Luis Gimenez-Lirola

MS, PhD
Associate Professor
Veterinary Diagnostic Laboratory
Veterinary Preventive Medicine Graduate Programs
Vet Diagnostic & Production Animal Medicine
5152947025
2652 Patterson Hall
ISU Directory Link
Education & Certifications  
  • PhD, Molecular and Cellular Biology (Cum Laude), University of Jaén (Jaén, Spain), 2009.
  • MS, Occupational Risk Prevention, Institute Universitary of Science & Technology (Barcelona Spain), 2005.
  • MS, Biochemistry, University of Granada (Granada, Spain), 2002.
  • BS, Biochemistry, University of Granada (Granada, Spain), 2002.
Teaching  
  • VDPAM 455 - Diagnostic Laboratory Practicum
  • VDPAM 560 - Ecology of Infectious Diseases
  • VDPAM 562X - Applied Diagnostic Technologies
Research Focus & Interests  

Dr. Gimenez-Lirola has over 20 years of experience in the field of infectious diseases. His background blended in the interface of academia-industry. Overall, Dr. Gimenez-Lirola’s research activity is commitment to the highest standards in “science with practice” towards conducting original research to design, develop, and implement new in vitro pathogen-specific detection tools as well as the development of in vitro/ex vivo culture models to investigate the immunopathogenesis of viral diseases with particular emphasis on swine. Dr. Gimenez-Lirola’s group is focused on the characterization of re/emerging animal (PEDV, PHEV, PDCoV, PHEV) and human (SARS-like CoVs, NL63, HEC, etc) coronaviruses. His applied research has been translated into over 90 peer reviewed and 40 non-refereed articles, 524 proceedings, abstracts and oral presentations.

Honors & Awards  
  • ISU CVM Early Career Achievement in Research Award 2022.
  • ISU CVM Team of the Year Award 2021. Team member of the ISU VDL’s Public Health Testing Services Unit (COVID-19 antibody tests validation and onboarding).
Leadership/Committees/Council  
  • Andalusian Public Health System Biobank (Granada, Spain), Scientific Committee.
  • Journal Pathogens, Guess Editor.
  • 19th International Symposium of the World Association of Veterinary Laboratory Diagnosticians (ISWAVLD), Committee Member.
  • North American PRRSV symposium (Chicago), Scientific Committee.
  • Veterinary Diagnostic and Production Animal Medicine Graduate Program, External Mentor – Annual reviews.
  • College Core Lab Planning Committee, Member.
  • CVM Research Advisory Committee at ISU, Member.
  • CVM Research Advisory Committee for Grad Student Scholarship Nominee at ISU, Member.
  • CVM Seed Grant proposals Committee at ISU, Member.
  • CVM International Committee, Member.
  • VDPAM Graduate Studies and Research Committee at ISU, Member.
  • Team Science Academy Program, Participant.
  • National Science Foundation Corps (I-Corps) at ISU, Participant.
  • Frontiers in Microbiology, Review Editor on the Editorial Board of Virology.
  • Journal of Veterinary Sciences, Guest Associated Editor.
  • Frontiers Veterinary Science, Guest Associate Editor in Veterinary Epidemiology and Economics.
  • Journal Pathogens, Topic Editorial Board Member.
  • Journal of Veterinary Infectious Diseases Frontiers Veterinary Science, Review Editor in Veterinary Infectious Diseases.
  • Journal of the American Association of Veterinary Laboratory Diagnosticians, Editorial Board Member.
Memberships  
  • Team Science Academy Program.
  • American Association of Swine Veterinarians.
  • National Swine Improvement Federation, Member.
  • American Society for Virology.
  • Iowa Veterinary Medical Association.
  • USDA North Central Regional Project 229 “Detection and control of PRRSV and emerging viral diseases of swine”.
  • American Society for Microbiology.
  • American Association of Veterinary Laboratory Diagnosticians.
Selected Publications  

https://scholar.google.com/citations?user=c8J-a1QAAAAJ&hl=en&oi=ao

  • Castillo G, Mora-Diaz JC, Nelli RK, Giménez-Lirola LG.  (2022).  Human air-liquid-interface organotypic airway cultures express significantly more ACE2 receptor protein and are more susceptible to HCoV-NL63 infection than monolayer cultures of primary respiratory epithelial cells.  Microbiol Spectrum. 2022 Jul 12:e0163922. doi: 10.1128/spectrum.01639-22.
  • Yongming Sang, Miller LC, Nelli RK, Gimenez-Lirola LG.  (2021).  Harnessing Organoid Models for Virological Studies in Animals: A Cross-Species Perspective.  Front Microbiol.  2021 Sep 16;12:725074.  doi: 10.3389/fmicb.2021.725074.  eCollection 2021.
  • Mora-Díaz JC, Piñeyro P, Rauh R, Nelson W, Sankoh Z, Gregg E, Carrillo-Ávila JA, Shen H, Nelli RK, Zimmerman J, Giménez-Lirola LG*. (2021). Porcine hemagglutinating encephalomyelitis virus infection in vivo and ex vivo. Journal Virology. 2021 May 24;95(12):e02335-20. doi: 10.1128/JVI.02335-20. Print 2021 May 24.
  • Mora-Díaz JC, Piñeyro PE, Shen H, Schwartz KJ, Vannucci F, Li G, Arruda B, Giménez-Lirola LG*. (2020). Isolation of PCV3 from perinatal and reproductive cases of PCV3-associated disease and in vivo characterization of PCV3 replication in CD/CD growing pigs. Viruses, 12(2):219.
  • Magtoto R, Poonsuk K, Baum D, Zhang J, Chen Q, Ji J, Piñeyro P, Zimmerman J, Giménez-Lirola LG*. (2019). Evaluation of the serologic cross-reactivity between transmissible gastroenteritis coronavirus and porcine respiratory coronavirus using commercial blocking ELISA kits. mSphere, 4:2.
  • Mora-Díaz JC, Piñeyro PE, Houston E, Zimmerman J, Giménez-Lirola LG.  (2019).  Porcine hemagglutinating encephalomyelitis virus: A review.  Frontiers Veterinary Sciences, 6:53. 
  • Poonsuk K, Zhang J, Chen C, Gonzalez W, Correa da Silva Carrion L, Yaxuan S, Wang C, Main R, Zimmerman J, Giménez-Lirola LG*. (2017). Quantifying the effect of lactogenic antibody on porcine epidemic diarrhea virus infection in neonatal piglets. Veterinary Microbiology, 197:83-92.
  • Giménez-Lirola LG, Zhang J, Carrillo JA, Chen Q, Magtoto R, Poonsuk K, Baum D, Piñeyro P, Zimmerman J. (2017). Reactivity of anti-PEDV structural protein antibodies to porcine enteric coronaviruses: diagnostic implications. Journal Clinical Microbiology, 55(5):1426-1436.
  • Giménez-Lirola LG*, Mur L, Rivera B, Mogler M, Lizano S, Goodell C, Harris DL, Gallardo C, Arias M, Rowland RRR, Sánchez-Vizcaíno JM, Zimmerman J. (2016). Detection of African swine fever virus antibodies in serum and oral fluid specimens from acutely infected animals using a recombinant protein 30 (rp30) indirect ELISA. PLoS One, 11(9).
  • Giménez-Lirola LG*, Baum D, C Rademacher C, Linhares D, Harmon K, Rotolo M, Sun Y, Baum D, J Zimmerman J, Pineyro P. (2016). Serological and Molecular detection of Senecavirus A associated with an outbreak of Swine Idiopathic Vesicular Disease and Neonatal Mortality. Journal Clinical Microbiology, 54(8):2082-9.