Food safety; antibiotic resistance; bacterial genetics; pathogen-host interactions; prevention and control of infectious diseases
B.V.Sc Shandong Agricultural University (China) 1983 Vet Medicine
M.S. National Inst. Veterinary Biologics (China) 1986 Vet Microbiology
Ph.D. Iowa State University 1994 Immunobiology
Postdoc University of Missouri-Columbia 1994-1997 Molecular Microbiology
Wu, Z., O. Sahin, F. Wang, and Q. Zhang. 2014. Proteomic identification of immunodominant membrane-related antigens in Campylobacter jejuni associated with sheep abortion. J. Proteomics. 99: 111-122.
Shen, Z., T. Luangtongkum, Z. Qiang, B. Jeon, L. Wang, and Q. Zhang. 2014. Identification of a novel membrane transporter mediating resistance to organic arsenic in Campylobacter jejuni. Antimicrob Agents Chemother. 58(4):2021-2029.
Wang Y, M. Zhang, F. Deng, Z. Shen, C. Wu, J. Zhang, Zhang Q, and J. Shen. 2014. Emergence of multidrug-resistant Campylobacter with a horizontally acquired ribosomal RNA methylase. Antimicrob. Agents Chemother. 58(9):5405-5412.
Qin, S.S., Y. Wang, Q. Zhang, M. Zhang, F. Deng, Z. Shen, C. Wu, S. Wang, J. Zhang, and J. Shen, 2014. Report of ribosomal RNA methylase gene erm(B) in multidrug resistant Campylobacter coli. J. Antimicrob. Chemother. 69 (4): 964-968.
Wu Z., O. Sahin, Z. Shen, P. Liu, W.G. Miller, and Q. Zhang. 2013. Multi-omics approaches to deciphering a hypervirulent strain of Campylobacter jejuni. Genome Biol Evol. 5(11):2217-2230.
Mu, Y., Z. Shen, B. Jeon, L. Dai, and Q. Zhang. 2013. Synergistic effects of anti-CmeA and anti-CmeB peptide nucleic acids on sensitizing Campylobacter jejuni to antibiotics. Antimicrob. Agents Chemother. 57:4575-4577.
Hao H., Z. Yuan, Z. Shen, J. Han, Q. Sahin, P. Liu, Q. Zhang. 2013. Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. Antimicrob. Agents Chemother. 57(3):1369-78.
Qin, S.S., Y. Wang, Q. Zhang, X. Chen, Z. Shen, F. Deng, C. Wu, and J. Shen. 2012. Identification of a novel genomic Island conferring resistance to multiple aminoglycoside antibiotics in Campylobacter coli. Antimicrob. Agents Chemother. 56: 5332-5339.
Wang, Y., C. Wu, Q. Zhang, J. Qi, H. Liu, Y. Wang, T. He, L. Ma, J. Lai, Z. Shen, Y. Liu and J. Shen. 2012. Identification of New Delhi metallo-β-lactamase 1 in Acinetobacter lwoffii of food animal origin. PloS ONE 7(5):e37152. doi: 10.1371/journal.pone.0037152.
Liu, H., Y. Wang, C. Wu, S. Schwarz, Z. Shen, B. Jeon, S. Ding, Qijing Zhang and J. Shen. 2012. A novel phenicol exporter gene, fexB, found in enterococci of animal origin. J. Antimicrob. Chemother. 67: 322–325.
Han, J., Y. Wang, O. Sahin, Z. Shen, B. Guo, J. Shen, and Q. Zhang. 2012. A fluoroquinolone resistance associated mutation in gyrA affects DNA supercoiling in Campylobacter jejuni. Front. Cell. Infect. Microbiol. 2:21. doi:10.3389/fcimb.2012.00021.
Sahin, O., C. Fitzgerald, S. Stroika, S. Zhao, R. Sippy, P. Kwan, P. Plummer, J. Han, M. Yaeger, and Q. Zhang. 2012. Molecular Evidence for zoonotic transmission of an emergent highly pathogenic Campylobacter jejuni clone in the United States. J. Clin. Microbiol. 50(3):680-7.
Luangtongkum, T., Z. Shen, V. Seng, O. Sahin, B. Jeon, P. Liu, and Q. Zhang. 2012. Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. Antimicrob. Agents Chemother. 56(3):1300-8.
Plummer, P., O. Sahin, E. Burrough, R. Sippy, K. Mou, J. Rabenold, Mike Yaeger, and Qijing Zhang. 2012. The critical role of LuxS in the virulence of Campylobacter jejuni in a guinea pig model of abortion. Infect. Immun. 80(2):585-93.
Muraoka W.T. and Q. Zhang. 2011. Phenotypic and genotypic evidence for L-fucose utilization by Campylobacter jejuni. J. Bacteriol. 193(5):1065-75.
Guo, B., Y. Wang, F. Shi, Y.W. Barton, P. Plummer, D.L. Reynolds, D. Nettleton, T. Grinnage-Pulley, J. Lin, and Q. Zhang. 2008. CmeR functions as a pleiotropic regulator and is required for optimal colonization of Campylobacter jejuni in vivo. J. Bact. 190:1879-1890.
Han, J., O. Sahin, Y.W. Barton, and Q. Zhang. 2008. Key role of Mfd in the development of fluoroquinolone resistance in Campylobacter. PLoS Pathog. 4(6): e1000083. doi:10.1371/journal.ppat.1000083.
VMPM Departmental Officer of Graduate Education
Chair, CVM International Development Committee
Chair, Research Advisory Committee
Associate Dean for Research and Graduate Studies
Chair, Division Z (Animal Health), American Society for Microbiology
Council Member, CRWAD
Endowed Frank K. Ramsey Chair in Veterinary Medicine, Iowa State University, 2003-2012.
Pfizer Award for Research Excellence, Iowa State University, 2007
Fellow, American Academy of Microbiology, elected 2015
American Society for Microbiology
Conference of Research Workers in Animal Diseases
American Association for the Advancement of Science
American Veterinary Medical Association
American Association of Avian Pathologists