Shankumar Mooyottu

DVM, PhD, Diplomate ACVP
DVM, PhD, Diplomate ACVP
2716 Vet Med


    Education & Certifications  

    2018    Diplomate, American College of Veterinary Pathologists

    2017    MS (Pathobiology - Veterinary Anatomic Pathology), University of Connecticut, Storrs, CT

    2016    PhD (Animal Science – Microbiology), University of Connecticut, Storrs, CT

    2010    MVSc (Veterinary Pathology), Indian Veterinary Research Institute, Bareilly, UP, India

    2008    BVSc (DVM), Kerala Agricultural University, Thrissur, Kerala, India

    • Instructor, Autopsy Practicum (VPTH 456)
    • Anatomic Pathology Resident Training (surgical biopsy, autopsy)
    Research Focus & Interests  
    • Development novel non-antibiotic strategies for controlling important enteric diseases such as C. difficile infection in humans and animals with special reference to gut-microbiome and gut-dysbiosis.
    • Identification of gut-friendly small molecules that could potentially be used for preventing gut-dysbiosis and associated enteric diseases.
    • Molecular epidemiology and potential zoonotic or foodborne transmission of C. difficile infection.
    Selected Publications  
    • Mooyottu, S., Flock, A., Upadhyaya, A., Upadhyaya, I., & Venkitanarayanan, K. Protective Effect of Carvacrol against Gut Dysbiosis and Clostridium difficile Associated Disease in a Mouse Model (2017). Frontiers in Microbiology, 8 (625)
    • Mooyottu, S., Flock, G., & Venkitanarayanan, K. (2017). Carvacrol reduces Clostridium difficile sporulation and spore outgrowth in vitro. Journal of medical microbiology66(8), 1229-1234.
    • Mooyottu, S., Flock, G., Kollanoor-Johny, A., Upadhyaya, I., Jayarao, B., & Venkitanarayanan, K. (2015). Characterization of a multidrug resistant C. difficile meat isolates International Journal of Food Microbiology, 192, 111-116.
    • Mooyottu, S., Kollanoor-Johny, A., Flock, G., Bouillaut, L., Upadhyay, A., Sonenshein, A. L., & Venkitanarayanan, K. (2014). Carvacrol and trans-cinnamaldehyde reduce Clostridium difficile toxin production and cytotoxicity in vitro International Journal of Molecular Sciences, 15(3), 4415-4430.
    • Narayanan, A., Muyyarikkandy, M. S., Mooyottu, S., Venkitanarayanan, K., & Amalaradjou, M. A. R. (2017). Oral Supplementation of Trans‐Cinnamaldehyde Reduces Uropathogenic Escherichia coli colonization in a Mouse Model. Letters in Applied Microbiology, 64 (3), 192-19.
    • Bhattaram, V., Upadhyay, A., Yin, H. B., Mooyottu, S., & Venkitanarayanan, K. (2017). Effect of Dietary Minerals on Virulence Attributes of Vibrio cholerae. Frontiers in microbiology8, 911.
    • Upadhyay, A., Mooyottu, S., Yin, H., Nair, M. S., Bhattaram, V., & Venkitanarayanan, K. (2015). Inhibiting Microbial Toxins Using Plant-Derived Compounds and Plant Extracts. Medicines2(3), 186-211.
    • Upadhyay, A., Upadhyaya, I., Mooyottu, S., & Venkitanarayanan, K. (2016). Eugenol in combination with lactic acid bacteria attenuates Listeria monocytogenes virulence in vitro and in invertebrate model, Galleria mellonella. Journal of medical microbiology.
    • Upadhyaya, I., Upadhyay, A., Kollanoor-Johny, A., Mooyottu, S., Baskaran, S. A., Yin, H. B., & Venkitanarayanan, K. (2015). In-feed supplementation of trans-cinnamaldehyde reduces layer-chicken egg-borne transmission of Salmonella enterica serovar Enteritidis. Applied and environmental microbiology81(9), 2985-2994.
    • Johny, A. K., Upadhyay, A., Baskaran, S. A., Upadhyaya, I., Mooyottu, S., Darre, M., Khan, M., Donoghue, A. M., Donoghue, D. J and Venkitanarayanan, K. 2012. Effect of therapeutic supplementation of plant compounds, trans-cinnamaldehyde and eugenol on Salmonella Enteritidis colonization in market-age broiler chickens. 2012. The Journal of Applied Poultry Research.  21(4) 814-822.