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Qijing Zhang

Qijing Zhang
Qijing Zhang

BVsc, MS, PhD

Professor and Associate Dean for Research and Graduate Studies
Vet Microbiology & Preventive Medicine
(515) 294-2038
1116 Vet Med
Expertise / Research Area

Food safety; antibiotic resistance; bacterial genetics; pathogen-host interactions; prevention and control of infectious diseases

Teaching

 

VMPM 586: Medical Bacteriology
Objectives: 1) Develop an understanding of pathogenic bacteria that cause infectious diseases in human beings but do not have enough veterinary importance to warrant coverage in VMPM 386; 2) Explore topics currently of high interest in human and veterinary bacteriology; 3) Develop an understanding of and ability to critique current research relevant to the study of pathogenic bacteria; and 4) Design and present an original research proposal
Education

B.V.Sc    Shandong Agricultural University (China)     1983          Vet Medicine
M.S.       National Inst. Veterinary Biologics (China)   1986          Vet Microbiology
Ph.D.     Iowa State University                                   1994          Immunobiology
Postdoc University of Missouri-Columbia                  1994-1997   Molecular Microbiology

Selected Publications

Wu, Z., O. Sahin, F. Wang, and Q. Zhang. 2014. Proteomic identification of immunodominant membrane-related antigens in Campylobacter jejuni associated with sheep abortion. J. Proteomics. 99: 111-122.

Shen, Z., T. Luangtongkum, Z. Qiang, B. Jeon, L. Wang, and Q. Zhang. 2014. Identification of a novel membrane transporter mediating resistance to organic arsenic in Campylobacter jejuni.  Antimicrob Agents Chemother. 58(4):2021-2029.

Wang Y, M. Zhang, F. Deng, Z. Shen, C. Wu, J. Zhang, Zhang Q, and J. Shen. 2014. Emergence of multidrug-resistant Campylobacter with a horizontally acquired ribosomal RNA methylase. Antimicrob. Agents Chemother. 58(9):5405-5412.

Qin, S.S., Y. Wang, Q. Zhang, M. Zhang, F. Deng, Z. Shen, C. Wu, S. Wang, J. Zhang, and J. Shen, 2014. Report of ribosomal RNA methylase gene erm(B) in multidrug resistant Campylobacter coli. J. Antimicrob. Chemother. 69 (4): 964-968.

Wu Z., O. Sahin, Z. Shen, P. Liu, W.G. Miller, and Q. Zhang. 2013. Multi-omics approaches to deciphering a hypervirulent strain of Campylobacter jejuni. Genome Biol Evol. 5(11):2217-2230.

Mu, Y., Z. Shen, B. Jeon, L. Dai, and Q. Zhang. 2013. Synergistic effects of anti-CmeA and anti-CmeB peptide nucleic acids on sensitizing Campylobacter jejuni to antibiotics. Antimicrob. Agents Chemother. 57:4575-4577.

Hao H., Z. Yuan, Z. Shen, J. Han, Q. Sahin, P. Liu, Q. Zhang. 2013. Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. Antimicrob. Agents Chemother. 57(3):1369-78.

Qin, S.S., Y. Wang, Q. Zhang, X. Chen, Z. Shen, F. Deng, C. Wu, and J. Shen. 2012. Identification of a novel genomic Island conferring resistance to multiple aminoglycoside antibiotics in Campylobacter coli. Antimicrob. Agents Chemother. 56: 5332-5339.

Wang, Y., C. Wu, Q. Zhang, J. Qi, H. Liu, Y. Wang, T. He, L. Ma, J. Lai, Z. Shen, Y. Liu and J. Shen. 2012. Identification of New Delhi metallo-β-lactamase 1 in Acinetobacter lwoffii of food animal origin. PloS ONE 7(5):e37152. doi: 10.1371/journal.pone.0037152.

Liu, H., Y. Wang, C. Wu, S. Schwarz, Z. Shen, B. Jeon, S. Ding, Qijing Zhang and J. Shen. 2012. A novel phenicol exporter gene, fexB, found in enterococci of animal origin. J. Antimicrob. Chemother. 67: 322–325.

Han, J., Y. Wang, O. Sahin, Z. Shen, B. Guo, J. Shen, and Q. Zhang. 2012. A fluoroquinolone resistance associated mutation in gyrA affects DNA supercoiling in Campylobacter jejuni. Front. Cell. Infect. Microbiol. 2:21. doi:10.3389/fcimb.2012.00021.

Sahin, O., C. Fitzgerald, S. Stroika, S. Zhao, R. Sippy, P. Kwan, P. Plummer, J. Han, M. Yaeger, and Q. Zhang.  2012. Molecular Evidence for zoonotic transmission of an emergent highly pathogenic Campylobacter jejuni clone in the United States. J. Clin. Microbiol. 50(3):680-7.

Luangtongkum, T., Z. Shen, V. Seng, O. Sahin, B. Jeon, P. Liu, and Q. Zhang. 2012. Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. Antimicrob. Agents Chemother. 56(3):1300-8.

Plummer, P., O. Sahin, E. Burrough, R. Sippy, K. Mou, J. Rabenold, Mike Yaeger, and Qijing Zhang. 2012. The critical role of LuxS in the virulence of Campylobacter jejuni in a guinea pig model of abortion.  Infect. Immun. 80(2):585-93.

Muraoka W.T. and Q. Zhang. 2011. Phenotypic and genotypic evidence for L-fucose utilization by Campylobacter jejuni. J. Bacteriol. 193(5):1065-75.

Guo, B., Y. Wang, F. Shi, Y.W. Barton, P. Plummer, D.L. Reynolds, D. Nettleton, T. Grinnage-Pulley, J. Lin, and Q. Zhang. 2008. CmeR functions as a pleiotropic regulator and is required for optimal colonization of Campylobacter jejuni in vivo. J. Bact. 190:1879-1890.

Han, J., O. Sahin, Y.W. Barton, and Q. Zhang. 2008. Key role of Mfd in the development of fluoroquinolone resistance in Campylobacter. PLoS Pathog. 4(6): e1000083. doi:10.1371/journal.ppat.1000083.

Leadership

VMPM Departmental Officer of Graduate Education

Chair, CVM International Development Committee

Chair, Research Advisory Committee

Associate Dean for Research and Graduate Studies
 
Chair, Division Z (Animal Health), American Society for Microbiology

 

Honors & Awards

Endowed Frank K. Ramsey Chair in Veterinary Medicine, Iowa State University, 2003-2012.

Pfizer Award for Research Excellence, Iowa State University, 2007

 

Memberships

American Society for Microbiology

Conference of Research Workers in Animal Diseases

American Association for the Advancement of Science

American Veterinary Medical Association

American Association of Avian Pathologists