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Publications

Subject Area

Mycoplasma Genetics and Genomics
Mycoplasma hyopneumoniae Adherence and Surface Activities
Microarrays
E. coli O157:H7 Related Publications
ESAT-6 Related Publications
Other

 

 

Mycoplasma Genetics and Genomics

  • Mahairas, G. G., and F. C. Minion. 1989. Random insertion of the gentamicin resistance transposon Tn4001 in Mycoplasma pulmonis. Plasmid. 21:43-47.
  • Mahairas, G. G., and F. C. Minion. 1989. Transformation of Mycoplasma pulmonis: Demonstration of homologous recombination, introduction of cloned genes and the preliminary description of an integrating shuttle system. J. Bacteriol. 171:1775-1780.
  • Mahairas, G. G., C. Jian, and F. C. Minion. 1989. Exchange of transposon inserts and integrative plasmids in Mycoplasma pulmonis. J. Bacteriol. 172:2267-2272.
  • Mahairas, G. G., Cao J., and F. C. Minion. 1990. Development of a cloning system in Mycoplasma pulmonis. Gene 93:61-65.
  • Knudtson, K. L., and F. C. Minion. 1993. Construction of Tn4001 lac derivatives to be used as promoter probe vectors in mycoplasmas. Gene 137:217-222.
  • Smiley, Brenda K., and F. C. Minion. 1993. Enhanced readthrough of opal (UGA) codons in mycoplasma gene sequences and production of Mycoplasma pneumoniae P1 epitopes in Escherichia coli. Gene 134:33-40.
  • Artiushin, S., Stipkovits, L., and F. C. Minion. 1993. Development of polymerase chain reaction primers to detect Mycoplasma hyopneumoniae. Mol. Cell. Probes 7:101-105.
  • Tigges, E., and F. C. Minion. 1994. Physical map of the genome of Acholeplasma oculi ISM1499 and construction of a Tn4001 derivative for macrorestriction chromosomal mapping. J. Bacteriol. 176:1180-1183.
  • Kapke, P. A., K. L. Knudtson, and F. C. Minion. 1994. Transformation of Mollicutes with single-stranded Tn4001-containing DNA. Plasmid 32:85-88.
  • Knudtson, K. L., and F. C. Minion. 1994. Use of lac gene fusions in the analysis of Acholeplasma upstream gene regulatory regions. J. Bacteriol. 176: 2763-2766.
  • Tigges, E., and F. C. Minion. 1994. Physical map of Mycoplasma gallisepticum. J. Bacteriol. 176:4157-4159.
  • Jian, C., P. A. Kapke, and F. C. Minion. 1994. Transformation of Mycoplasma gallisepticum with Tn916, Tn4001 and integrative plasmid vectors. J. Bacteriol. 176:4459-4462.
  • Artiushin, S., M. Duvall, and F. C. Minion. 1995. Phylogenetic analysis of mycoplasma strain ISM1499 and its assignment to the Acholeplasma oculi strain cluster. Int. J. Syst. Bacteriol. 45:104-109.
  • Minion , F. C., C. VanDyk, and B. K. Smiley. 1995. Use of an enhanced Escherichia coli opal suppressor strain to screen a Mycoplasma hyopneumoniae library. FEMS Microbiol. Lett. 131:81-85.
  • Artiushin, S., and F. C. Minion. 1996. Arbitrarily-primed PCR analysis of Mycoplasma hyopneumoniae field isolates demonstrates genetic heterogeneity. Int. J. Syst. Bacteriol.46:324-328.
  • Pour-El, I., C. Adams, and F. C. Minion. 2002. Construction of mini-Tn4001tet and its use in Mycoplasma gallisepticum. Plasmid 47:129-137.
  • Minion, F. C., E. L. Lefkowitz, M. L. Madsen, B J. Cleary, S. M. Swartzell, and G. G. Mahairas. 2004. The genome sequence of Mycoplasma hyopneumoniae strain 232, the agent of swine mycoplasmosis. J. Bacteriol. 186:7123-7133.
  • Chang, L.-J., W.-H. Chen, F. C. Minion and D. Shiuan. 2008. Mycoplasmas regulate the expression of heat shock protein genes through CIRCE-HrcA interactions. Biochem. Biophys. Res. Commun. 367:213-218.
  • Gardner, S. W., and F. C. Minion. 2010. Detection and quantification of intergenic transcription in Mycoplasma hyopneumoniae. Microbiol. 156:2305-2315.

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Mycoplasma Adherence and Surface Activities

  • Minion, F. C., and J. D. Goguen. 1985. A trypsin-sensitive, bovine serum albumin-dependent hemolysis activity in Mycoplasma pulmonis. Infect. Immun. 49:440-442.
  • Minion, F. C., and J. D. Goguen. 1986. Identification and preliminary characterization of a membrane-bound endonuclease in Mycoplasma pulmonis. Infect. Immun. 51:352-354.
  • Minion, F. C., Jarvill-Taylor, K. J., Billings, D. E., and E. Tigges. 1993. Membrane-associated nuclease activities in mycoplasmas. J. Bacteriol. 175:7842-7847.
  • Minion, F. C., and K. Jarvill-Taylor. 1994. Membrane-associated hemolysin activities in Mycoplasma. FEMS Microbiol. Lett. 116:101-106.
  • Minion , F. C., C. VanDyk, and B. K. Smiley. 1995. Use of an enhanced Escherichia coli opal suppressor strain to screen a Mycoplasma hyopneumoniae library. FEMS Microbiol. Lett. 131:81-85.
  • Jarvill-Taylor, K., and F. C. Minion. 1995. The effect of thiol-active compounds and sterols on the membrane-associated hemolysin of Mycoplasma pulmonis. FEMS Microbiol. Lett. 128:213-218.
  • Hsu, T., S. Artiushin, and F. C. Minion. 1997. Cloning and functional analysis of the P97 swine cilia adhesin gene of Mycoplasma hyopneumoniae. J. Bacteriol. 179:1317-1323.
  • Hsu, T., and F. C. Minion. 1998. Molecular analysis of the ciliary adhesin P97 operon of Mycoplasma hyoneumoniae. Gene 214:13-23.
  • Hsu, T., and F. C. Minion. 1998. Identification and functional analysis of the cilium binding epitope of Mycoplasma hyopneumoniae P97 adhesin. Infect. Immun. 66:4762-4766.
  • Jarvill-Taylor, K. J., C. VanDyk, and F. C. Minion. 1999. Cloning of mnuA, a membrane-associated nuclease gene of Mycoplasma pulmonis, and analysis of its expression in Escherichia coli . J. Bacteriol. 181:1853-1860.
  • Minion, F. C., C. Adams, T. Hsu. 2000. R1 region of P97 mediates adherence of Mycoplasma hyopneumoniae to swine cilia. Infect. Immun. 68:3056-3060.
  • Pharr, G. T., S. L. Branton, L. A. Hanson, F. C. Minion, M. B. Hughlett, and X. Wan. 2002. Characterization of pMGA genes from the F-strain (vaccine strain) of Mycoplasma gallisepticum. Int. J. Poultry Sci. 1 (4): 63-73.
  • Kurth, K.T., S.A. Menon, T. Hsu, D. Spencer and F. C. Minion. 2002. Cloning of a species-specific P75 protein gene from Mycoplasma gallisepticum. Avian Dis. 46:816-825.
  • Matic, J.N., J.L. Wilton, R.J. Towers, A.L. Scarman, F.C. Minion, M.J. Walker and S.P. Djordjevic. 2003. The pyruvate dehydrogenase complex of Mycoplasma hyopneumoniae contains a novel lipoyl domain arrangement. Gene 319:99-106.
  • Djordjevic, S. P., S. J. Cordwell, M. A. Djordjevic, J. Wilton, and F. C. Minion. 2004. Proteolytic processing of the Mycoplasma hyopneumoniae cilium adhesin. Infect. Immun. 72:2791-2802.
  • Adams, C., J. Pitzer, and F. C. Minion. 2005. In vivo expression analysis of the P97 and P102 paralog families of Mycoplasma hyopneumoniae. Infect. Immun. 73:7784-7787.
  • Jenkins, C., J. L. Wilton, F. C. Minion, L. Falconer, M. J. Walker, and S. P. Djordjevic. 2005. Two domains within the Mycoplasma hyopneumoniae cilium adhesin bind heparin. Infect. Immun. 74:481-487.
  • Burnett, T.A., K. Dinkla, M. Rohde, G.S. Chhatwal, M. Srivastava, S.J. Cordwell, S. Geary, F. C. Minion,. M. J. Walker, S. P. Djordjevic. 2006. P159 is a proteolytically processed, surface adhesin of Mycoplasma hyopneumoniae: defined domains of P159 bind heparin and promote adherence to eukaryotic cells. Mol. Microbiol. 60:669-686.
  • Wilton, J., C. Jenkins, S. Cordell, L. Falconer, F. Minion, D. Oneal, M. Djordjevic, A. Connolly, I. Barchia, M. Walker, and S. P. Djordjevic. 2009. Mhp493 (P216) is a proteolytically processed, cilium and heparin binding protein of Mycoplasma hyopneumoniae. Mol. Micro. 71: 566-582.
  • Deutscher, A. T., C. Jenkins, F. C. Minion, M. Padula, L. M. Seymour, N. E. Dixon, M. J. Walker, and S. P. Djordjevic. 2010. Repeat regions R1 and R2 in the P97 paralog Mhp271 of Mycoplasma hyopneumoniae bind heparin, fibronectin, and porcine cilia. Mol. Microbiol. 78:444-458.
  • Seymour, L. M., A. T. Deutscher, C. Jenkins, T. A. Kuit, L. Falconer, F. C. Minion, B. Crossett, M. Apdula, N. E. Dixon, S. P. Djordjevic, and M. J. Walker. 2010. A processed multidomain Mycoplasma hyopneumoniae adhesin binds fibronectin, plasminogen and swine respiratory cilia. J. Biol. Chem. 285:33971-33978.
  • Seymour, L. M., L. Falconer, A. T. Deutscher, F. C. Minion, M. P. Padula, N. E. Dixon, S. P. Djordjevic, and M. J. Walker. 2011. Mhp107 is a member of the multifunctional adhesin family of Mycoplasma hyopneumoniae. J. Biol. Chem. 286:10097-10104.
  • Bogema, D. R, N. E. Scott, M. Padula, J. L. Tacchi, C. Jenkins, S. J. Cordwell, F. C. Minion, M. J. Walker, S. P. Djordjevic. 2012. The peptide sequence TTKF | QE defines the site of proteolytic cleavage in Mhp683 (P135), a novel glycosaminoglycan and cilium binding adhesin of Mycoplasma hyopneumoniae. J. Biol. Chem. 286:41217-41229.

  • Deutscher, A. T., J. L. Tacchi, F. C. Minion, M. P. Padual, B. Crossett, D. R. Bogema, C. Jenkins, M. J. Walker, S. P. Djordjevic. 2012. Mycoplasma hyopneumoniae surface proteins Mhp385 and Mhp384 bind host cilia and glycosaminoglycans and are endoproteolytically processed by proteases that recognize different cleavage motifs. J. Proteome Res. 11:1924-1936.
  • Bogema, D. R., A. T. Deutscher, L. M. Seymour, B. B. A. Raymond, J. L. Tacchi, M. P. Padula, N. E. Dixon, F. C. Minion, C. Jenkins, M. J. Walker, and S. P. Djordjevic. 2012. Characterization of cleavage events in the multifunctional cilium adhesin Mhp684 (P146) reveals a novel mechanism by which Mycoplasma hyopneumoniae regulates surface topography. mBio 3:e00282-11.

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Mycoplasma Microarrays

  • Madsen, M. L., D. Nettleton, E. L. Thacker, R. Edwards, and F. C. Minion. 2006. Transcriptional profiling of Mycoplasma hyopneumoniae during heat shock using microarrays. Infect. Immun. 74:167-174.
  • Madsen, M. L., D. Nettleton, E. L. Thacker, and F. C. Minion. 2006. Transcriptional profiling of Mycoplasma hyopneumoniae during iron depletion using microarrays. Microbiology 152:937-944.
  • Schafer, E. R., M. J. Oneal, M. L. Madsen, and F. C. Minion. 2007. Global transcriptional analysis of Mycoplasma hyopneumoniae following exposure to hydrogen peroxide. Microbiology (In press).
  • Madsen, M. L., M. J. Oneal, S. W. Gardner, E. L. Strait, D. Nettleton, E. L. Thacker, and F. C. Minion. 2007. Array-based genomic comparative hybridization of field strains of Mycoplasma hyopneumoniae. J. Bacteriol. 189:7977-7982.
  • Madsen, M. L., S. Puttamreddy, E. L. Thacker, M. D. Carruthers, F. C. Minion. 2008. Transcriptome changes in Mycoplasma hyopneumoniae during infection. Infect. Immun. 76:658-663.
  • Puttamreddy, S., M. D. Carruthers, M;. L. Madsen, and F. C. Minion. 2008. Transcriptome analysis of organisms with food safety relevance. Foodborne Pathog. Dis. 5:517-529.
  • Strait, E. L., M. L. Madsen, F. C. Minion, J. Christopher-Hennings, M. Dammen, K. R. Jones, E. L. Thacker. 2008. Real-time PCR assays to address genetic diversity in Mycoplasma hyopneumoniae. J. Clin. Microbiol. 46:2491-2498.
  • Oneal, M. J., E. R. Schafer, M. L. Madsen and F. C. Minion. 2008. Global transcriptional analysis of Mycoplasma hyopneumoniae following exposure to norepinephrine. Microbiol. 154:2581-2588.
  • Kong, C. S., J. Yu, F. C. Minion, and K. Rajan. 2011. Identification of biologically significant genes from combinatorial microarray data. ACS Combi. Sci. 13:562-571.

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E. coli O157:H7-Related Publications

  • Carruthers, M. D., and F. C. Minion. Transcriptome analysis of Escherichia coli O157:H7 during heat shock. FEMS Microbiol. Lett. 295:96-102.
  • Puttamreddy, S., N. S. Cornick, and F. C. Minion. 2010. Genome-wide transposon mutagenesis of Escherichia coli O157:H7 EDL933 identified pO157 genes involved in biofilm formation. Infect. Immun. 78:2377-2384.
  • Carruthers, M. D., B. H. Bellaire, and F. C. Minion. 2010. Exploring the response of Escherichia coli O157:H7 EDL933 within Acanthamoeba castellanii by genome-wide transciptional profiling. FEMS Microbiol. Lett. 312:15-23.
  • Puttamreddy, S., and F. C. Minion. 2011 Linkage between cellular adherence and biofilm formation in Escherichia coli O157:H7 EDL933. FEMS Microbiol. Lett. 315:46-53.

ESAT-6-Related Publications

  • Minion, F.C., S.A. Menon, G.G. Mahairas, and M.J. Wannemuehler. 2003. Enhanced Murine Antigen-Specific IFN-gamma  Responses Using Mycobacterial ESAT-6 Sequences in DNA Vaccines. Infect. Immun. 71:2239-2242.
  • Menon, S. A. M., J. Wannemuehler, G. G. Mahairas, and F. C. Minion. 2002. Mycobacterial ESAT-6 protein enhances mouse interferon-gamma responses to Mycoplasma hyopneumoniae P71 protein. J. Interf. Cytok. Res. 22:807-813.
  • W.R. Waters, B.J. Nonnecke, M.V. Palmer, S. Robbe-Austermann, J.P. Bannantine, J.R. Stabel, D.L. Whipple, J.B. Payeur, D.M. Estes, J.E. Pitzer, and F.C. Minion. 2003 . Use of recombinant ESAT-6:CFP-10 fusion protein for differentiation of infections of cattle by Mycobacterium bovis and by M. avium subsp. avium and M. avium subsp. paratuberculosis. Clin. Diagn. Lab. Immunol. 11:729-735.
  • Maue, A. C., R. W. Waters, M. V. Palmer, D. L. Whipple, F. C. Minion, W. C. Brown, and D. M. Estes. 2004. CD80 and CD86, but not CD154, augment DNA vaccine-induced protection in experimental bovine tuberculosis. Vaccine 23:769-779.
  • Maue, A. C., W. C. Davis, M. V. Palmer, F. C. Minion, D. M. Estes, and W. R. Waters. 2005. Analysis of immune responses from Mycobacterium bovis-infected cattle directed toward a recombinant ESAT-6:CFP10 fusion protein. Infect. Immun. 73:6659-6667.
  • Waters, W. R., M. V. Palmer, R E. Slaughter, S. L. Jones, J. E. Pitzer, F. C. Minion. 2006. Diagnostic implications of antigen-induced gamma interferon production by blood leukocytes from Mycobacterium bovis-infected reindeer (Rangifer tarandus). Clin. Diagn. Lab. Invest. 13:37-44.
  • Waters, W. R., Palmer, M. V., Thacker, T. C., Minion, F. C., and Davis, W. C. 2006. Antigen-specific proliferation and activation of peripheral blood mononuclear cells from Mycobacterium bovis-infected reindeer. Vet. Immunol. Immunopathol. 111:263-277.
  • Waters, W. R., M. V. Palmer, T. C. Thacker, J. B. Payeur, N. B. Harris, F. C. Minion, R. Greenwald, J. Esfandiari, P. Andersen, J. McNair, J. M. Pollock, and K. P. Lyashchenko. 2006. Immune responses to defined antigens of Mycobacterium bovis in cattle experimentally infected with Mycobacterium kansasii: potential interference with diagnostic tests for bovine tuberculosis. Clin. Vacc. Immunol. 13:611-619.
  • Maue, A. C., Waters, W. R., Palmer, M. V., Nonnecke, B. J., Minion, F. C., Brown, W. C., Norimine, J., Foote, M. R., Scherer, C. C. and Estes, M. D. 2007. An ESAT- 6:CFP10 DNA vaccine administered in conjunction with Mycobacterium bovis BCG confers protection to cattle challenged with virulent Mycobacterium bovis. Vaccine 25:4735-4746.

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Other

  • Hsu, T., D. L. Hutto, F. C. Minion, R. L. Zuerner, and M. J. Wannemuehler. 2001. Cloning of a beta-hemolysin gene of Brachyspira (Serpulina) hyodysenteriae and its expression in Escherichia coli Infect. Immun. 69:706-711.
  • Kurth, K. T., T. Hsu, E. L. Thacker, B. Thacker, F. C. Minion. 2002. Use of a Mycoplasma hyopneumoniae nested PCR test to determine the optimal sampling sites in swine. J. Vet. Diagn. Invest. 14:463-469.
  • Park, S.-C., S. Yibchok-Anun, H. Cheng, T. F. Young, E. L. Thacker, F. C. Minion, R. F. Ross, and W. H. Hsu. 2002. Mycoplasma hyopneumoniae increases intracellular calcium release in porcine ciliated tracheal cells. Infect. Immun. 70:2502-2506.
  • Minion, F. C. 2002. Molecular Pathogenesis of animal mycoplasma respiratory pathogens. Front. Biosci. 7: d1410-1422. URL: http://www.bioscience.org/ 2002/v7/d/minion/fulltext.htm.
  • Pharr, G. T., S. L. Branton, L. A. Hanson, F. C. Minion, M. B. Hughlett, and X. Wan. 2002. Characterization of pMGA genes from the F-strain (vaccine strain) of Mycoplasma gallisepticum. Int. J. Poultry Sci. 1 (4): 63-73.
  • Zuerner, R. L., T. B. Stanton, F. C. Minion, C. Li, N. W. Charon, D. J. Trott, and D. J. Hampson. 2004. Genetic Variation in Brachyspira: chromosomal rearrangements and sequence drift distinguish B. pilosicoli from B. hyodysenteriae. Anaerobe 10: 229-237.
  • Stakenborg, T., Vicca, J., Butaye, P., Maes, D., Minion, C., Peeters, J., de Kruif, A, Haesebrouck, F. 2005. Characterization of in vivo acquired resistance of Mycoplasma hyopneumoniae to macrolides and lincosamides. Microbial Drug Resistance 3:290-294.
  • Vicca, J., D. Maes, T. Stakenborg, P. Butaya, F. Minion, J. Peeters, A. De Kruif, A. Decostere, and F. Haesebrouck. 2007. Resistance mechanism against fluoroquinolones in Mycoplasma hyopneumoniae field isolates. Microb. Drug Resist. 13:166-170.
  • Strait, E. L., M. L. Madsen, F. C. Minion, J. Christopher-Hennings, M. Dammen, K. R. Jones, E. L. Thacker. 2008. Real-time PCR assays to address genetic diversity in Mycoplasma hyopneumoniae. J. Clin. Microbiol. 46:2491-2498.
  • Thacker, E. L., and F. C. Minion. 2011. Mycoplasmosis. In Diseases of Swine, 10th Edition. Wiley-Blackwell. New York.

  • Madsen, M. L., and F. C. Minion. 2012. Stress response in mycoplasmas. In Stress Response in Microbiology, Horizon Scientific Press, Norwich, U.K. (http://www.horizonpress.com/stressresponse)

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Last Updated June 29, 2012