Qijing Zhang

BVsc, MS, PhD
Professor and Associate Dean of Research and Graduate Studies
Dr. Frank K. Ramsey Endowed Chair
2520 Vet Med
Education & Certifications  

B.V.Sc    Shandong Agricultural University (China)     1983          Vet Medicine
M.S.       National Inst. Veterinary Biologics (China)   1986          Vet Microbiology
Ph.D.     Iowa State University                                 1994          Immunobiology
Postdoc University of Missouri-Columbia                   1994-1997  Molecular Microbiology

Research Focus & Interests  

Food safety; antibiotic resistance; bacterial pathogenesis; pathogen-host interactions; prevention and control of infectious diseases.

Honors & Awards  

Endowed Frank K. Ramsey Chair in Veterinary Medicine, Iowa State University, 2003-2012 and 2017-present.
Pfizer Award for Research Excellence, Iowa State University, 2007.
Fellow, American Academy of Microbiology, elected 2015.
Honorary Diplomate, American College of Veterinary Microbiologists, elected 2017.


VMPM Departmental Officer of Graduate Education
Chair, CVM International Development Committee
Chair, Research Advisory Committee
Associate Dean for Research and Graduate Studies
Chair, Division Z (Animal Health), American Society for Microbiology
Chair, USDA NC1202 Committee-Enteric Diseases of Food Animals: Enhanced Prevention, Control and Food Safety.
Council Member, CRWAD


American Society for Microbiology
Conference of Research Workers in Animal Diseases
American Association for the Advancement of Science
American Veterinary Medical Association
American Association of Avian Pathologists

Selected Publications  

Full publication list on PubMedGoogle Scholar

Li, H., Y. Wang, Q. Fu, Y. Wang, X. Li, C. Wu, Z. Shen, Q. Zhang, P. Qin, J. Shen & X. Xia. 2017. Integrated genomic and proteomic analyses of high-level chloramphenicol resistance in Campylobacter jejuni. Scientific Reports 7: 16973. doi:10.1038/s41598-017- 17321-1

Dai, L., O Sahin, Y Tang, Q Zhang. 2017. A mutator phenotype promoting the emergence of spontaneous oxidative stress resistant mutants in Campylobacter jejuni. Appl. Environ. Microbiol. 83: e01685-17.

 Tang, Y., R. J. Meinersmann, O. Sahin, Z. Wu, L. Dai, J. Carlson, J. Plumblee, L. Genzlinger, J. T. LeJeunee, and Q. Zhang. 2017. Wide but variable distribution of a hypervirulent Campylobacter jejuni clone in beef and dairy cattle in the United States. Appl. Environ. Microbiol. 83: e01425-17 (featured in Spotlight).

Su, C.-C., L. Yin, N. Kumar, L. Dai, A. Radhakrishnan, J. R. Bolla, H.-T. Lei, T.-H. Chou, K. Rajashankar, Q. Zhang, Y.-K. Shin, and E. Yu. 2017 Structures and transport dynamics of the Campylobacter jejuni multidrug efflux pump CmeB. Nature Communications. 8:  171. DOI: 10.1038/s41467-017-00217z.

Tang, Y., L. Dai, O. Sahin, Z. Wu, M. Liu, and Q. Zhang. 2017. Emergence of a plasmid-borne multidrug resistance gene cfr(C) in foodborne pathogen Campylobacter. J. Antimicrob. Chemother. DOI:10.1093/jac/dkx023

Wang, Y., R. Zhang, J. Li, Z. Wu, W. Yin, S. Schwarz, J. Tyrrell, Y. Zheng, S. Wang, Z. Shen, Z. Liu, J. Liu, L. Lei, M. Li, Q. Zhang, C. Wu, Q. Zhang, Y. Wu, T.R. Walsh, J. Shen. 2017. Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1 in Chinese poultry production. Nature Microbiology 2, Article number: 16260. doi:10.1038/nmicrobiol.2016.260

Sahin, O., S. Terhorst, E. Burrough, Z. Shen, Z. Wu, L. Dai, Y. Tang, P. Plummer, J. Ji, M. Yaeger, and Q. Zhang. 2017. Key role of capsular polysaccharide in the induction of systemic infection and abortion by hypervirulent Campylobacter jejuni. Infect. Immun. vol. 85 no. 6 e00001-17.

Sun, J., R.S. Yang, Q. Zhang, Y. Feng, L.X. Fang, J. Xia, L. Lia, X.Y. Lv, J.H. Duan, X.P. Liao, and Y.H. Liu. 2016. Co-transfer of blaNDM-5 and mcr-1 by an IncX3-X4 hybrid plasmid in Escherichia coli. Nature Microbiology 1, Article number: 16176. doi: 10.1038/nmicrobiol.2016.176.

Wu Z, Periaswamy B, Sahin O, M. Yaeger, P. Plummer, W. Zhai, Z. Shen, L. Dai, S. Chen, and Q. Zhang. 2016. Point mutations in the major outer membrane protein drive hypervirulence of a rapidly expanding clone of Campylobacter jejuni. Proc. Natl. Acad. Sci. U. S. A. 113: 10690-10695.

Yao, H., Z. Shen , Y. Wang, F. Deng, D. Liu,  G. Naren, L. Dai, C. Su, B. Wang, S. Wang, C. Wu, E.W. Yu, Q. Zhang, and J. Shen. 2016. Emergence of a potent multidrug efflux pump variant that enhances Campylobacter resistance to multiple antibiotics. mBio 7:e01543-16. doi:10.1128/mBio.01543-16.

Shen Z., R.D. Patil, O. Sahin, Z. Wu, X.Y. Pu, L. Dai, P. J. Plummer, M. Yaeger, and Q Zhang. 2016. Identification and functional analysis of two toxin-antitoxin systems in Campylobacter jejuni. Mol Microbiol. 101: 909–923.

Deng, F., J. Shen, M. Zhang, C. Wu, Q. Zhang, and Y. Wang. 2015. Constitutive and inducible expression of the ribosomal RNA methylase gene erm(B) in Campylobacter. Antimicrob. Agents Chemother. 59(10):6661-4.

Qin, S., Q. Hui, Q. Zhang, D. Zhao, Z.Z. Liu, H. Tian, L. Xu, H. Xu, M. Zhou, X. Feng, Hong-Min Liu. 2015. Emergence of extensively drug-resistant Proteus mirabilis harboring a conjugative NDM-1 plasmid and a novel Salmonella genomic island 1 variant (SGI1-Z). Antimicrob. Agents Chemother. 59(10): 6601–6604.

Dai, L., W. T Muraoka, Z. Wu, O. Sahin, and Q. Zhang. 2015. A single nucleotide change in mutY increases the emergence of antibiotic-resistant Campylobacter jejuni mutants. J. Antimicrob. Chemother. 70:2739-48; DOI:10.1093/jac/dkv190

Wu, Z., O. Sahin, F. Wang, and Q. Zhang. 2014. Proteomic identification of immunodominant membrane-related antigens in Campylobacter jejuni associated with sheep abortion. J. Proteomics. 99: 111-122.

Qin, S.S., Y. Fu, Q. Zhang, H. Qi, J.G. Wen, H. Xu, L. Xu, L. Zeng, H. Tian, L. Rong, Y. Li, L. Shan, H. Xu, Y. Yu, X. Feng, and H.M. Liu. 2014. High incidence and endemic spread of NDM-1 positive Enterobacteriaceae in Henan province, China. Antimicrob. Agents Chemother. 58(8):4275-4282.

Sahin, O., C. Fitzgerald, S. Stroika, S. Zhao, R. Sippy, P. Kwan, P. Plummer, J. Han, M. Yaeger, and Q. Zhang.  2012. Molecular Evidence for zoonotic transmission of an emergent highly pathogenic Campylobacter jejuni clone in the United States. J. Clin. Microbiol. 50(3):680-7.

Luangtongkum, T., Z. Shen, V. Seng, O. Sahin, B. Jeon, P. Liu, and Q. Zhang. 2012. Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. Antimicrob. Agents Chemother. 56(3):1300-8.