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Annette M O'Connor

Annette O'Connor
Annette O'Connor

BVSc, MVSc, DVSc, FACVSc (Epidemiology)

Professor
Vet Diagnostic & Production Animal Med
(515) 294-5012
VMRI Bld 4
Expertise / Research Area

Dr. O’Connor is a veterinary epidemiologist, and she has applied the principles of that discipline to a diverse set of fields, including livestock diseases, food-borne pathogens of animal proteins and veterinary public health. The main area of focus of Dr. O’Connor’s research has been to understand how researchers can use study design and research synthesis methodologies to translate primary research findings into decision support tools for agencies. Dr. O’Connor was been funded for this work by groups such as USDA, the National Pork Board and the European Union Food Safety Authority. Topic’s evaluated include pre-harvest food safety interventions, post harvest interventions, zoonotic pathogens and the impact of proximity to confined animal operations on community health. This work includes understanding how standards of evidence translate from human medicine to food safety. Primarily this work has focused on how to adopt and adapt the systematic review methodology and meta-analysis used in clinical medicine to veterinary science and food safety.  This area has resulted in several papers about how to review observational studies and randomized controlled trials in veterinary science and food safety. Further, this body of work has resulted in the production of the REFLECT statement (www.reflect-statement.org  Reporting guidelinEs For randomized controlLed trials for livEstoCk and food safeTy.) The REFLECT statement is guide for authors, reviewers and editors on how to report intervention studies in a manner that increases their utility to end users including practitioners and risk assessors.  The acronym REFLECT incorporates the aim of the reporting guideline i.e., the publication should reflect what was done.

 

In the area of work that relates to the epidemiology of infectious disease that affect livestock populations, Dr. O’Connors work relates primarily  to 1) understanding causes of disease and 2) comparative effectiveness of interventions.  Dr. O'Connor has focused on understanding the epidemiology and control of Pinkeye in beef cattle. Studies have included observational studies that evaluate the role of putative causal organism in Pinkeye and randomized field trials that evaluate the efficacy of vaccine designed to prevent Pinkeye occurrence.  Consistent with the theme of increasing translation of primary research for decision makers Dr O'Connor has also co-authored several reviews evaluating the treatment and control of Pinkeye. Another organism of focus for Dr O'Connor has been the epidemiology of Salmonella in pork with emphasis on understanding pre-harvest control approaches.   Dr O'Connor has worked on several primary research studies that have evaluated the methods of detecting farms with a high risk of carrying Salmonella spp. into the slaughterhouse. Again, Dr O'Connor has also co-authored several reviews evaluating the treatment and control of Salmonella in the pre-harvest environment. Dr. O’Connor also has many collaborative projects such as projects on MRSA, PCV2, and PRRS in swine, campylobacter in poultry, and brucellosis in sheep.  The combined impact of this work has been to provide producers, veterinarians, government agencies and industry groups with independent advice about the efficacy of relevant interventions.

 

Dr. O’Connor received a Bachelor Of Veterinary Science (BVSc) from the University of Sydney in 1993, a Masters of Veterinary Science (MVSc) from the University of Queensland in 1997 and a Doctoral of Veterinary Science (DVSc) from the University of Guelph in 2001.  In  2009, Dr. O’Connor was admitted as a Fellow of Epidemiology to the Australian and New Zealand College of Veterinary Scientists. Dr. O’Connor is Professor of Epidemiology at Iowa State University. Dr. O’Connor teaches epidemiology methods and inference in the Preventive Veterinary Medicine Program at Iowa State University the MPH program at the College of Public Health at the University of Iowa.  Dr. O’Connor frequently teaches workshops of review methodologies or approaches to outcomes research and comparative effectiveness.

 

Teaching

Dr O'Connor teaches primarily in the graduate curriculum. She teaches an introductory course for epidemiologists, and a course in applied logistic regression methods. Dr. O'Connor is also the Director of a Graduate Certificate in Veterinary Preventive Medicine. This 15 credit academic program is designed to be taken by distance for professionals working in livetsock health and food safety. Students who complete the certifiacte may aslo be able to transfer to the Masters program.

Education

EDUCATION
BVSc                                                                University of Sydney    1993
MVSc                                                          University of Queensland    1997
DVSc                                                                University of Guelph     2000
Member of Australian College of Veterinary Scientists (Epidemiology)       2003
Fellow of Australian College of Veterinary Scientists (Epidemiology)          2009


 

Selected Publications

PUBMED SEARCH

"O'Connor AM"[Author] AND (animal OR campylobacter OR reporting OR livestock OR Salmonella OR Swine OR pork OR beef OR Cattle)

 

1.

Effect of oral meloxicam on health and performance of beef steers relative to bulls castrated upon arrival at the feedlot.

Coetzee JF, Edwards LN, Mosher RA, Bello NM, O'Connor AM, Wang B, Kukanich B, Blasi DA.

J Anim Sci. 2011 Sep 30. [Epub ahead of print]

PMID:
21965454
[PubMed - as supplied by publisher]
2.

Descriptive epidemiology of Moraxella bovis, Moraxella bovoculi and Moraxella ovis in beef calves with naturally occurring infectious bovine keratoconjunctivitis (Pinkeye).

O'Connor AM, Shen HG, Wang C, Opriessnig T.

Vet Microbiol. 2011 Sep 16. [Epub ahead of print]

PMID:
21962410
[PubMed - as supplied by publisher]
3.

Salmonella enterica in Swine Production: Assessing the Association between Amplified Fragment Length Polymorphism and Epidemiological Units of Concern in Swine Production.

Wang B, Wang C, McKean JD, Logue CM, Gebreyes WA, Tivendale KA, O'Connor AM.

Appl Environ Microbiol. 2011 Sep 23. [Epub ahead of print]

PMID:
21948822
[PubMed - as supplied by publisher]
4.

Use of bioinformatic SNP predictions in differentially expressed genes to find SNPs associated with Salmonella colonization in swine.

Uthe JJ, Qu L, Couture O, Bearson SM, O'Connor AM, McKean JD, Torres YR, Dekkers JC, Nettleton D, Tuggle CK.

J Anim Breed Genet. 2011 Oct;128(5):354-65. doi: 10.1111/j.1439-0388.2011.00935.x. Epub 2011 Jun 17.

PMID:
21906181
[PubMed - in process]
5.

Integrating comparative expression profiling data and association of SNPs with Salmonella shedding for improved food safety and porcine disease resistance.

Uthe JJ, Bearson SM, Qu L, Dekkers JC, Nettleton D, Rodriguez Torres Y, O'Connor AM, McKean JD, Tuggle CK.

Anim Genet. 2011 Oct;42(5):521-34. doi: 10.1111/j.1365-2052.2010.02171.x. Epub 2011 Mar 7.

PMID:
21906103
[PubMed - in process]
6.

Development and evaluation of a multiplex real-time PCR assay for the detection and differentiation of Moraxella bovis, Moraxella bovoculi and Moraxella ovis in pure culture isolates and lacrimal swabs collected from conventionally raised cattle.

Shen HG, Gould S, Kinyon J, Opriessnig T, O'Connor AM.

J Appl Microbiol. 2011 Aug 9. doi: 10.1111/j.1365-2672.2011.05123.x. [Epub ahead of print]

PMID:
21827584
[PubMed - as supplied by publisher]
7.

What is the evidence?

O'Connor AM, Gould SA, Coetzee JF, Kreuder AJ, Plummer PJ.

J Am Vet Med Assoc. 2011 Aug 1;239(3):314-6. No abstract available.

PMID:
21801043
[PubMed - in process]
8.

Using the systematic review methodology to evaluate factors that influence the persistence of influenza virus in environmental matrices.

Irwin CK, Yoon KJ, Wang C, Hoff SJ, Zimmerman JJ, Denagamage T, O'Connor AM.

Appl Environ Microbiol. 2011 Feb;77(3):1049-60. Epub 2010 Dec 10. Review.

PMID:
21148699
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Reporting of methodological features in observational studies of pre-harvest food safety.

Sargeant JM, O'Connor AM, Renter DG, Kelton DF, Snedeker K, Wisener LV, Leonard EK, Guthrie AD, Faires M.

Prev Vet Med. 2011 Feb 1;98(2-3):88-98. Epub 2010 Nov 20.

PMID:
21095033
[PubMed - indexed for MEDLINE]
10.
11.

Characteristics of clinical trials assessing antimicrobial treatment of bovine respiratory disease, 1970-2005.

O'Connor AM, Wellman NG, Rice M, Funk L.

J Am Vet Med Assoc. 2010 Sep 15;237(6):701-5. Review.

PMID:
20839994
[PubMed - indexed for MEDLINE]
12.

The quality of reporting and publication status of vaccines trials presented at veterinary conferences from 1988 to 2003.

Brace S, Taylor D, O'Connor AM.

Vaccine. 2010 May 28. [Epub ahead of print]

PMID:
20685270
[PubMed - as supplied by publisher]
13.

The quality of reporting and publication status of vaccines trials presented at veterinary conferences from 1988 to 2003.

Brace S, Taylor D, O'Connor AM.

Vaccine. 2010 Jul 19;28(32):5306-14.

PMID:
20665976
[PubMed - indexed for MEDLINE]
14.

The change in prevalence of Campylobacter on chicken carcasses during processing: a systematic review.

Guerin MT, Sir C, Sargeant JM, Waddell L, O'Connor AM, Wills RW, Bailey RH, Byrd JA.

Poult Sci. 2010 May;89(5):1070-84. Review.

PMID:
20371862
[PubMed - indexed for MEDLINE]
Free Article
15.

The association between proximity to animal feeding operations and community health: a systematic review.

O'Connor AM, Auvermann B, Bickett-Weddle D, Kirkhorn S, Sargeant JM, Ramirez A, Von Essen SG.

PLoS One. 2010 Mar 10;5(3):e9530. Review.

PMID:
20224825
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The REFLECT statement: reporting guidelines for randomized controlled trials in livestock and food safety: explanation and elaboration.

Sargeant JM, O'Connor AM, Gardner IA, Dickson JS, Torrence ME, Dohoo IR, Lefebvre SL, Morley PS, Ramirez A, Snedeker K.

J Food Prot. 2010 Mar;73(3):579-603.

PMID:
20202349
[PubMed - indexed for MEDLINE]
17.

Sub-iliac lymph nodes at slaughter lack ability to predict Salmonella enterica prevalence for swine farms.

Wang B, Wesley IV, McKean JD, O'Connor AM.

Foodborne Pathog Dis. 2010 Jul;7(7):795-800.

PMID:
20187754
[PubMed - indexed for MEDLINE]
18.

The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety by modifying the CONSORT statement.

O'Connor AM, Sargeant JM, Gardner IA, Dickson JS, Torrence ME; Consensus Meeting Participants, Dewey CE, Dohoo IR, Evans RB, Gray JT, Greiner M, Keefe G, Lefebvre SL, Morley PS, Ramirez A, Sischo W, Smith DR, Snedeker K, Sofos J, Ward MP, Wills R.

Zoonoses Public Health. 2010 Mar;57(2):95-104. Epub 2010 Jan 12.

PMID:
20070653
[PubMed - indexed for MEDLINE]
19.

The REFLECT statement: reporting guidelines for Randomized Controlled Trials in livestock and food safety: explanation and elaboration.

Sargeant JM, O'Connor AM, Gardner IA, Dickson JS, Torrence ME; Consensus Meeting Participants.

Zoonoses Public Health. 2010 Mar;57(2):105-36. Epub 2010 Jan 12.

PMID:
20070652
[PubMed - indexed for MEDLINE]
20.

The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety.

O'Connor AM, Sargeant JM, Gardner IA, Dickson JS, Torrence ME, Dewey CE, Dohoo IR, Evans RB, Gray JT, Greiner M, Keefe G, Lefebvre SL, Morley PS, Ramirez A, Sischo W, Smith DR, Snedeker K, Sofos JN, Ward MP, Wills R; Consensus Meeting Participants.

J Food Prot. 2010 Jan;73(1):132-9.

PMID:
20051216
[PubMed - indexed for MEDLINE]
21.

The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety.

O'Connor AM, Sargeant JM, Gardner IA, Dickson JS, Torrence ME, Dewey CE, Dohoo IR, Evans RB, Gray JT, Greiner M, Keefe G, Lefebvre SL, Morley PS, Ramirez A, Sischo W, Smith DR, Snedeker K, Sofos J, Ward MP, Wills R; Steering Committee.

J Vet Intern Med. 2010 Jan-Feb;24(1):57-64.

PMID:
20002546
[PubMed - indexed for MEDLINE]
22.

The REFLECT statement: methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety.

O'Connor AM, Sargeant JM, Gardner IA, Dickson JS, Torrence ME, Dewey CE, Dohoo IR, Evans RB, Gray JT, Greiner M, Keefe G, Lefebvre SL, Morley PS, Ramirez A, Sischo W, Smith DR, Snedeker K, Sofos J, Ward MP, Wills R.

Prev Vet Med. 2010 Jan 1;93(1):11-8. Epub 2009 Nov 18.

PMID:
19926151
[PubMed - indexed for MEDLINE]
23.

A randomized and blinded field trial to assess the efficacy of an autogenous vaccine to prevent naturally occurring infectious bovine keratoconjunctivis (IBK) in beef calves.

Funk L, O'Connor AM, Maroney M, Engelken T, Cooper VL, Kinyon J, Plummer P.

Vaccine. 2009 Jul 23;27(34):4585-90. Epub 2009 Jun 14.

PMID:
19531391
[PubMed - indexed for MEDLINE]
24.

Intestinal cytokine mRNA expression in canine inflammatory bowel disease: a meta-analysis with critical appraisal.

Jergens AE, Sonea IM, O'Connor AM, Kauffman LK, Grozdanic SD, Ackermann MR, Evans RB.

Comp Med. 2009 Apr;59(2):153-62. Erratum in: Comp Med. 2009 Jun;59(3):220.

PMID:
19389307
[PubMed - indexed for MEDLINE]
Free PMC Article
25.

Animal welfare and epidemiology-across species, across disciplines, and across borders.

Millman ST, Johnson AK, O'Connor AM, Zanella AJ.

J Appl Anim Welf Sci. 2009;12(2):83-7. No abstract available.

PMID:
19319710
[PubMed - indexed for MEDLINE]
26.

Phenotypic characterization of cognition and social behavior in mice with heterozygous versus homozygous deletion of catechol-O-methyltransferase.

Babovic D, O'Tuathaigh CM, O'Connor AM, O'Sullivan GJ, Tighe O, Croke DT, Karayiorgou M, Gogos JA, Cotter D, Waddington JL.

Neuroscience. 2008 Sep 9;155(4):1021-9. Epub 2008 Jul 10.

PMID:
18674597
[PubMed - indexed for MEDLINE]
27.

Feeding management practices and feed characteristics associated with Salmonella prevalence in live and slaughtered market-weight finisher swine: a systematic review and summation of evidence from 1950 to 2005.

O'Connor AM, Denagamage T, Sargeant JM, Rajić A, McKean J.

Prev Vet Med. 2008 Nov 17;87(3-4):213-28. Epub 2008 Jul 30. Review.

PMID:
18667253
[PubMed - indexed for MEDLINE]
28.

Assessing the effect of sample handling on the performance of a commercial bovine viral diarrhea virus antigen-capture enzyme-linked immunosorbent assay.

Reed MC, O'Connor AM, Yoon KJ, Cooper VL.

J Vet Diagn Invest. 2008 Jan;20(1):124-6.

PMID:
18182528
[PubMed - indexed for MEDLINE]
Free Article
30.

Efficacy of vaccination to reduce Salmonella prevalence in live and slaughtered swine: a systematic review of literature from 1979 to 2007.

Denagamage TN, O'Connor AM, Sargeant JM, Rajić A, McKean JD.

Foodborne Pathog Dis. 2007 Winter;4(4):539-49. Review.

PMID:
18041963
[PubMed - indexed for MEDLINE]
31.

Disruption to social dyadic interactions but not emotional/anxiety-related behaviour in mice with heterozygous 'knockout' of the schizophrenia risk gene neuregulin-1.

O'Tuathaigh CM, O'Connor AM, O'Sullivan GJ, Lai D, Harvey R, Croke DT, Waddington JL.

Prog Neuropsychopharmacol Biol Psychiatry. 2008 Feb 15;32(2):462-6. Epub 2007 Sep 29.

PMID:
17980471
[PubMed - indexed for MEDLINE]
32.

Prevalence of calves persistently infected with bovine viral diarrhea virus in beef cow-calf herds enrolled in a voluntary screening project.

O'Connor AM, Reed MC, Denagamage TN, Yoon KJ, Sorden SD, Cooper VL.

J Am Vet Med Assoc. 2007 Jun 1;230(11):1691-6.

PMID:
17542740
[PubMed - indexed for MEDLINE]
33.

Meta-analysis of treatment of cattle with bovine respiratory disease with tulathromycin.

Wellman NG, O'Connor AM.

J Vet Pharmacol Ther. 2007 Jun;30(3):234-41. Review.

PMID:
17472655
[PubMed - indexed for MEDLINE]
34.

A review of randomized clinical trials reporting antibiotic treatment of infectious bovine keratoconjunctivitis in cattle.

O'Connor AM, Wellman NG, Evans RB, Roth DR.

Anim Health Res Rev. 2006 Jun-Dec;7(1-2):119-27. Review.

PMID:
17389059
[PubMed - indexed for MEDLINE]
35.

Methodological quality assessment of review articles evaluating interventions to improve microbial food safety.

Sargeant JM, Torrence ME, Rajić A, O'Connor AM, Williams J.

Foodborne Pathog Dis. 2006 Winter;3(4):447-56.

PMID:
17199527
[PubMed - indexed for MEDLINE]
36.

Quantity and distribution of Salmonella recovered from three swine lairage pens.

O'Connor AM, Gailey J, McKean JD, Hurd HS.

J Food Prot. 2006 Jul;69(7):1717-9.

PMID:
16865909
[PubMed - indexed for MEDLINE]
37.

Prevalence of exposure to Salmonella spp in finishing swine marketed in Iowa.

Leadership

Current service appointments

Graduate College Curriculum and Catalogue Committee (Chair)        2008-2010
Faculty Senate Curriculum and catalogue Committee (Member)        2008-2010
Graduate Council (Chair)                                                               2008-2010
Research Advisor Committee (Member)                                           2006-2010
Administrative Fellow (Advance Program)                                         2010

 

Honors & Awards

Pfizer Research Excellence Award 2008.