Qijing Zhang

BVsc, MS, PhD
Clarence Hartley Covault Distinguished Professor
Frank K. Ramsey Endowed Chair in Veterinary Medicine
Associate Dean for Research and Graduate Studies
515-294-9348
2520 Vet Med
Education & Certifications  

B.V.Sc            Shandong Agricultural University (China)                 1983                Vet Medicine
M.S.                National Inst. Veterinary Biologics (China)              1986                Vet Microbiology
Ph.D.               Iowa State University                                            1994                Immunobiology
Postdoc           University of Missouri-Columbia                              1994-1997       Molecular Microbiology

Research Focus & Interests  

Food safety; antibiotic resistance; bacterial pathogenesis; pathogen-host interactions; prevention and control of infectious diseases.

Honors & Awards  

Endowed Frank K. Ramsey Chair in Veterinary Medicine, Iowa State University, 2003-2012 and 2017-present
Pfizer Award for Research Excellence, Iowa State University, 2007
Fellow, American Academy of Microbiology, elected 2015
Honorary Diplomate, American College of Veterinary Microbiologists, elected 2017
Fellow, AAAS, elected 2018

Leadership/Committees/Council  

VMPM Departmental Officer of Graduate Education
Chair, CVM International Development Committee
Chair, Research Advisory Committee
Associate Dean for Research and Graduate Studies
Chair, Division Z (Animal Health), American Society for Microbiology
Chair, USDA NC1202 Committee-Enteric Diseases of Food Animals: Enhanced Prevention, Control and Food Safety.
Council Member and President, CRWAD

Memberships  

American Society for Microbiology
Conference of Research Workers in Animal Diseases
American Association for the Advancement of Science
American Veterinary Medical Association
American Association of Avian Pathologists

Selected Publications  

Full publication list on PubMedGoogle Scholar

Dai, L., O. Sahin, Y. Tang, and Q. Zhang. 2017. A mutator phenotype promoting the emergence of spontaneous oxidative stress resistant mutants in Campylobacter jejuni. Appl. Environ. Microbiol. 83: e01685-17.

Tang, Y., R. J. Meinersmann, O. Sahin, Z. Wu, L. Dai, J. Carlson, J. Plumblee, L. Genzlinger, J. T. LeJeunee, and Q. Zhang. 2017. Wide but variable distribution of a hypervirulent Campylobacter jejuni clone in beef and dairy cattle in the United States. Appl. Environ. Microbiol. 83: e01425-17 (featured in Spotlight).

Su, C.-C., L. Yin, N. Kumar, L. Dai, A. Radhakrishnan, J. R. Bolla, H.-T. Lei, T.-H. Chou, K. Rajashankar, Q. Zhang, Y.-K. Shin, and E. Yu. 2017 Structures and transport dynamics of the Campylobacter jejuni multidrug efflux pump CmeB. Nature Communications. 8:  171. DOI: 10.1038/s41467-017-00217z.

Tang, Y., L. Dai, O. Sahin, Z. Wu, M. Liu, and Q. Zhang. 2017. Emergence of a plasmid-borne multidrug resistance gene cfr(C) in foodborne pathogen Campylobacter. J. Antimicrob. Chemother. DOI:10.1093/jac/dkx023

Sahin, O., S. Terhorst, E. Burrough, Z. Shen, Z. Wu, L. Dai, Y. Tang, P. Plummer, J. Ji, M. Yaeger, and Q. Zhang. 2017. Key role of capsular polysaccharide in the induction of systemic infection and abortion by hypervirulent Campylobacter jejuni. Infect. Immun. vol. 85 no. 6 e00001-17.

Wu Z, Periaswamy B, Sahin O, M. Yaeger, P. Plummer, W. Zhai, Z. Shen, L. Dai, S. Chen, and Q. Zhang. 2016. Point mutations in the major outer membrane protein drive hypervirulence of a rapidly expanding clone of Campylobacter jejuni. Proc. Natl. Acad. Sci. U. S. A. 113: 10690-10695.

Yao, H., Z. Shen , Y. Wang, F. Deng, D. Liu,  G. Naren, L. Dai, C. Su, B. Wang, S. Wang, C. Wu, E.W. Yu, Q. Zhang, and J. Shen. 2016. Emergence of a potent multidrug efflux pump variant that enhances Campylobacter resistance to multiple antibiotics. mBio 7:e01543-16. doi:10.1128/mBio.01543-16.

Shen Z., R.D. Patil, O. Sahin, Z. Wu, X.Y. Pu, L. Dai, P. J. Plummer, M. Yaeger, and Q Zhang. 2016. Identification and functional analysis of two toxin-antitoxin systems in Campylobacter jejuni. Mol Microbiol. 101: 909–923.

Dai, L., W. T Muraoka, Z. Wu, O. Sahin, and Q. Zhang. 2015. A single nucleotide change in mutY increases the emergence of antibiotic-resistant Campylobacter jejuni mutants. J. Antimicrob. Chemother. 70:2739-48; DOI:10.1093/jac/dkv190

Sahin, O., C. Fitzgerald, S. Stroika, S. Zhao, R. Sippy, P. Kwan, P. Plummer, J. Han, M. Yaeger, and Q. Zhang.  2012. Molecular Evidence for zoonotic transmission of an emergent highly pathogenic Campylobacter jejuni clone in the United States. J. Clin. Microbiol. 50(3):680-7.

Luangtongkum, T., Z. Shen, V. Seng, O. Sahin, B. Jeon, P. Liu, and Q. Zhang. 2012. Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. Antimicrob. Agents Chemother. 56(3):1300-8.