Bradley Blitvich

B.Sc., Ph.D.
Associate Professor
2116 Vet Med
Education & Certifications  

1991: B.Sc., The University of Western Australia, Perth, Australia

1996: Ph.D., The University of Western Australia, Perth, Australia

1997-1998: Post-doc, Queen Elizabeth II Medical Center, Perth, Australia

1999-2006: Post-doc, Colorado State University, Fort Collins, Colorado, USA

2006-2011: Assistant Professor, Iowa State University, Ames, Iowa, USA

2011-present: Associate Professor, Iowa State University, Ames, Iowa, USA 


Molecular Viology (VMPM 608)

Graduate Student Seminar Series (VMPM 604)

Research Focus & Interests  

Dr. Blitvich specializes in arthropod-borne viruses (arboviruses) and their mosquito vectors. His primary research focus is to determine the impact of arboviruses, such as West Nile virus and CacheValley virus, on human and veterinary animal health in the United States and Mexico. Another research focus is to identify the genetic determinants that condition the differential host ranges, transmission dynamics and tropisms of insect-specific and vertebrate-mosquito transmitted flaviviruses.


1998 – present: American Society for Virology (Life Member)

2001 – present: American Society for Tropical Medicine and Hygiene (Member)

Selected Publications  

Full publication list on PubMed

Peer-reviewed publications (last 8 years only):

* Loy DS, Liu S, Mogler MA, Loy JD, Blitvich BJ, Bartholomay LC. Characterization of newly revealed sequences in the Infectious Myonecrosis virus genome in Litopenaeus vannamei. (Accepted).

* Bisanzio D, McMillan JR, Gonzalves-Barreto J, Blitvich BJ, Mead DG, O’Connor J, Kitron U. Evidence for West Nile virus spillover into the squirrel population in Atlanta, USA. Vector-Borne and Zoonotic Diseases. (Accepted).

* Johnson GD, Bahnson CS, Ishii P, Cochrane ZN, Hokit DG, Plummer PJ, Bartholomay LC, Blitvich BJ. Monitoring sheep and Culicoides midges in Montana for evidence of Bunyamwera serogroup virus infection. Veterinary Record. 2014, In press.

* Thompson NN, Auguste AJ, Travassos da Rosa APA, Carrington CVF, Blitvich BJ, Chadee DD, Tesh RB, Weaver SC, Adesiyun AA. Seroepidemiology of selected alphaviruses and flaviviruses in bats in Trinidad. Zoonoses and Public Health. 2015, Epub Ahead of Print.

* Saiyasombat R, Carrillo-Tripp J, Miller WA, Bredenbeek PJ, Blitvich BJ. Substitution of the premembrane and envelope protein genes of Modoc virus with the homologous sequences of West Nile virus generates a chimeric virus that replicates in vertebrate but not mosquito cells. Virology Journal. 2014. 11:150.

* Machain-Williams C, Dzul Rosado AR, Yeh-Gorocica AB, Ruz-Cuevas K, Noh-Pech H, Salazar-Sanchez Ma. I, Castro-Mussot ME, Reyes-Solis G, Garcia-Rejon J, Puerto-Manzano I, Blitvich BJ. Detection of hand, foot and mouth disease in the Yucatan Peninsula of Mexico. Infectious Disease Reports. 2014; Dec 9;6(4):5627.

* Machain-Williams C, López-Uribe M, Aguilar-Talavera L, Carrillo-Navarrete J, Vera-Escalante L, Puerto-Manzano F, Ulloa A, Farfán-Ale JA, Garcia-Rejon J, Blitvich BJ, Loroño-Pino MA. Serological evidence of flavivirus infection in bats in the Yucatan Peninsula of Mexico. Journal of Wildlife Diseases. 2013. 49(3):684-9.

* Sanchez-Casas RM, Alpuche-Delgado RH, Blitvich BJ, Diaz-Gonzalez EE, Ramirez-Jimenez R, Zarate-Nahon EA, Sanchez-Rodriguez OS, Laguna-Aguilar M, Alvarado-Moreno M, Ibarra-Juarez LA, Medina de la Garza CE, Lorono-Pino MA, Mis-Avila P, Fernandez-Salas I.  Detection of dengue virus serotype 2 in Aedes aegypti in Quintana Roo, Mexico, 2011. Southwestern Entomologist. 2013, 38(1):109-117.

* Randall NJ, Blitvich BJ, Blanchong JA. Association between agricultural land use and West Nile virus seroprevalence in Iowa birds. Journal of Wildlife Diseases. 2013. 49(4) 869-878.

* Hobson-Peters J, Lu J, Yam A, Kurucz N, Walsh S, Prow NA, Davis SS, Weir R, Melville L, Hunt N, Webb R, Blitvich BJ, Whelan P, Hall RA. A new insect-specific flavivirus from northern Australia suppresses replication of Kunjin virus and Murray Valley encephalitis virus in co-infected mosquito cells. PLOS One. 2013. Epub ahead of print.

* Machain-Williams C, Padilla-Paz SE, Weber M, Cetina-Trejo R, Juarez-Ordaz RA, Loroño-Pino MA, Ulloa A, Wang C, Garcia-Rejon J, Blitvich BJ. Antibodies to West Nile virus in wild and farmed crocodiles in southeastern Mexico. Journal of Wildlife Diseases. 2013. 49(3):690-3.

* Blitvich BJ, Saiyasombat R, Dorman KS, Garcia-Rejon JE, Farfan-Ale JA, Loroño-Pino MA. Sequence and phylogenetic data indicate that an orthobunyavirus recently detected in the Yucatan Peninsula of Mexico is a novel reassortant of Potosi and Cache Valley viruses. Archives of Virology. 2012 157(6):1199-204.

* Blitvich BJ, Staley M, Loroño-Pino MA, Garcia-Rejon JE, Farfan-Ale JA, Dorman KS. Identification of a novel subtype of South River virus (family Bunyaviridae). Archives of Virology. 2012 157(6):1205-9.

* Randall NJ, Blitvich BJ, Blanchong JA. Wildlife rehabilitation centers in surveillance and monitoring for pathogen activity: a case study with West Nile virus. Journal of Wildlife Diseases. 2012. 48(3):646-53.

* Ibarra-Juarez L, Eisen L, Bolling B, Beaty BJ, Blitvich BJ, Sanchez-Casas RM, Ayala-Sulca YO, Fernandez-Salas I. Detection of West Nile virus-specific antibodies in horses and nucleic acid in mosquitoes, from Nuevo Leon State, northern Mexico, 2006-2007. Medical and Veterinary Entomology. 2012. 26(3):351-4.

* Blitvich BJ, Loroño-Pino MA, Garcia-Rejon JE, Farfan-Ale JA, Dorman KS. Nucleotide sequencing and serologic analysis of Cache Valley virus isolates from the Yucatan Peninsula. Virus Genes. 2012. 45(1):176-80.

* Blitvich BJ, Saiyasombat R, Talavera-Aguilar LG, Garcia-Rejon JE, Farfan-Ale JA, Machain-Williams C, Loroño-Pino MA. Orthobunyavirus antibodies in humans, Yucatan Peninsula, Mexico. Emerging Infectious Diseases. 2012. 18(10):1629-32.

* Hall RA, Blitvich BJ, Johansen CA, Blacksell SD. Advances in arbovirus surveillance, detection and diagnosis. J Biomed Biotechnol. 2012 Epub ahead of print.

* Thompson NN, Auguste AJ, Coombs D, Weaver SC, Blitvich BJ, Carrington CCV, Travassos da Rosa AP, Wang E, Chadee DC, Drebot MA, Tesh RB, Adesiyun AA. Seropositivity of arboviruses in livestock and wildlife in Trinidad. Vector-Borne and Zoonotic Diseases. Vector Borne Zoonotic Dis. 2012. 12(11):969-78.

* Blitvich BJ, Saiyasombat R, Travassos da Rosa APA, Tesh RB, Calisher CH, Garcia-Rejon JE, Farfan-Ale JA, Loroño RE, Bates A, Loroño-Pino MA. Orthobunyaviruses, a common cause of infection of livestock in the Yucatan Peninsula of Mexico. Am J Trop Med Hyg. 2012. 87(6):1132-9.

* Ledermann JP, Lorono-Pino MA, Ellis C, Shaw K, Blitvich BJ, Beaty BJ, Bowen RA, Powers AM. Sequential flavivirus infections of equines: detection of host antibody response and comparison of widely-used diagnostic techniques. Clin Vaccine Immunol. Clin Vaccine Immunol. 2011 18(4):580-7.

* Foy BD, Kobylinski KC, Chilson-Foy JL, Blitvich BJ, Travassos Da Rosa A, Haddow AD, Lanciotti RS, Tesh RB. Probable non-vector-borne transmission of Zika virus in Colorado, USA.  Emerg Infect Dis. 2011 17(5):880-2.

* Hobson-Peters J, Arévalo C, Cheah WY, Blitvich BJ, Tan SE, Sandis A, Nazario LA, Hernández JL, Toye P, Hall RA. Detection of antibodies to West Nile virus in horses, Costa Rica, 2004. Vector Borne Zoonotic Dis. 2011 11(8):1081-4.

* Saiyasombat R, Bolling BG, Brault AC, Bartholomay LC, Blitvich BJ. Evidence of Efficient Transovarial Transmission of Culex flavivirus by Culex pipiens (Diptera: Culicidae). J Med Entomol. 2011 48(5):1031-8.

* Farfan-Ale JA, Loroño-Pino MA, Garcia-Rejon JE, Soto V, Lin M, Staley M, Dorman KS, Bartholomay LC, Hovav E, Blitvich BJ. Detection of flaviviruses and orthobunyaviruses in mosquitoes in the Yucatan Peninsula of Mexico in 2008. Vector Borne Zoonotic Dis. 2010. 10(8):777-83.

* Saiyasombat R, Dorman KS, Bartholomay LC, Garcia-Rejon JE, Loroño-Pino MA, Farfan-Ale JA, Blitvich BJ. Isolation and sequence analysis of Culex flavivirus from Culex interrogator and Culex quinquefasciatus in the Yucatan Peninsula of Mexico. Arch Virol. 2010. 155(6):983-6.

* Root JJ, Bentler KT, Sullivan HJ, Blitvich BJ, McLean RG, Franklin AB. A longitudinal investigation of antibody responses in raccoons naturally exposed to multiple subtypes of influenza A virus. Vector Borne Zoonotic Dis. 2010. 10(8):821-3.

* Staley M, Dorman KS, Bartholomay LC, Fernández-Salas I Farfan-Alé, JA, Loroño-Pino MA, Garcia-Rejon JE, Ibarra-Juarez L, Blitvich BJ. Universal primers for the amplification and sequence analysis of actin-1 from diverse mosquito species. J Am Mosq Control Assoc. 2010. 26(2):214-8.

* Seiler BM, Yoon KJ, Andreasen CB, Block SM, Marsden S, Blitvich BJ. Seroprevalence for influenza A virus (H1 and H3) in domestic animals in Iowa. Vet Record. 2010. 167(18):705-7.

* Garcia-Rejon JE. Blitvich BJ, Farfan-Ale JA, Loroño-Pino MA, Chi Chim WA, Flores-Flores LF,Rosado-Paredes E,Baak-Baak C, Perez-Mutul J, Suarez-Solis V, Fernandez-Salas I, Beaty BJ. Host-feeding preference of Culex quinquefasciatus in Yucatan State, Mexico. J. Insect Sci. 2010 Mar;10:32.

* Blitvich BJ, Ibarra-Juarez LA, Cortes-Guzman AJ, Root JJ,Franklin AB, Sullivan HJ, Fernandez-Salas I. Seroprevalence for equine influenza virus in northeast and southern Mexico. Vet. Record. 2010. 166(18):565-6.

* Rios-Ibarra C, Blitvich BJ, Farfan-Ale J, Ramos-Jimenez J, Muro-Escobedo S, Ortiz-López R, Torres-López E, Rivas-Estilla AM. Fatal human case of West Nile virus disease, Mexico, 2009. Emerg Infect Dis. 2010 16(4):741-3.

* Firth AE, Blitvich BJ, Wills NM, Miller CL, Atkins JF. Evidence for ribosomal frameshifting and a novel overlapping gene in the genomes of insect-specific flaviviruses. Virology. 2010. 399(1):153-66.  

* Tiawsirisup S, Blitvich BJ, Tucker BJ, Halbur HG, Bartholomay LC, Rowley WA, Platt KB. Susceptibility of fox squirrels (Sciurus niger) to West Nile virus by oral exposure. Vector Borne Zoonotic Dis. 2010. 10(2):207-9.

* Loroño-Pino MA, Farfan-Ale JA, Garcia-Rejon JE, Lin M, Rosado-Paredes E, Puerto FI, Bates A, Root JJ,Franklin AB, Sullivan HJ, Blitvich BJ. Antibodies to Influenza and West Nile viruses in horses in Mexico. Vet. Record. 2010. 166(1):22-3.

* Melian EB, Hinzman E, Nagasaki T, Firth AE, Wills NM, Nouwens AS, Blitvich BJ, Leung J, Funk A, Atkins JF, Hall R, Khromykh AA. NS1' of Flaviviruses in the Japanese Encephalitis Virus Serogroup Is a Product of Ribosomal Frameshifting and Plays a Role in Viral Neuroinvasiveness. J Virol. 2010. 84(3):1641-7.

* Garza-Rodríguez ML, Rodríguez-Rodriguez DR, Blitvich BJ, Reyes MA, Fernández-Salas I, Jimenez JR, Farfán-Ale JA, Tamez RC, Martinez-Longoria C, Tavitas-Aguilar MI, Rivas-Estilla AM. Serologic surveillance for West Nile virus and other flaviviruses in febrile patients, encephalitic patients and asymptomatic blood donors in northern Mexico. Vector Borne Zoonotic Dis. Vector Borne Zoonotic Dis. 2010. 10(2):151-7.

* Blitvich BJ, Ibarra-Juarez L, Tucker BJ, Rowley WA, Platt KB. Antibodies to West Nile virus in raccoons and other wild peridomestic mammals in Iowa. J. Wildlife Dis. 2009. 45:1163-8.

* Dunphy BM, Tucker BJ, Petersen M, Blitvich BJ, Bartholomay LC.The arrival and establishment of Aedes japonicus japonicus (Diptera: Culicidae) in Iowa, USA. J. Med. Ent. 2009. 46(6):1282-9.

* Soto V, Dorman KS, Farfan-Ale JA, Loroño-Pino MA, Garcia-Rejon JE, Blitvich BJ. Complete nucleotide sequence of the small and medium RNA genome segments of Kairi virus (family Bunyaviridae). Arch. Virol. 2009. 154(9): 1555-8.

* Blitvich BJ, Lin M, Dorman KS, Soto V, Hovav E, Tucker BJ, Staley M, Platt KB, Bartholomay LC. Genomic sequence and phylogenetic analysis of Culex flavivirus, an insect-specific flavivirus, isolated from Culex pipiens in Iowa. J. Med Ent. 2009. 46(4): 934-41.

* Sullivan HJ, Blitvich BJ, VanDalen K, Bentler KT, Franklin AB, Root JJ. Evaluation of an epitope-blocking enzyme-linked immunosorbent assay for the detection of antibodies to Influenza A virus in domestic and wild avian and mammalian species. J. Virol Methods. 2009. 161:141-6.

* Farfan-Ale JA, Loroño-Pino MA, Garcia-Rejon JE, Hovav E, Powers AM, Lin M, Dorman KS, Platt KB, Bartholomay LC, Soto V, Beaty BJ, Lanciotti RS, Blitvich BJ. Detection of RNA from a novel West Nile-like virus and high prevalence of an insect-specific flavivirus in mosquitoes in the Yucatan Peninsula of Mexico. Am J Trop Med Hyg. 2009. 80(1):85-95.

* Loroño-Pino MA, Farfan-Ale JA, Blitvich BJ, Beebe JL, Jarman RG, Beaty BJ. Evaluation of an Epitope-Blocking Enzyme-Linked Immunosorbent Assay for the Diagnosis of West Nile Virus Infections in Humans. 2009. 16(5):749-55.

* Blitvich BJ. Transmission dynamics and changing epidemiology of West Nile virus. Anim Health Res Rev. 2008 9(1):71-86.

* Platt KB, Tucker BJ, Halbur PG, Blitvich BJ, Fabiosa FG, Mullin K, Parikh GR, Kitikoon P, Bartholomay LC, Rowley WA. Fox squirrels (Sciurus niger) develop West Nile virus viremias sufficient for infecting select mosquito species. Vector Borne Zoonotic Dis. 2008 8(2):225-33.

* Reese SM, Blitvich BJ, Blair CD, Geske D, Beaty BJ, Black WC. Potential for La Crosse virus segment reassortment in nature. Virol. J. 2008 5(1):164.

* Beck ET, Blair CD, Black WC, Beaty BJ, Blitvich BJ. Alternative splicing generates multiple transcripts of the Inhibitor of Apoptosis Protein 1 in Aedes and Culex sp. mosquitoes. Insect Mol Biol. 2007 37(11):1222-33.

* Platt KB, Tucker BJ, Halbur PG, Tiawsirisup S, Blitvich BJ, Fabiosa FG, Bartholomay LC, Rowley WA. West Nile virus viremia in eastern chipmunks (Tamias striatus) sufficient for infecting different mosquitoes. Emerg Infect Dis. 2007. 13(6):831-7.

* Sondgeroth K, Blitvich BJ, Blair CD, Terwee J, Junge R, Sauther M, VandeWoude S. Assessing Flavivirus, Lentivirus, and Herpesvirus Exposure in wild Lemur catta in southwestern Madagascar. J. Wildlife Dis. 2007. 43(1):40-7.

* Li Q, Li H, Blitvich BJ, Zhang J. The Aedes albopictus inhibitor of Apoptosis 1 gene protects vertebrate cells from bluetongue virus-induced apoptosis. Insect Mol Biol. 2007. 16(1):93-105.