Mark Lyte

W. Eugene Lloyd Chair in Toxicology
2158 Patterson Hall
Education & Certifications  

BS - Medical Technology - Fairleigh Dickinson University, NJ - 06/1976

MS - Membrane Research - Weizmann Institute of Science, Israel - 05/1979

PhD - Cell Biology/Membrane Research - Weizmann Institute of Science, Israel - 07/1983

Postdoctoral - Immunology - Medical College of Virginia, VA - 05/1985

Postdoctoral - Clinical Immunology - University of Pittsburgh, PA - 11/1986


Honors & Awards  
1979-1983 Weizmann Institute of Science Pre-Doctoral Fellowship
1983-1984: National Cancer Institute Training Grant
1984-1986: National Institutes of Health Individual Postdoctoral Fellowship Award
1987: University of Wisconsin Research Incentive Program Award
2002: Joseph Susman Memorial Award in Surgical Infectious Disease Research by the combined Surgical Infection Societies of North America and Europe
2008: NIH Pioneer Award Finalist
2014: NIH Distinguished Speaker Award 
2017: Recipient of 2017 Dr. Leo K. Bustad Distinguished Lecture Series Award, Washington State University Veterinary School
2017: Appointment as Eugene W. Lloyd Endowed Chair in Toxicology


Selected Publications  

Full publication list on PubMed

Lyte, M. and Brown, D.R. Evidence for PMAT- and OCT-like biogenic amine transporters in a probiotic strain of Lactobacillus: Implications for interkingdom communication within the microbiota-gut-brain axis. PLoS ONE, Volume 13, Issue 1, January 2018, Article number e0191037.

Amaral, W.Z., Lubach, G.R., Proctor, A., Lyte, M., Phillips, G.J., and Coe, C.L. Low Social influences on Prevotella and the gut microbiome of young monkeys. Psychosomatic Medicine, 79:888-897, 2017.

Villageliu, D.N. and Lyte, M. Microbial endocrinology: Why the intersection of microbiology and neurobiology matters to poultry health. Poultry Science, 96:2501-8, 2017.

Amaral, W.Z., Lubach, G.R., Kapoor, A., Phillips, G.J., Lyte, M., and Coe, C.L. Low Lactobacilli abundance and polymicrobial diversity in the lower reproductive tract of female rhesus monkeys do not compromise their reproductive success. American Journal of Primatology, 2017 Oct;79(10). doi: 10.1002/ajp.22691. Epub 2017 Sep 12.

Lyte M. Microbial Endocrinology in the Pathogenesis of Infectious Disease. Microbiology Spectrum, 2016 Apr; 4(2) doi: 10.1128/microbiolspec. 

Lyte, M., Fodor, A.A., Chapman, C.D., Martin, G.C., Perez-Chanona, E., Jobin, C., and Dess, N.K. Gut microbiota and a selectively bred taste phenotype: A novel model of microbiome-behavior relationships. Psychosomatic Medicine 78:610-619, 2016. 

Lyte M et al., Resistant starch alters the microbiota-gut-brain axis: Implications for dietary modulation of behavior. PLoS One 2016 Jan 8;11(1):e0146406. doi: 10.1371/journal.pone.0146406. eCollection 2016.

Lyte M (2010a) Microbial Endocrinology: A Personal Journey. In: Lyte M, Freestone PPE (eds) Microbial endocrinology: interkingdom signaling in infectious disease and health. Springer, New York, pp 1-16

Lyte M (2014) Microbial endocrinology and the microbiota-gut-brain axis. Advances in Experimental Medicine and Biology 817:3-24.

Lyte, M. Microbial endocrinology and infectious disease in the 21st century. Trends in Microbiology, 12:14-20, 2004.

Lyte, M., Neal, C.P., Olson, B.A., Parkin, J.L., Freestone, P.P.E., Haigh, R.D., Bayston, R. and Williams, P.H. Stimulation of Staphylococcus epidermidis growth and biofilm formation by catecholamine inotropes. The Lancet 361:130-135, 2003.

Lyte, M. Microbial endocrinology: Host-microbiota neuroendocrine interactions influencing brain and behavior. Gut Microbes, 5:381-389, 2014.

Goehler, L.E., Gaykema, R.P.A., Opitz, N., Reddaway, R., Badr, N. and Lyte, M. Activation in vagal afferents and central autonomic pathways: early responses to intestinal infection with Campylobacter jejuni. Brain, Behavior and Immunity, 19:334-344, 2005.

Lyte, M. Probiotics function mechanistically as delivery vehicles for neuroactive compounds: Microbial endocrinology in the design and use of probiotics. BioEssays, 33:574-581, 2011.