA, AF Helgerson, V Mai, JM Ritchie, DWK Acheson. 2006. In vivo transduction of stx-encoding phage in ruminants. Appl. Environ. Microbiol. 72:5086-5088.

Helgerson, AF, V Sharma, AM Dow, R Schroeder, K Post and NA Cornick. 2006. Edema disease caused by a clone of Escherichia coli O147:H17. J. Clin. Microbiol. 44:3074-3077.

Cornick, NA, AF Helgerson and V Sharma. 2007. Stx-encoding phage does not facilitate colonization of Escherichia coli O157:H7 in sheep. Appl. Environ. Microbiol. 73:344-346.

VuKhac, H and NA Cornick. 2008. Prevalence and genetic profiles of Shiga toxin-producing Escherichia coli strains isolated from buffaloes, cattle and goats in central Viet Nam. Vet. Microbiol. 126:356-363.

Cornick, NA and H. VuKhac. 2008. Indirect transmission of Escherichia coli O157:H7 occurs readily amongst swine, but not amongst sheep. Appl. Environ. Microbiol.  74:2488-2491.

Cornick, NA.  2010. Tylosin and chlorotetracycline decrease the duration of fecal shedding of Escherichia coli O157:H7 in swine.  Vet. Microbiol. 143:417-419.

Puttamreddy, S, NA Cornick, and FC Minion.  2010.  Genome-wide transposon mutagenesis reveals a role for pO157 genes in biofilm development in E. coli O157:H7 EDL933. Infect. Immun. 78:2377-2384.

Schwarte, KA, JL Kovar, DG Morrical, SM Ensley, KJ Yoon, NA Cornick, Y Cho and JB Russell.  2011.  Grazing management effects on sediment, phosphorus and pathogen loading of streams in cool-season grass pastures. J. Environ. Quality,  40:1303-1313.





Chair, Institutional Biosafety Committee, 2006-present

DOGE, Veterinary Microbiology, 2012-present

Chair, Division Z – Amer. Society for Microbiology, 2007


American Society for Microbiology