Ganwu Li

MS, PhD
Education & Certifications  

PhD, 2005, Veterinary Microbiology, College of Veterinary Medicine, Berlin Free University, Berlin, Germany
MS, 1999, Veterinary Microbiology College of Veterinary Medicine, Nanjing Agricultural University Nanjing, China
BVSc, 1994, Veterinary Medicine College of Veterinary Medicine, Nanjing Agricultural University Nanjing, China

Research Focus & Interests  

Molecular diagnostics and diagnostic medicine, viral and bacterial genomic epidemiology, pathogen-host interactions, bacterial genetics and pathogenesis

Memberships  

American Society for Microbiology
American Association of Veterinary Laboratory Diagnosticians
American Veterinary Medical Association
American Association of Avian Pathologists

Selected Publications  

Qi Chen, Phillip C Gauger, Molly R Stafne, Joseph T Thomas, Darin M Madson, Haiyan Huang, Ying Zheng, Ganwu Li, Jianqiang Zhang. Pathogenesis comparison between the United States porcine epidemic diarrhea virus prototype and S-INDEL-variant strains in conventional neonatal piglets. Journal of General Virology, In Press, 2016 Feb 3. doi: 10.1099/jgv.0.000419. [Epub ahead of print].

*Bryon Nicholson, Aaron C. West, Paul Mangiamele, Nicolle Barbieri, Kathy Mou, Yvonne Wannemuehler, Lisa K. Nolan, Catherine M. Logue and Ganwu Li. Genetic Characterization of ExPEC-like Virulence Plasmids among a Subset of NMEC. PLoS One, 2016 Jan 22; 11(1):e0147757. doi: 10.1371/journal.pone.0147757.

Lisa K. Nolan, Ganwu Li, Catherine M.  Logue. Origin and Dissemination of Antimicrobial Resistance among Uropathogenic Escherichia coli. Microbiology Spectrum.  2015 Oct; 3(5). doi: 10.1128/microbiolspec.UTI-0007-2012

Bora Nam, Ganwu Li, Ying Zheng, Jianqiang Zhang, Kathleen M. Shuck, Peter J. Timoney, Udeni B. R. Balasuriya. Complete Genome Sequence of Noncytopathic Bovine Viral Diarrhea Virus 1 Contaminating a High-Passage RK-13 Cell Line. Genome Announcement. 2015 1;3(5). pii: e01115-15. doi: 10.1128/genomeA.01115-15.

Jianqiang Zhang, Pablo Piñeyro, Qi Chen, Ying Zheng, Ganwu Li, Christopher Rademacher, Rachel Derscheid, Baoqing Guo, Kyoung-Jin Yoon, Darin Madson, Phillip Gauger, Kent Schwartz, Karen Harmon, Daniel Linhares, Rodger Main. Full-Length Genome Sequences of Senecavirus A from Recent Idiopathic Vesicular Disease Outbreaks in United States Swine. Genome Announcement, 2015, 12; 3 (6). pii: e01270-15. doi: 10.1128/genomeA.01270-15.

*Fengwei Zhang, Chunxia An, Yinli Bao, Xuefeng Zhao, Jernigan RL, Lithio A, Nettleton D, Li L, Wurtele ES, Lisa k. Nolan, Chengping Lu, Ganwu Li.  ArcA Controls Metabolism, Chemotaxis, and Motility Contributing to the Pathogenicity of Avian Pathogenic Escherichia coli. Infection and Immunity. 2015 Sep; 83(9): 3545-54.

*Nicolle L. Barbieri, Bryon Nicholson, Ashraf Hussein, Wentong Cai, Yvonne M. Wannemuehler, Giuseppe Dell'Anna, Catherine M. Logue, Fabiana Horn, Lisa K. Nolan, and Ganwu Li. FNR Regulates the Expression of Important Virulence Factors Contributing to the Pathogenicity of Uropathogenic Escherichia coli. Infection and Immunity. 2014 Dec; 82(12): 5086-98. doi: 10.1128/IAI.02315-14.

*Ganwu Li, Chen Q, Harmon KM, Yoon KJ, Schwartz KJ, Hoogland MJ, Gauger PC, Main RG, Zhang J. Full-Length Genome Sequence of Porcine Deltacoronavirus Strain USA/IA/2014/8734. Genome Announcement. 2014 Apr 10;2(2). pii: e00278-14. doi: 10.1128/genomeA.00278-14.

Chen Q, Li Ganwu, Stasko J, Thomas JT, Stensland WR, Pillatzki AE, Gauger PC, Schwartz KJ, Madson D, Yoon KJ, Stevenson GW, Burrough ER, Harmon KM, Main RG, Zhang J. Isolation and Characterization of Porcine Epidemic Diarrhea Viruses Associated with the 2013 Disease Outbreak among Swine in the United States. Journal of Clinical Microbiology. 2014 Jan; 52(1): 234-43. doi: 10.1128/ JCM. 02820- 13.

*Wentong Cai, Yvonne Wannemuehler, Giuseppe Dell'Anna, Bryon Nicholson, Nicolle L. Barbieri, Subhashinie Kariyawasam, Yaping Feng, Catherine M. Logue, Lisa K. Nolan, Ganwu Li. A Novel Two-Component Signalling System Facilitates Uropathogenic Escherichia coli’s Ability to Exploit Abundant Host Metabolites. PLoS Pathogens 2013, 9(6): e1003428. doi:10.1371/journal.ppat.1003428.

Hussein AH, Ghanem IA, Eid AA, Ali MA, Sherwood JS, Li Ganwu, Nolan LK, Logue CM. Molecular and phenotypic characterization of Escherichia coli isolated from broiler chicken flocks in Egypt. Avian Dis. 2013 Sep; 57(3):602-11.

Mangiamele P, Nicholson B, Wannemuehler Y, Seemann T, Logue CM, Li Ganwu, Tivendale KA, Nolan LK. Complete genome sequence of the avian pathogenic Escherichia coli strain APEC O78. Genome Announcement. 2013 Mar 21; 1 (2): e0002613. doi: 10.1128/genomeA.00026-13.

Peter Schierack, Stefan Rödiger, Christoph Kuhl, Rico Hiemann, Ganwu Li, Jörg Weinreich, Enrico Berger, Lisa K. Nolan, Bryon Nicholson, Antje Römer, Ulrike Frömmel and Christian Schröder. Characterization of porcine E. coli isolates by a new screening method. PLOS One, 2013 Apr 26;8(4):e59242. doi: 10.1371/journal.pone.0059242.

Catherine M. Logue, Curt Doetkott, Paul Mangiamele, Yvonne M. Wannemuehler, Timothy J. Johnson, Kelly A. Tivendale, Ganwu Li, Julie S. Sherwood and Lisa K. Nolan: Refining the Definition of the NMEC Subpathotype. Applied and Environmental Microbiology, 2012; 78 (16): 5824-30.

Ganwu Li, Wentong Cai, Ashraf Hussein, Yvonne Wannemuheler, Catherine M. Logue, and Lisa K Nolan. Proteome response of a zoonotic ExPEC to human and avian sera. Journal of Proteomics, 2012; 75 (15): 4853-62.

Ganwu Li, Subhashinie Kariyawasam, Kelly A. Tivendale, Yvonne Wannemuehler, Christa Ewers, Lothar H. Wieler, Catherine M. Logue, and Lisa K. Nolan: tkt1, Located on a Novel Pathogenicity Island, is Prevalent in Avian and Human Extraintestinal Pathogenic Escherichia coli. BMC Microbiol. 2012 Apr 3;12 (1):51.

Ganwu Li, Kelly Tivendale, Peng Liu, Yaping Feng, Yvonne Wannemuheler, Wentong Cai, Paul Mangiamele, Timothy J. Johnson, Chaeles W. Penn, and Lisa K Nolan. Transcriptome Analysis of Avian Pathogenic Escherichia coli in Chicken Serum Reveals Adaptive Responses to Systemic Infection. Infection and Immunity, 2011, 79 (5): 1951-1960.

Kelly A. Tivendale, Catherine M. Logue, Subhashinie Kariyawasam, Dianna Jordan, Ashraf Hussein, Ganwu Li, Yvonne Wannemuehler, and Lisa K. Nolan. Avian-Pathogenic Escherichia coli Strains Are Similar to Neonatal Meningitis E. coli Strains and Are Able To Cause Meningitis in the Rat Model of Human Disease. Infection and Immunity, 2010, 78 (8): 3412-3419.

Ganwu Li, Yaping Feng, Subhashinie Kariyawasam, Kelly A. Tivendale, Yvonne Wannemuehler, Fanghong Zhou, Catherine M. Logue and Lisa K. Nolan.  AesA is a Novel Autotransporter and Virulence Factor of Avian Pathogenic Escherichia coli. Infection and Immunity, 2010, 78(3): 898-906.