Lipoproteins in cats with Chronic Kidney Disease

Area of Study: 
Internal Medicine

Purpose of Study: 

Altered blood lipoproteins, which are proteins responsible for transporting lipids or fat throughout the body (HDL, LDL, etc) are commonly abnormal in people suffering from chronic kidney disease (CKD).  Lipoprotein abnormalities in CKD may contribute to worsening kidney function.

Although CKD is a very common disease in cats, little is known about why it happens and what factors contribute to a more rapid progression of disease in some cats.  While lipoprotein abnormalities appear to be an important part of the pathogenesis of some cases of CKD in humans, whether abnormalities in lipoproteins also occur in cats is unknown. 

The purpose of this study is to determine if cats with chronic kidney disease (CKD) have abnormalities in their blood lipoproteins.

  1.  Cats must have a previous diagnosis of CKD and have no other major health problems (such as IBD, hyperthyroidism, cancer, etc).
  2. Healthy senior cats (age 9 and above) are also being recruited as age-matched controls.
Client Responsibilities: 

This study involves 1 visit, during which the following will be performed:

  • Physical exam
  • Blood collection for CBC, biochemical profile, T4, and lipoprotein analysis
  • Urine collection for urinalysis and urine protein:creatinine ratio

Cats must be fasted for 12 hours prior to blood sample collection

Client Benefits: 

Study will provide the following free services for qualifying cats:

  1.  Comprehensive health profile (CBC, biochemical profile, urinalysis, and T4)
  2. Urine protein:creatinine ratio

Dr. Laura Van Vertloo: 515-294-4900