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Bradley Blitvich

Bradley Blitvich
Bradley Blitvich

B.Sc., Ph.D.

Associate Professor
Vet Microbiology & Preventive Medicine
(515) 294-9861
2116 Vet Med
Expertise / Research Area

Dr Blitvich specializes in arthropod-borne viruses (arboviruses) and their mosquito vectors. His primary research focus is to determine the impact of arboviruses, such as West Nile virus and Cache Valley virus, on human and veterinary animal health in the United States and Mexico. Another research focus is to identify the genetic determinants that condition the differential host ranges, transmission dynamics and tropisms of insect-specific and vertebrate-mosquito transmitted flaviviruses.

Teaching

Molecular Viology (VMPM 608)

Graduate Student Seminar Series (VMPM 604)

Education

1991: B.Sc., The University of Western Australia, Perth, Australia

1996: Ph.D., The University of Western Australia, Perth, Australia

1997-1998: Post-doc, Queen Elizabeth II Medical Center, Perth, Australia

1999-2006: Post-doc, Colorado State University, Fort Collins, Colorado, USA

2006-2011: Assistant Professor, Iowa State University, Ames, Iowa, USA

2011-present: Associate Professor, Iowa State University, Ames, Iowa, USA 

Selected Publications

Peer-reviewed publications (last 7 years only): 

 

§ Hobson-Peters J, Lu J, Yam A, Kurucz N, Walsh S, Prow NA, Davis SS, Weir R, Melville L, Hunt N, Webb R, Blitvich BJ, Whelan P and Hall RA. A new insect-specific flavivirus from northern Australia suppresses replication of Kunjin virus and Murray Valley encephalitis virus in co-infected mosquito cells. PLOS One (Accepted).
 
§ Machain-Williams C, Padilla-Paz SE, Weber M, Cetina-Trejo R, Juarez-Ordaz RA, Loroño-Pino MA, Ulloa A, Wang C, Garcia-Rejon J, Blitvich BJ. Antibodies to West Nile virus in wild and farmed crocodiles in southeastern Mexico. Journal of Wildlife Diseases. (Accepted).
 
 
§ Blitvich BJ, Saiyasombat R, Talavera-Aguilar LG, Garcia-Rejon JE, Farfan-Ale JA, Machain-Williams C, Loroño-Pino MA. Orthobunyavirus antibodies in humans, Yucatan Peninsula, Mexico. Emerging Infectious Diseases. 2012. 18(10):1629-32.
 
§ Thompson NN, Auguste AJ, Coombs D, Weaver SC, Blitvich BJ, Carrington CCV, Travassos da Rosa AP, Wang E, Chadee DC, Drebot MA, Tesh RB, Adesiyun AA. Seropositivity of arboviruses in livestock and wildlife in Trinidad. Vector-Borne and Zoonotic Diseases. Vector Borne Zoonotic Dis. 2012. 12(11):969-78.
 
§ Blitvich BJ, Saiyasombat R, Travassos da Rosa APA, Tesh RB, Calisher CH, Garcia-Rejon JE, Farfan-Ale JA, Loroño RE, Bates A, Loroño-Pino MA. Orthobunyaviruses, a common cause of infection of livestock in the Yucatan Peninsula of Mexico. Am J Trop Med Hyg. 2012. 87(6):1132-9.
 
§ Blitvich BJ, Saiyasombat R, Dorman KS, Garcia-Rejon JE, Farfan-Ale JA, Loroño-Pino MA. Sequence and phylogenetic data indicate that an orthobunyavirus recently detected in the Yucatan Peninsula of Mexico is a novel reassortant of Potosi and Cache Valley viruses. Archives of Virology. 2012.
 
§ Blitvich BJ, Staley M, Loroño-Pino MA, Garcia-Rejon JE, Farfan-Ale JA, Dorman KS. Identification of a novel subtype of South River virus (family Bunyaviridae). Archives of Virology. 2012 157(6):1205-9.
 
§ Randall NJ, Blitvich BJ, Blanchong JA. Wildlife rehabilitation centers in surveillance and monitoring for pathogen activity: a case study with West Nile virus. Journal of Wildlife Diseases. 2012. 48(3):646-53.
 
§ Blitvich BJ, Loroño-Pino MA, Garcia-Rejon JE, Farfan-Ale JA, Dorman KS. Nucleotide sequencing and serologic analysis of Cache Valley virus isolates from the Yucatan Peninsula. Virus Genes. 2012. 45(1):176-80.
 
§ Ibarra-Juarez L, Eisen L, Bolling B, Beaty BJ, Blitvich BJ, Sanchez-Casas RM, Ayala-Sulca YO, Fernandez-Salas I. Detection of West Nile virus-specific antibodies in horses and nucleic acid in mosquitoes, from Nuevo Leon State, northern Mexico, 2006-2007. Medical and Veterinary Entomology. 2012. 26(3):351-4.
 
§ Ledermann JP, Lorono-Pino MA, Ellis C, Shaw K, Blitvich BJ, Beaty BJ, Bowen RA, Powers AM. Sequential flavivirus infections of equines: detection of host antibody response and comparison of widely-used diagnostic techniques. Clin Vaccine Immunol. Clin Vaccine Immunol. 2011 18(4):580-7.
 
§ Foy BD, Kobylinski KC, Chilson-Foy JL, Blitvich BJ, Travassos Da Rosa A, Haddow AD, Lanciotti RS, Tesh RB. Probable non-vector-borne transmission of Zika virus in Colorado, USA. Emerg Infect Dis. 2011 17(5):880-2.
 
§ Hobson-Peters J, Arévalo C, Cheah WY, Blitvich BJ, Tan SE, Sandis A, Nazario LA, Hernández JL, Toye P, Hall RA. Detection of antibodies to West Nile virus in horses, Costa Rica, 2004. Vector Borne Zoonotic Dis. 2011 11(8):1081-4.
 
§ Saiyasombat R, Bolling BG, Brault AC, Bartholomay LC, Blitvich BJ. Evidence of Efficient Transovarial Transmission of Culex flavivirus by Culex pipiens (Diptera: Culicidae). J Med Entomol. 2011 48(5):1031-8.
 
§ Farfan-Ale JA, Loroño-Pino MA, Garcia-Rejon JE, Soto V, Lin M, Staley M, Dorman KS, Bartholomay LC, Hovav E, Blitvich BJ. Detection of flaviviruses and orthobunyaviruses in mosquitoes in the Yucatan Peninsula of Mexico in 2008. Vector Borne Zoonotic Dis. 2010. 10(8):777-83.
 
§ Saiyasombat R, Dorman KS, Bartholomay LC, Garcia-Rejon JE, Loroño-Pino MA, Farfan-Ale JA, Blitvich BJ. Isolation and sequence analysis of Culex flavivirus from Culex interrogator and Culex quinquefasciatus in the Yucatan Peninsula of Mexico. Arch Virol. 2010. 155(6):983-6.
 
§ Root JJ, Bentler KT, Sullivan HJ, Blitvich BJ, McLean RG, Franklin AB. A longitudinal investigation of antibody responses in raccoons naturally exposed to multiple subtypes of influenza A virus. Vector Borne Zoonotic Dis. 2010. 10(8):821-3.
 
§ Staley M, Dorman KS, Bartholomay LC, Fernández-Salas I Farfan-Alé, JA, Loroño-Pino MA, Garcia-Rejon JE, Ibarra-Juarez L, Blitvich BJ. Universal primers for the amplification and sequence analysis of actin-1 from diverse mosquito species. J Am Mosq Control Assoc. 2010. 26(2):214-8.
 
§ Seiler BM, Yoon KJ, Andreasen CB, Block SM, Marsden S, Blitvich BJ. Seroprevalence for influenza A virus (H1 and H3) in domestic animals in Iowa. Vet Record. 2010. 167(18):705-7.
 
§ Garcia-Rejon JE. Blitvich BJ, Farfan-Ale JA, Loroño-Pino MA, Chi Chim WA, Flores-Flores LF,Rosado-Paredes E,Baak-Baak C, Perez-Mutul J, Suarez-Solis V, Fernandez-Salas I, Beaty BJ. Host-feeding preference of Culex quinquefasciatus in Yucatan State, Mexico. J. Insect Sci. 2010 Mar;10:32.
 
§ Blitvich BJ, Ibarra-Juarez LA, Cortes-Guzman AJ, Root JJ,Franklin AB, Sullivan HJ, Fernandez-Salas I. Seroprevalence for equine influenza virus in northeast and southern Mexico. Vet. Record. 2010. 166(18):565-6.
 
§ Rios-Ibarra C, Blitvich BJ, Farfan-Ale J, Ramos-Jimenez J, Muro-Escobedo S, Ortiz-López R, Torres-López E, Rivas-Estilla AM. Fatal human case of West Nile virus disease, Mexico, 2009. Emerg Infect Dis. 2010 16(4):741-3.
 
§ Firth AE, Blitvich BJ, Wills NM, Miller CL, Atkins JF. Evidence for ribosomal frameshifting and a novel overlapping gene in the genomes of insect-specific flaviviruses. Virology. 2010. 399(1):153-66.  
 
§ Tiawsirisup S, Blitvich BJ, Tucker BJ, Halbur HG, Bartholomay LC, Rowley WA, Platt KB. Susceptibility of fox squirrels (Sciurus niger) to West Nile virus by oral exposure. Vector Borne Zoonotic Dis. 2010. 10(2):207-9.
 
§ Loroño-Pino MA, Farfan-Ale JA, Garcia-Rejon JE, Lin M, Rosado-Paredes E, Puerto FI, Bates A, Root JJ,Franklin AB, Sullivan HJ, Blitvich BJ. Antibodies to Influenza and West Nile viruses in horses in Mexico. Vet. Record. 2010. 166(1):22-3.
 
§ Melian EB, Hinzman E, Nagasaki T, Firth AE, Wills NM, Nouwens AS, Blitvich BJ, Leung J, Funk A, Atkins JF, Hall R, Khromykh AA. NS1' of Flaviviruses in the Japanese Encephalitis Virus Serogroup Is a Product of Ribosomal Frameshifting and Plays a Role in Viral Neuroinvasiveness. J Virol. 2010. 84(3):1641-7.
 
§ Garza-Rodríguez ML, Rodríguez-Rodriguez DR, Blitvich BJ, Reyes MA, Fernández-Salas I, Jimenez JR, Farfán-Ale JA, Tamez RC, Martinez-Longoria C, Tavitas-Aguilar MI, Rivas-Estilla AM. Serologic surveillance for West Nile virus and other flaviviruses in febrile patients, encephalitic patients and asymptomatic blood donors in northern Mexico. Vector Borne Zoonotic Dis. Vector Borne Zoonotic Dis. 2010. 10(2):151-7.
 
§ Blitvich BJ, Ibarra-Juarez L, Tucker BJ, Rowley WA, Platt KB. Antibodies to West Nile virus in raccoons and other wild peridomestic mammals in Iowa. J. Wildlife Dis. 2009. 45:1163-8.
 
§ Dunphy BM, Tucker BJ, Petersen M, Blitvich BJ, Bartholomay LC.The arrival and establishment of Aedes japonicus japonicus (Diptera: Culicidae) in Iowa, USA. J. Med. Ent. 2009. 46(6):1282-9.
 
§ Soto V, Dorman KS, Farfan-Ale JA, Loroño-Pino MA, Garcia-Rejon JE, Blitvich BJ. Complete nucleotide sequence of the small and medium RNA genome segments of Kairi virus (family Bunyaviridae). Arch. Virol. 2009. 154(9): 1555-8.
 
§ Blitvich BJ, Lin M, Dorman KS, Soto V, Hovav E, Tucker BJ, Staley M, Platt KB, Bartholomay LC. Genomic sequence and phylogenetic analysis of Culex flavivirus, an insect-specific flavivirus, isolated from Culex pipiens in Iowa. J. Med Ent. 2009. 46(4): 934-41.
 
§ Sullivan HJ, Blitvich BJ, VanDalen K, Bentler KT, Franklin AB, Root JJ. Evaluation of an epitope-blocking enzyme-linked immunosorbent assay for the detection of antibodies to Influenza A virus in domestic and wild avian and mammalian species. J. Virol Methods. 2009. 161:141-6.
 
§ Farfan-Ale JA, Loroño-Pino MA, Garcia-Rejon JE, Hovav E, Powers AM, Lin M, Dorman KS, Platt KB, Bartholomay LC, Soto V, Beaty BJ, Lanciotti RS, Blitvich BJ. Detection of RNA from a novel West Nile-like virus and high prevalence of an insect-specific flavivirus in mosquitoes in the Yucatan Peninsula of Mexico. Am J Trop Med Hyg. 2009. 80(1):85-95.
 
§ Loroño-Pino MA, Farfan-Ale JA, Blitvich BJ, Beebe JL, Jarman RG, Beaty BJ. Evaluation of an Epitope-Blocking Enzyme-Linked Immunosorbent Assay for the Diagnosis of West Nile Virus Infections in Humans. 2009. 16(5):749-55.
 
§ Blitvich BJ. Transmission dynamics and changing epidemiology of West Nile virus. Anim Health Res Rev. 2008 9(1):71-86.
 
§ Platt KB, Tucker BJ, Halbur PG, Blitvich BJ, Fabiosa FG, Mullin K, Parikh GR, Kitikoon P, Bartholomay LC, Rowley WA. Fox squirrels (Sciurus niger) develop West Nile virus viremias sufficient for infecting select mosquito species. Vector Borne Zoonotic Dis. 2008 8(2):225-33.
 
§ Reese SM, Blitvich BJ, Blair CD, Geske D, Beaty BJ, Black WC. Potential for La Crosse virus segment reassortment in nature. Virol. J. 2008 5(1):164.
 
§ Beck ET, Blair CD, Black WC, Beaty BJ, Blitvich BJ. Alternative splicing generates multiple transcripts of the Inhibitor of Apoptosis Protein 1 in Aedes and Culex sp. mosquitoes. Insect Mol Biol. 2007 37(11):1222-33.
 
§ Platt KB, Tucker BJ, Halbur PG, Tiawsirisup S, Blitvich BJ, Fabiosa FG, Bartholomay LC, Rowley WA. West Nile virus viremia in eastern chipmunks (Tamias striatus) sufficient for infecting different mosquitoes. Emerg Infect Dis. 2007. 13(6):831-7.
 
§ Sondgeroth K, Blitvich BJ, Blair CD, Terwee J, Junge R, Sauther M, VandeWoude S. Assessing Flavivirus, Lentivirus, and Herpesvirus Exposure in wild Lemur catta in southwestern Madagascar. J. Wildlife Dis. 2007. 43(1):40-7.
 
§ Li Q, Li H, Blitvich BJ, Zhang J. The Aedes albopictus inhibitor of Apoptosis 1 gene protects vertebrate cells from bluetongue virus-induced apoptosis. Insect Mol Biol. 2007. 16(1):93-105.
Memberships

1998 – present: American Society for Virology (Life Member)

2001 – present: American Society for Tropical Medicine and Hygiene (Member)