Pat Halbur

DVM, MS, PhD
Professor and Chair
515-294-6970
2203A Lloyd
Education & Certifications  

Doctor of Veterinary Medicine, 1986, Iowa State University
MS (Veterinary Pathology), 1992, Iowa State University
PhD (Veterinary Pathology), 1995, Iowa State University

Research Focus & Interests  

Food animal infectious disease diagnosis and pathogenesis. Particular interest in porcine reproductive and respiratory syndrome virus, porcine circovirus, hepatitis E virus, parvovirus and other emerging diseases of pigs.

Honors & Awards  

2015: Iowa State University Award for Achievement in Intellectual Property
2014: Named to the “Masters of the Pork Industry” by the National Hog Farmer magazine.  http://viewer.zmags.com/publication/32ddd069#/32ddd069/1
2012: Iowa State University Award for Departmental Leadership
2007: Alpha Gamma Rho Agriculture Fraternity, Alumni Career Achievement Award
2004: Designated as an Honorary Iowa Master Pork Producer in 2004 in recognition of outstanding service to the Iowa swine industry.
2004: Meritorious Service Award from the Iowa Veterinary Medical Association.
2003: Pfizer Faculty Research Excellence Award.
1998: Howard W. Dunne Memorial Award for “Outstanding Service to the American Association of Swine Veterinarians and the Swine Industry”.

Leadership/Committees/Council  

President-elect, American Association of Veterinary Laboratory Diagnosticians (2015-present).
Executive Board for North Central Region AAVLD (2011-2014)
Professor and Chair, Department of Veterinary Diagnostic and Production Animal Medicine and Executive Director of the Veterinary Diagnostic Laboratory, Iowa State University College of Veterinary Medicine (2005-present)
Interim Associate Dean for Public Services and Outreach, College of Veterinary Medicine, Iowa State University (2004-2005). 
Board of Directors, American Association of Swine Veterinarian (2004-2007)
Iowa Veterinary Medical Association Foundation, President (2003-2005)
Past President (2003-4), President (2002-3), President Elect (2001-2), Vice Pres. (2000-1) Iowa Veterinary Medical Association
Pathology Section Leader, Iowa State University Veterinary Diagnostic Laboratory (1999-2001)

Memberships  

American Association of Veterinary Laboratory Diagnosticians
American Association of Swine Veterinarians
American Association of Bovine Practitioners
Academy of Veterinary Consultants
American Veterinary Medical Association
Iowa Veterinary Medical Association
Iowa Farm Bureau Association
Iowa Corn Growers Association
Associate Member Iowa Cattlemen’s Association
Associate Member Iowa Pork Producers Association
Associate member Iowa State Dairy Association
Associate Member Iowa Sheep and Wool Producers Association

Selected Publications  

Google Scholar Page

Most recent 20 from over 200 peer reviewed scientific manuscripts:

Tian D, Ni YY, Zhou L, Opriessnig T, Cao D, Pineyro P, Yugo DM, Overend C, Cao Q, Lynn Heffron C, Halbur PG, Pearce DS, Calvert JG, Meng X-J. Chimeric porcine reproductive and respiratory syndrome virus containing shuffled multiple envelope genes confers cross-protection in pigs. Virology 485:402-413, 2015.

Xiao CT, Halbur PG, Opriessnig T. Global molecular genetic analysis of porcine circovirus type 2 (PCV2) sequences confirms the presence of four main PCV2 genotypes and reveals a rapid increase in PCV2d. Journal of General Virology, doi:10.1099/vir.0.000100, 2015.

Opriessnig T, Xiao CT, Gerber PF, Zhang J, Halbur P. Porcine epidemic diarrhea virus RNA present in commercial spray-dried porcine plasma is not infectious to naïve pigs. PLoS One. 2014 Aug 12;9(8):e104766. doi: 10.1371/journal.pone.0104766. eCollection 2014.

Gerber PF. Xiao CT, Chen Q, Zhang J, Halbur PG, Opriessnig T. The spray-drying process is sufficient to inactivate infectious porcine epidemic diarrhea virus in plasma.  Veterinary Microbiology 174(1):86-92, 2014.

Opriessnig T, Xiao CT, Gerber PF, Halbur PG. Identification of recently described porcine parvoviruses in archived North American samples from 1996 and association with porcine circovirus associated disease. Veterinary Microbiology 173(1):9-16, 2014.

Opriessnig T, Xiao CT, Gerber PF, Halbur PG, Matzinger SR, Meng XJ. Mutant USA strain of porcine circovirus type 2 (mPCV2) exhibits similar virulence to the classical PCV2a and PCV2b stains in caesarian-derived colostrums-deprived pigs. Journal of General Virology 95 (Pt11):2495-2503, 2014.

Opriessnig T, Gerber PF, Xiao CT, Halbur PG, Matzinger SR, Meng XJ. Commercial PCV2a-based vaccines are effective in protecting naturally PCV2b-infected finisher pigs against challenge with a 2012 mutant PCV2.  Vaccine 32(34):4342-4348, 2014.

Giménez-Lirola LG, Gerber PF, Rowland RR, Halbur PG, Huang YW, Meng XJ, Opriessnig T. Development and validation of a 4-plex antibody assay for simultaneous detection of IgG antibodies against Torque teno sus virus 1 (TTSuV1), TTSuV2, and porcine reproductive and respiratory syndrome virus types 1 and 2. Research in Veterinary Science 96(3):543-550, 2014.

Gerber PF, Giménez-Lirola LG, Halbur PG, Zhou L, Meng XJ, Opriessnig T. Comparison of commercial enzyme-linked immunosorbent assays and fluorescent microbead immunoassays for detection of antibodies against porcine reproductive and respiratory syndrome virus in boars. Journal of Virological Methods 197:63-66, 2014.

Jiang YH, Xiao CT, Yin SH, Gerber PF, Halbur PG, Opriessnig T. High prevalence and genetic diversity of porcine bocaviruses in pigs in the USA, and identification of multiple novel porcine bocaviruses. Journal of General Virology 95(2):453-465, 2014.

Hemann M, Beach NM, Meng XJ, Wang G, Halbur PG, Opriessnig T. A live-attenuated and an inactivated chimeric porcine circovirus (PCV) 1-2 vaccine are both effective at inducing a humoral immune response and reducing PCV2 viremia and intrauterine infection in female swine of breeding age. Canadian Journal of Veterinary Research 78(1):8-16, 2014.

Giménez-Lirola LG, Jiang YH, Sun D, Hoang H, Yoon KJ, Halbur PG, Opriessnig T. Simultaneous detection of antibodies against Apx toxins ApxI, ApxII, ApxIII, and ApxIV in pigs with known and unknown Actinobacillus pleuropneumoniae exposure using a multiplexing liquid array platform. Clinical and Vaccine Immunology 21(1):85-95, 2014.

Opriessnig T, Gerber PF, Xiao CT, Mogler M, Halbur PG. A commercial vaccine based on PCV2a and an experimental vaccine based on a variant mPCV2b are both effective in protecting pigs against challenge with a 2013 U.S. variant mPCV2b strain. Vaccine 32(2):230-237, 2014.

Wang R, Xiao Y, Opriessnig T, Ding Y, Yu Y, Nan Y, Ma Z, Halbur PG, Zhang YJ. Enhancing neutralizing antibody production by an interferon-inducing porcine reproductive and respiratory syndrome virus strain. Vaccine 31:5537-5543, 2013.

Owolodun OA, Giménez-Lirola LG, Gerber PF, Sanford BJ, Feagins AR, Meng XJ, Halbur PG, Opriessnig T. Development of a fluorescent microbead-based immunoassay for the detection of hepatitis E virus IgG antibodies in pigs and comparison to an enzyme-linked immunoassay. Journal of Virological Methods 193(2):278-283, 2013.

Yin SH, Xiao CT, Gerber PF, Beach NM, Meng XJ, Halbur PG, Opriessnig T. Concurrent porcine circovirus type 2a (PCV2a) or PCV2b infection increases the rate of amino acid mutations of porcine reproductive and respiratory syndrome virus (PRRSV) during serial passages in pigs. Virus Research 178:445-451, 2013.

Gerber P, Johnson J, Shen H, Striegel D, Xiao C-T, Halbur P, Opriessnig T. Association of concurrent porcine circovirus (PCV) 2a and 2b infection with PCV associated disease in vaccinated pigs. Research in Veterinary Science. 95(2):775-781, 2013.

Xiao CT, Giménez-Lirola LG, Jiang YH, Halbur PG, Opriessnig T. Characterization of a novel porcine parvovirus tentatively designated PPV5.  PLoS One. June 7:8(6):e65312.doi:10.371/journal.pone.0065312, 2013.

Xiao CT, Halbur PG, Opriessnig T.  Molecular evolutionary genetic analysis of emerging parvoviruses identified in pigs.  Infection, Genetics and Evolution 16:369-376, 2013.

Xiao CT, Halbur PG, Opriessnig T.  Complete genome sequence of a novel porcine parvovirus (PPV) provisionally designated PPV5.  Genome Announcements Jan:1(1). doi:pii: e00021-12. 10.1128/genomeA, 2013.