Nancy Cornick

PhD
Associate Professor
515-294-6499
2130 Vet Med
Education & Certifications  

MS & PhD Microbiology,  Iowa State University

 

Educational interests. Graduate education in microbiology, microbial pathogenesis, and food safety.  Development of critical thinking skills, collaborative learning and delivery of educational material in blended classrooms. 

 

Teaching  

Micro 553. Pathogenic microorganisms.   Fall; 1 credit.  Review and comparison/contrast of common bacterial pathogens of plants and animals and their mechanisms of virulence, including toxins, protein secretion, host invasion and iron acquisition strategies.  An overview of eukaryotic cell biology that is relevant to pathogenesis will also be included.

VMPM 525.  Intestinal microbiology. Alt. Springs, offered even years; 3 credits. Overview of the role of commensal microbiota in the maintenance of health and well-being of vertebrates.  Topics include diversity of digestive systems, microbial diversity/function, innate immune development, community interactions and metabolic diseases associated with alterations of the microbiome.

 

Research Focus & Interests  

Pre-harvest food safety, bacterial colonization mechanisms, zoonotic transmission of bacterial pathogens, microbial ecology of gastrointestinal systems, pathogenesis of enteric diseases caused by E. coli and Clostridium. 

 

Leadership/Committees/Council  

Chair, Institutional Biosafety Committee, 2006-2015

DOGE, Veterinary Microbiology, 2012-present

Chair, Division Z – Amer. Society for Microbiology, 2007

Memberships  

American Society for Microbiology

Selected Publications  

Full publication list on PubMed

Moon, HW, Hoffman, LJ, Cornick, NA, Booker, SL, Bosworth, BT. 1999. Prevalences of some virulence genes among Escherichia coli isolates from swine presented to a diagnostic laboratory in Iowa. Journal of Veterinary Diagnostic Investigation 11 (6), 557.

Cornick, NA, I Matise, JE Samuel, BT Bosworth and HW Moon. 2000. Shiga toxin-producing Escherichia coli infection: temporal and quantitative relationships among colonization, toxin production, and systemic disease. J. Infect. Dis. 181:242-251.

Cornick, NA, SL Booher, TA Casey and HW Moon. 2000. Persistent colonization of sheep by Escherichia coli O157:H7 and other E. coli pathotypes. Appl. Environ. Microbiol. 66:4926-4934

Pruimboom-Brees, IM, TW Morgan, MR Ackerman, ED Nystrom, JE Samuel, NA Cornick and HW Moon. 2000. Cattle lack receptors to Escherichia coli O157:H7 Shiga toxin.  Proc. Nat. Acad. Sci. USA  97:10325-10329. 

Cornick, NA, SL Booher and HW Moon. 2002. Intimin facilitates colonization by Escherichia coli O157:H7 in ruminants. Infect. Immun. 70:2704-2707.

Cornick, NA, Jelacic, S, Ciol, MA, Tarr PI. 2002. Escherichia coli O157: H7 infections: discordance between filterable fecal Shiga toxin and disease outcome. Journal of Infectious Diseases 186 (1), 57-63.

Cornick, NA, and AF Helgerson. 2004. Transmission and infectious dose of E. coli O157:H7 for swine. Appl. Environ. Microbiol. 70:5331-5335.

Jordan, DM, Cornick, NA, Torres, AG, Dean-Nystrom, EA, Kaper, JB. 2004. Long polar fimbriae contribute to colonization by Escherichia coli O157: H7 in vivo. Infection and immunity 72 (10), 6188-6171

Cornick, NA, AF Helgerson, V Mai, JM Ritchie, DWK Acheson. 2006. In vivo transduction of stx-encoding phage in ruminants. Appl. Environ. Microbiol. 72:5086-5088.

VuKhac, H and NA Cornick. 2008. Prevalence and genetic profiles of Shiga toxin-producing Escherichia coli strains isolated from buffaloes, cattle and goats in central Viet Nam. Vet. Microbiol. 126:356-363.

Puttamreddy S, NA Cornick, and FC Minion.  2010.  Genome-wide transposon mutagenesis reveals a role for pO157 genes in biofilm development in E. coli O157:H7 EDL933. Infect. Immun. 78:2377-2384.

Hostetter SJ, Helgerson AF, Paton JC, Paton AE, and Cornick NA. 2014. Therapeutic use of a receptor mimic probiotic reduces intestinal Shiga toxin levels in a piglet model of hemolytic uremic syndrome. BMC research Notes, 7:331

Edited by I Kidva, J Bannantine, B Bellaire, NA Cornick, T Nicholson, P Plummer and Q Zhang. 2016. Virulence mechanisms of bacterial pathogens. 5th ed, ASM Press