Dipak Kumar Sahoo

MSc, MPhil, PhD
Dipak Kumar Sahoo

Research Scientist III
Veterinary Clinical Sciences
dsahoo@iastate.edu
515-294-7311
1469 Patterson 1800 Chris
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General

I am a Research Scientist in Veterinary Clinical Sciences, and my current research focuses on developing molecular markers and understanding the molecular mechanisms linked to inflammatory bowel diseases, cancer, and sepsis, as well as the impact of antioxidants/oxidative stress in various pathophysiological conditions. I have an extensive research background of over 20 years with doctoral and postdoctoral training in animal biology/zoology, specific training and expertise in working on various disease models, cancer biology, molecular biology, biochemistry, genetics and ex vivo organoid studies (Google Scholar citations: 5328, h-index: 37; i10-index: 92). As of May/June 2025 (Web of Science), my 3 highly cited publications, in which I am the leading author and/or corresponding author, placed 2 in the top 1% of the academic field of Microbiology and Biology & Biochemistry and 1 in the top 0.1% of the academic field of Clinical Medicine. I have reviewed 224 manuscripts for 72 different peer-reviewed international journals from various publishers, including Nature, Elsevier, Springer, Wiley-Blackwell, Hindawi, Frontiers, MDPI, PLoS, and Karger. I received "Sentinels of Science-September 2016" for serving as a "Top peer reviewer" in the fields of Biochemistry, Genetics, and Molecular Biology, in recognition of my contributions as a reviewer. I also served as a Guest Associate Editor for research topics in Frontiers in Endocrinology (Cellular Endocrinology & Translational and Clinical Endocrinology) and Frontiers in Genetics (Human and Medical Genomics). 

Education & Certifications

Postdoctoral Training                                                                                                       2009-2019

Iowa State University, Ames, IA, USA & University of Kentucky, Lexington, KY, USA

Ph.D. in Zoology                                                                                                                 2007

Department of Zoology, Utkal University, INDIA

Thesis title: “Modulation of rat testicular antioxidant defense system by experimentally induced hypo-and hyperthyroidism”; http://hdl.handle.net/10603/190995

M.Phil. in Zoology                                                                                                                2002

Department of Zoology, Utkal University, INDIA

M.Sc. in Zoology (Specialization in Biochemistry)                                                                2001

Department of Zoology, Utkal University, INDIA                           

B.Sc. (Honors with Distinction)                                                                                              1998

Utkal University, Bhubaneswar, Odisha, INDIA 

Honors & Awards

Memberships

  • American Gastroenterological Association (AGA) (2023-today)
  • American Association for Cancer Research (AACR) (2022)
  • American Society of Plant Biologists (2011-2012, 2016, 2018)
  • Society for In Vitro Biology (2013)
  • Indian Society for Comparative Endocrinology (2005-2007)

Selected Publications

Research Publications

Google Scholar Citations (Citations: 5407, h-index: 37, i10-index: 93)

https://scholar.google.com/citations?user=c1Uz3cYAAAAJ&hl=en&inst=10763123895732025241

Selected Publications:

  1. Ghazvini, S., Kandavelkumar, V., Nandu, R., Popp, A., Cutshaw, G., Sahoo, D.K., Jergens, A.E., Wannemeuhler, M. and Bardhan, R., 2026. Understanding Colitis Progression and Treatment Response in Murine and Canine Models with Raman Metabolic Profiling and Proteomics. Analytical Chemistry.
  2. Sahoo, D.K., Wong, D., et al., 2025. Role of Endoplasmic Reticulum Stress-Associated Genes in Septic Neonatal Foals. Antioxidants 2025, Vol. 14, Page 1024 14, 1024. https://doi.org/10.3390/ANTIOX14081024. (Sahoo DK as corresponding author)
  3. Sahoo, D. K., Stewart, T., et al., 2025. Restorative Effects of Synbiotics on Colonic Ultrastructure and Oxidative Stress in Dogs with Chronic Enteropathy. Antioxidants, 14(6), 727. https://doi.org/10.3390/antiox14060727. (Sahoo DK as corresponding author)
  4. Sahoo, D.K., Chainy, G.B.N. and Jergens, A.E., 2025. Editorial: Gastrointestinal (GI) disorders and antioxidant therapeutics. Frontiers in Endocrinology, 16, p.1588417. (Sahoo DK as corresponding author)
  5. Sahoo, D.K., Heilmann, R.M. and Patel, A., 2025. Editorial: Understanding molecular mechanisms to facilitate the development of biomarkers for therapeutic intervention in gastrointestinal diseases and sepsis. Frontiers in Genetics, 16, p.1581299. (Sahoo DK as corresponding author)
  6. Mason, B., Sahoo, D.K., lennarella-Servantez, C.A. et al., 2025. Effects of a western diet on colonic dysbiosis, bile acid dysmetabolism and intestinal inflammation in clinically healthy dogs. J Vet Intern Med. 2025, 39:e70035. https://doi.org/10.1111/jvim.70035. (Sahoo DK as corresponding author)
  7. Wong, D., Sahoo, D.K., Faivre, C., Kopper, J., Dersh, K., Beachler, T., Esser, M., 2025. Oxidative stress in critically ill neonatal foals. J Vet Intern Med. 2025;39:e17297. 
  8. Sahoo, D.K., Samanta, L., Kesari, K.K. and Mukherjee, S., 2024. Editorial: Hormonal imbalance-associated oxidative stress and protective benefits of nutritional antioxidants. Frontiers in Endocrinology, 15, p.1368580. (Sahoo DK as corresponding author)
  9. Sahoo, D.K., Wong, D., et al., 2024. Exploring the role of antioxidants in sepsis-associated oxidative stress: a comprehensive review. Frontiers in Cellular and Infection Microbiology, 14, p.1348713. (Sahoo DK as a co-corresponding author; in the top 1% in the academic field of Microbiology for May/June 2025) (https://www.webofscience.com/wos/woscc/summary/fa178f06-e29d-4290-9956-83ac37d4b52d-018622debf/relevance/1)
  10. Turicea, B., Sahoo, D.K., Allbaugh, R.A., Stinman, C.C., Kubai, M.A., 2024. Novel treatment of infectious keratitis in canine corneas using ultraviolet C (UV-C) light. Veterinary Ophthalmology. 2024;00:1–15. https://doi.org/10.1111/vop.13265.
  11. Shah, H., …, Sahoo, D. K., Jergens, A. E., et al., 2024. Decoding the Gut Microbiome in Companion Animals: Impacts and Innovations. Microorganisms, 12(9), 1831; https://doi.org/10.3390/microorganisms12091831.
  12. Stewart, A.S., Kopper, J.J., ….., Sahoo, D.K., et al., 2024. Assessment of equine intestinal epithelial junctional complexes and barrier permeability using a monolayer culture system. Front. Vet. Sci. 11:1455262. https://doi.org/10.1039/D4RA06117A.
  13. Sahoo, D.K., Heilmann, R.M., …., Wong, D. and Jergens, A.E., 2023. Oxidative stress, hormones, and effects of natural antioxidants on intestinal inflammation in inflammatory bowel disease. Frontiers in Endocrinology, 14, p.1217165. (Sahoo DK as a co-corresponding author; in the top 0.1% in the academic field of Clinical Medicine for May/June 2025) (https://www.webofscience.com/wos/woscc/summary/b812c24c-0b9c-4ce7-8b22-e88de9aead56-018622d5a0/relevance/1)
  14. Sahoo, D.K., …., Jergens, A.E., et al., 2023. Canine intestinal organoids as a novel in vitro model of intestinal drug permeability: A proof-of-concept study. Cells, 12(9), p.1269.
  15. Sahoo DK, Allenspach K, et al., 2023. Synbiotic-IgY Therapy Modulates the Mucosal Microbiome and Inflammatory Indices in Dogs with Chronic Inflammatory Enteropathy: A Randomized, Double-Blind, Placebo-Controlled Study. Veterinary Sciences. 2023; 10(1):25. https://doi.org/10.3390/vetsci10010025 (Sahoo DK as a co-corresponding author)
  16. Sahoo, D.K., Borcherding, D.C., Chandra, L., Jergens, A.E., et al., 2022. Differential transcriptomic profiles following stimulation with lipopolysaccharide in intestinal organoids from dogs with inflammatory bowel disease and intestinal mast cell tumor. Cancers, 14(14), p.3525. (Sahoo DK as a co-corresponding author)
  17. Sahoo DK, Chainy GB. Hormone-linked redox status and its modulation by antioxidants. Vitamins and Hormones. 2023 Jan 13;121:197-246. (Sahoo DK as the corresponding author).
  18. Subaramaniyam, U., …., Ramalingam, N. and Sahoo, D.K., 2023. Effects of microplastics, pesticides and nano-materials on fish health, oxidative stress and antioxidant defense mechanism. Frontiers in Physiology, 14, p.1217666. (Sahoo DK as a co-corresponding author; As of May/June 2025, this highly cited paper received enough citations to place it in the top 1% of the academic field of Biology & Biochemistry based on a highly cited threshold for the field and publication year) (https://www.webofscience.com/wos/woscc/summary/805454b6-9133-48a5-9692-c30f9db3e703-018622b744/relevance/1)