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It is very important to understand the mode of action of drugs (pharmacology). My teaching focuses on those drugs that acts on ion-channels and includes the action of cardiac drugs, drugs that act on nematode parasites, with classes for neuroscience and toxicology graduate students and DVM students.
We are interested in molecular and cellular pharmacology with a focus on drugs that act on ion-channels of nematodes, including those parasites that cause disease in humans in the developing world and in animals.
Our work is supported by NIH and NSF and involves molecular, cellular, pharmacological, electrophysiological, Xenopus expression and microfluidic techniques to study the effects of drugs like emodepside, pyrantel, derquantel and ivermectin on a range of membrane ion-channels. We study a range of nematodes including, C. elegans, Brugia malayi, Ascaris suum, Oesophagostomum dentatum and Haemonchus contortus. We encourage potential graduate students and post-doctoral researchers to contact us if they are interested in our research.