Shankumar Mooyottu

DVM, PhD, Diplomate ACVP
Assistant Professor
2716 Vet Med


    Education & Certifications  

    2018    Diplomate, American College of Veterinary Pathologists

    2017    MS (Pathobiology - Veterinary Anatomic Pathology), University of Connecticut, Storrs, CT

    2016    PhD (Animal Science – Microbiology), University of Connecticut, Storrs, CT

    2010    MVSc (Veterinary Pathology), Indian Veterinary Research Institute, Bareilly, UP, India

    2008    BVSc (DVM), Kerala Agricultural University, Thrissur, Kerala, India

    • Coordinator, Anatomic Pathology Residency Program
    • Instructor-in-charge, Principles of Pathology (VPTH 503)
    • Instructor, Autopsy Practicum (VPTH 456)
    • Instructor, Systemic Pathology (VPTH 570) - Gastrointestinal Pathology
    Research Focus & Interests  
    • Novel non-antibiotic strategies against important enteric diseases such as C. difficile infection in humans and animals with special reference to gut-microbiome and dysbiosis.
    • Effect of dysbiosis-associated clostridial metabolites on the gut-brain and gut-liver axes.
    • Molecular epidemiology and zoonotic transmission of community-associated C. difficile infection.
    Selected Publications  
    • Vinithakumari, A.A., Padhi, P., Hernandez, B., Lin, S.J.H., Dunkerson-Kurzhumov, A., Showman, L., Breitzman, M., Stokes, C., Sulaiman, Y., Tangudu, C. and Mooyottu. S. (2022). Clostridioides difficile infection dysregulates brain dopamine metabolism. Microbiology Spectrum. e00073-22
    • Wherry, T. L., Dassanayake, R., Casas, E., Mooyottu, S., Bannantine, J. P., & Stabel, J. R. (2022). Exogenous Vitamin D3 Modulates Response of Bovine Macrophages to Mycobacterium avium subsp. paratuberculosis Infection and Is Dependent Upon Stage of Johne’s Disease. Frontiers in Cellular and Infection Microbiology, 1446.
    • Hernandez, B. G., Vinithakumari, A. A., Sponseller, B., Tangudu, C., & Mooyottu, S. (2020). Prevalence, Colonization, Epidemiology, and Public Health Significance of Clostridioides difficile in Companion Animals. Frontiers in Veterinary Science7, 512551-512551.
    • Lidbury, J. A., Mooyottu, S., & Jergens, A. E. (2020). Triaditis: Truth and Consequences. Veterinary Clinics: Small Animal Practice50(5), 1135-1156.
    • Pellissery, A. J., Vinayamohan, P. G., Yin, H. B., Mooyottu, S., & Venkitanarayanan, K. (2019). In vitro efficacy of sodium selenite in reducing toxin production, spore outgrowth and antibiotic resistance in hypervirulent Clostridium difficile. Journal of medical microbiology68(7), 1118-1128.
    • Mooyottu, S., Flock, A., Upadhyaya, A., Upadhyaya, I., & Venkitanarayanan, K. Protective Effect of Carvacrol against Gut Dysbiosis and Clostridium difficile Associated Disease in a Mouse Model (2017). Frontiers in Microbiology, 8 (625)
    • Mooyottu, S., Flock, G., & Venkitanarayanan, K. (2017). Carvacrol reduces Clostridium difficile sporulation and spore outgrowth in vitro. Journal of medical microbiology66(8), 1229-1234.
    • Narayanan, A., Muyyarikkandy, M. S., Mooyottu, S., Venkitanarayanan, K., & Amalaradjou, M. A. R. (2017). Oral Supplementation of Trans‐Cinnamaldehyde Reduces Uropathogenic Escherichia coli colonization in a Mouse Model. Letters in Applied Microbiology, 64 (3), 192-19.
    • Bhattaram, V., Upadhyay, A., Yin, H. B., Mooyottu, S., & Venkitanarayanan, K. (2017). Effect of Dietary Minerals on Virulence Attributes of Vibrio cholerae. Frontiers in microbiology8, 911.
    • Mooyottu, S., Flock, G., Kollanoor-Johny, A., Upadhyaya, I., Jayarao, B., & Venkitanarayanan, K. (2015). Characterization of a multidrug resistant C. difficile meat isolates International Journal of Food Microbiology, 192, 111-116.
    • Mooyottu, S., Kollanoor-Johny, A., Flock, G., Bouillaut, L., Upadhyay, A., Sonenshein, A. L., & Venkitanarayanan, K. (2014). Carvacrol and trans-cinnamaldehyde reduce Clostridium difficile toxin production and cytotoxicity in vitro International Journal of Molecular Sciences, 15(3), 4415-4430.